Université de Rouen Normandie

Dissociating task, semantic, and response conflict in cognitive aging: evidence from a low-cognitive control Stroop paradigm

Abstract Cognitive aging is often associated with increased Stroop interference, but it remains unclear whether this reflects a broad decline in inhibitory control or selective impairments in specific conflict-resolution mechanisms. The present study examined age-related differen...

Intermittent or Continuous Renal-Replacement Therapy in Acute Kidney Injury

BackgroundThe preferred method of renal-replacement therapy for acute kidney injury in critically ill patients remains uncertain. MethodsIn this multicenter, open-label, noninferiority trial, we randomly assigned critically ill adults with acute kidney injury who had indications...

Profiles of Post-traumatic Symptoms and Well-Being Among Young Adults: Associations With Early Adversity, Psychopathology and Social Support

Post-traumatic stress symptoms (PTSS) are common in young adulthood, yet symptom-based approaches provide only a partial account of mental health. The dualcontinua model conceptualizes mental health as the coexistence of psychological distress and psychological well-being (PWB),...

Low-energy electron collisions with BH+

BH+ ions are expected to play an important role in boron-containing plasmas relevant to fusion environments such as ITER, where low-energy electrons drive a variety of inelastic and reactive scattering processes. In particular, dissociative recombination, vibrational excitation,...

Natural History of Rare Tumor Risk Syndromes: A Scoping Review to Inform Cost-Effectiveness Models

Background Hereditary cancer syndromes account for approximately 10% of all cancers. Many of these, classified as rare tumor risk syndromes (RTRS), lack comprehensive data on natural history, lifetime cancer risk, and the long-term impact of surveillance. These evidence gaps limi...

Association between the site of emergency care and patient-centered outcomes in patients with cancer: rationale and design of the French COVER cohort

Patients living with cancer now account for a substantial and growing share of emergency department (ED) visits and carry a high burden of hospitalization and in-hospital death. Their acute presentations are frequently multifactorial - driven by disease progression, treatment tox...

Monitoring symptoms and performance in rehabilitation: Can we detect COPD exacerbation?

Background In patients with COPD, exacerbations mark disease progression, with significant reduction in quality of life and impact on mortality. Early detection is crucial to mitigate their consequences. The aim of this study was to investigate whether monitoring symptoms and exe...

Correlative microscopy reveals chemical short-range order and native oxide in medium-entropy alloys

High- and medium-entropy alloys can exhibit exceptional sets of mechanical and catalytic properties underpinned by the vast array of local atomic arrangements. Among the key features governing properties is the self-assembly of specific atomic neighborhoods, a process known as ch...

Immune‐related adverse events with mogamulizumab in cutaneous T‐cell lymphoma: A multicentre study

BACKGROUND: Mogamulizumab, an anti-CCR4 monoclonal antibody used in advanced mycosis fungoides (MF) and Sezary syndrome (SS), also depletes regulatory T cells, potentially leading to immune-related adverse events (irAEs). Unlike mogamulizumab-associated rash (MAR), other irAEs re...

SENIOR ‐ IPI : An easily applicable prognostic index for first‐line large B‐cell lymphomas patients >80 years treated with curative intent

Summary Using LYmphoma Study Association clinical trials combining 438 first‐line large B‐cell lymphomas (LBCL) patients >80 years old, we defined SENIOR‐IPI, an easily applicable prognostic index for this elderly population treated with an anti‐CD20‐miniCHOP (cyclophosphamide, d...

Linear Fluctuation of Interfaces in Glauber–Kawasaki Dynamics

Abstract In this article, we find a scaling limit of the space-time mass fluctuation field of Glauber + Kawasaki particle dynamics around its hydrodynamic mean curvature interface limit. Here, the Glauber rates are scaled by $$K=K_N$$ K = K N (with $$K_N\uparrow \infty $$ K N ↑ ∞...

Serum GFAP and Age Accurately Distinguish AQP4 ‐ IgG Positive and Double Seronegative NMOSD From MOGAD After a Recent Attack

BACKGROUND: Serum neurofilament-light chain (sNfL) and glial fibrillary acidic protein (sGFAP) are associated with multiple sclerosis (MS) activity. This study aimed to identify patient- and disease-level determinants of sNfL and sGFAP and to evaluate their ability to support dif...

Hydroalkylation and hydroacylation of trifluoromethyl olefins by N-centered direct hydrogen atom transfer photocatalysis

The selective functionalization of trifluoromethyl olefins, while keeping the essential trifluoroalkyl moiety intact, remains a synthetic challenge. In this study, we report the use of an acridinium amidate as a direct hydrogen atom transfer (d-HAT) photocatalyst for the mild and...

Low graft re‐rupture rate after primary ACL reconstruction using a modified MacIntosh iliotibial band technique with gracilis augmentation: Minimum 6‐year follow‐up

PURPOSE: Combined intra- and extra-articular anterior cruciate ligament (ACL) reconstruction has gained renewed interest to improve rotational stability and reduce graft failure. This study evaluated graft re-rupture rates, functional and return-to-sport (RTS) outcomes at a minim...

Design of Potent, Non-Toxic Antimicrobial Agents Derived from the Frog Skin Peptide Raniseptin-PL Active Against Gram-Negative ESKAPE+ Pathogens

Background/Objectives: The frog skin peptide raniseptin-PL (GVFDTVKKIGKAVGKFALGVAKNYLNS.NH2) is active against a range of antibiotic-resistant bacteria including ESKAPE+ pathogens, but its therapeutic potential is limited by high cytotoxicity against mammalian cells. The study ai...

A Unified Algebraic Framework for Hedge Automata Using Horizontal Language Expressions

This paper presents a unified algebraic and computational framework for classical hedge automata and related algebraic structures. The framework extends the open-source TARgET library with support for hedge-based structures. The formal development discusses classical hedge automa...

Effect Modification of Rescue Stenting in ICAS-Related Middle Cerebral Artery Occlusion: The Role of Thrombectomy Failure, Stenosis Severity, and ASPECTS

Rescue stenting (RS) is increasingly used for intracranial artery stenosis-related large vessel occlusion (ICAS-LVO), but optimal patient selection remains uncertain. We investigated the baseline and procedural factors associated with receiving RS and whether they modified the as...

The Chornobyl Dogs: Why Scientific Evaluation Must Accompany Population Management

Nearly four decades after the 1986 reactor explosion, several hundred semi-feral dogs persist within the Chornobyl Exclusion Zone. Genomic work has characterised their population structure and shown that radiation-induced mutation does not, on current evidence, drive the differen...

Dietary prevention of undernutrition reduces intestinal inflammation associated with an anti-inflammatory profile of gut microbiota in a preclinical model

Patients with inflammatory bowel diseases (IBD) have a high-risk for undernutrition. Undernutrition is associated with higher complications such as an increased mortality rate, a higher disease activity and an impaired quality of life in IBD patients. The aim of this study was to...

General heat release rate surrogates for NH3/H2/N2 and H2 flames using Raman/Rayleigh/LIF accessible species

Accurate estimation of the heat-release rate (HRR) is essential for understanding and controlling ammonia–hydrogen combustion, yet conventional experimental surrogates are strongly dependent on operating conditions and typically rely on radicals measured by laser-induced fluoresc...