Universitätsklinikum Aachen

Pediatric intensive care follow-up in Germany is rarely established and highly heterogeneous: a nationwide survey of 20 PICUs

BACKGROUND: Survival after pediatric critical illness has improved substantially, but many survivors and their families experience long-term physical, neurocognitive, psychological and social sequelae, summarized as post-intensive care syndrome in pediatrics and in families. Stru...

Optimization of Material and Printing Parameter Selection for FDM 3D-Printed Bone Models for Osteotomy Training: A Biomechanical and User-Based Evaluation

Although additive manufacturing enables cost-effective surgical training models, variation in materials and printing parameters limits standardization. This study combined biomechanical testing and user evaluation to identify fused deposition modeling (FDM) settings for osteotomy...

Bilateral internal carotid artery dissection and occlusion in Eagle syndrome treated with emergency single-session bilateral carotid artery stenting: a case report

Eagle syndrome (stylocarotid variant) is a rare but potentially life-threatening cause of internal carotid artery (ICA) dissection and ischemic stroke. Bilateral ICA dissection due to Eagle syndrome has been treated with both staged and single-session bilateral carotid stenting e...

DECIDER-2: Prospective randomized multicenter phase III trial of decitabine and venetoclax administered in combination with all-trans retinoic acid or placebo in patients with acute myeloid leukemia who are ineligible for induction chemotherapy

Abstract Background Acute myeloid leukemia (AML) is predominantly a disease of older patients with a poor long-term survival. Approval of the combination of venetoclax (VEN) with azacitidine (AZA) or decitabine (DAC) in the European Union in 2021 for the treatment of patients wit...

Feasibility of a German High-Frequency Neonatal and Pediatric Intensive Care Dataset (AIx-Neo-Guard Dataset): Secondary Data Cohort Study

BACKGROUND: Available information about existing neonatal and pediatric intensive care datasets is scarce. OBJECTIVE: The objective was to evaluate the feasibility of a monocentric high-frequency dataset of neonatal and pediatric intensive care patients in a cohort study. METHODS...