Universitat Internacional de Catalunya

Expired endoscopic devices remain sterile and functional: an international multicentre study challenging current shelf-life criteria

Background and study aims Expired medical devices represent an environmental and economic concern, yet their magnitude and true shelf life remain poorly defined. We aimed to quantify the volume and cost of expired endoscopic devices and evaluate their sterility and functionality...

La Capacidad De No Poder Hacer Milagros: Reflexiones Sobre El Abastecimiento De Las Expediciones De 1715, 1718 y 1720. 1

Today there is a great discussion about the effects that the organization of military expeditions had on the civilian population and the economy of the province of departure. The issue is relevant because in order to carry them out, the State must have a great capacity to mobiliz...

Maxillomandibular Advancement Guided by the Barcelona Line, a Facial Soft-Tissue Reference, in Patients with Obstructive Sleep Apnea: A Feasibility Study

Maxillomandibular advancement (MMA) represents an effective surgical treatment for individuals with obstructive sleep apnea (OSA) when conservative therapies fail. However, variability in surgical planning methods limits predictability and standardization of outcomes. This retros...

Digital solutions for tackling mental health in cancer patients and their families: The ALTHEA project

Despite advances in cancer treatment, the growing global cancer burden underscores the need for comprehensive and supportive care to address the needs of patients and their families. However, access to psycho-oncological support remains often limited across healthcare systems. Th...

A nutrient-sensitive CPT1C-ABHD6 axis regulates BMP homeostasis and endolysosomal function in hypothalamic neurons

The endolysosomal system is central to neuronal homeostasis, yet how nutrient sensing regulates endolysosomal lipids remains poorly understood. Bis(monoacylglycero)phosphate (BMP), a signature phospholipid of late endosomes, is required for intraluminal vesicle formation, cholest...

Long-Term Aesthetic Performance of Freehand Direct Anterior Composite Resin Restorations: A Systematic Review and Meta-Analysis of Colour Alteration, Marginal Discolouration, and Surface-Quality Deterioration

Background: Freehand direct composite resin veneers offer a minimally invasive approach for managing aesthetic alterations in anterior teeth; however, their long-term colour alteration and surface performance remain uncertain. This systematic review evaluated colour alteration, m...

Progressive Structural Failure in Complex Prosthetic Joint Infection Followed by Amputation

Background: Prosthetic joint infections (PJI) are complex complications of arthroplasty. Detailed sequential polymicrobial infection during long clinical courses, with multiple interventions and sustained antibiotic pressure, has been described sparingly. Methods: We present a ca...

Plasma Aβ42/Aβ40 predicts longitudinal amyloid pathology and clinical progression in amyloid-PET negative individuals with subjective cognitive decline

Early detection of amyloid-β (Aβ) pathology is critical for timely intervention in Alzheimer’s disease (AD). Changes in plasma Aβ42/Aβ40 levels appear early in the AD continuum, but whether they precede amyloid deposition detected by Aβ-PET requires further research. Data from 16...

From feasibility to neuroanatomic validity of remote cognitive smartphone assessments in early Alzheimer’s disease

ABSTRACT Digital health technologies (DHT) offer a promising solution to the timely identification of early Alzheimer’s disease (eAD) to enable early treatment. This study evaluated the feasibility, acceptability, adherence, reliability, and preliminary clinical and content valid...

Assessing Students’ Self-Perceived Eco-Social Competences in Higher Education: A Rubric-Based Approach to Sustainability and Global Competence

This study analyses changes in university students’ self-perceived eco-social competences through active methodologies linked to holistic sustainability and human rights. A multidimensional rubric based on the KNOW–CARE–DO model was applied to assess four eco-social competences:...

Presence of Dolosigranulum pigrum in the nasopharynx and its relationship with respiratory health status in paediatric population

ABSTRACT Background Respiratory tract infections range from asymptomatic colonisation to an invasive disease. Recent studies suggest that nasopharyngeal microbiota may influence this variability. Emerging evidence points to Dolosigranulum pigrum, a nasopharyngeal commensal, as a...

Radiomics and artificial intelligence in pituitary adenomas (PitNETs): from imaging biomarkers to clinical translation

Abstract Pituitary neuroendocrine tumors (PitNETs) are common intracranial neoplasms with heterogeneous hormonal activity, invasiveness, and treatment response. Conventional MRI is central to diagnosis, but is limited in quantifying tumor heterogeneity and predicting clinically r...

A low-cost imaging platform for quantitative characterisation of scaffold surface macrotopography with potential application in craniofacial tissue engineering

Craniofacial bone regeneration is a demanding application of tissue engineering (TE) in which scaffold architecture—pore size, shape and spatial distribution—is a determinant of regenerative success, so that reliable geometric quality control is a prerequisite for translation. Co...

Antibacterial Interventions for Orthodontic Appliances; Surface Modifications, Coatings and Bulk-Incorporated Antibacterial Agents: Materials, Mechanisms and Clinical Application—A Scoping Review

Biofilm accumulation on orthodontic appliances is a recognized risk factor for white spot lesion formation and caries during treatment. Antibacterial surface modifications and coating strategies have been proposed as appliance-level preventive approaches. Studied interventions in...

Emergency Department-Based Screening and Linkage-to-Care for Hepatitis B, C, and D in a Referral Hospital in Barcelona, Spain: Reduction in Hepatitis C Prevalence After Five Years

Background: Emergency Department (ED) viral hepatitis screening programs typically report short-term outcomes. We evaluated the medium-term impact of an ED-based screening for Hepatitis C (HCV), Hepatitis B (HBV), and Hepatitis D (HDV) viruses. Methods: Prospective opportunistic...

Burden, perception of stigma, and gender differences among informal care partners of individuals with mild cognitive impairment

Background Caring for individuals with mild cognitive impairment (MCI) is increasingly recognized as a significant clinical challenge. However, the latent burden, driven by perceived stigma and gender-specific vulnerabilities, remains poorly characterized during these early stage...

Efficacy of a probiotic formula in the management of menopausal symptoms and quality of life: a randomized controlled trial

OBJECTIVES: Estrogen decline during menopause transition is associated with physical and psychological symptoms that impair overall well-being. In a previous randomized trial, a probiotic formula comprising Levilactobacillus brevis KABP052, Lactiplantibacillus plantarum KABP051,...