Universidade Estadual Paulista (Unesp)

Smart Coatings Integrating Antimicrobial and Tissue‐Remodeling Functions for Implant Interfaces

AIM: This study aimed to assess the antimicrobial performance and biocompatibility of our drug delivery platform, based on layer-by-layer (LbL) coating incorporating tetracycline (TC) complexed with anionic β-cyclodextrin (TCβCD) and a pH-responsive poly(methacrylic acid) (PMAA)...

Population density and habitat use of the yellow land crab Johngarthia lagostoma on the remote Trindade Island, Brazil: implications for island conservation

Abstract Several land crab species inhabit oceanic islands worldwide, where they often dominate terrestrial arthropod communities, and act as ecosystem engineers. In the South Atlantic, Johngarthia lagostoma is the only gecarcinid species, endemic to Rocas Atoll, Fernando de Noro...

Pharmacological Modulation of Nrf2 Signaling Regulates Oxidative Stress, Inflammation, and Alveolar Bone Loss in Experimental Periodontitis

AIM: To investigate whether pharmacological modulation of Nrf2 signaling influences oxidative stress, inflammatory responses, and periodontal tissue destruction in experimental ligature-induced periodontitis. METHODS: Ligature-induced experimental periodontitis was established in...

Geophysical modeling in a drainage basin with a gold geochemical anomaly, Cerro da Cria Region, Vila Nova do Sul, Rio Grande do Sul (Brazil)

Gold plays a central role in the global economy as a store of value, a strategic asset, and an important raw material for industrial and technological applications. In mineral exploration, geochemical prospecting allows the delineation of anomalous drainage basins and the identif...

Chronic low back pain and sleep disturbances among agro-industrial and industrial workers: a scoping review

Abstract Aim To map and synthesize the available scientific evidence on the relationship between chronic low back pain and sleep-related outcomes among agro-industrial and industrial workers exposed to high physical demands. Subject and methods A scoping review was conducted foll...

Assessing Water and Sediment Contamination in the Sub-Middle São Francisco River (Brazil): Combining Physicochemical Analyses, Trace Metals, and Allium cepa L. Ecotoxicity

The Sub-middle São Francisco River (Northeast Brazil), a key water resource for regional socioeconomic development, is increasingly threatened by urban, industrial, and intensive irrigated agricultural activities. This study aimed to assess physicochemical parameters, nutrient an...

Islands and traversable wormholes

A bstract We study information recovery in black hole evaporation using traversable wormhole protocols in AdS 2 Jackiw-Teitelboim gravity with matter fields coupled to an external bath. By introducing a simple non-local interaction between left and right radiation regions, we gen...

The secret of the saws: historical DNA analysis reveals global genetic diversity loss in a highly threatened species

Abstract Genetic diversity is critical to long-term survival of species but can be eroded by population declines driven by human pressures. Temporal genetic monitoring of threatened species can reveal changes in genetic diversity over time, providing key data for conservation. Sp...

Genome-wide analysis of lipoxygenase genes in Coffea arabica and its diploid progenitors

Lipoxygenase proteins (LOXs) play a crucial role in plant growth, development, and defense notably through their involvement in jasmonic acid (JA) biosynthesis. Here, we aimed to identify and characterize genes encoding lipoxygenases in three coffee species, Coffea arabica, Coffe...

Nanosilica increases tolerance to Cu toxicity in soybean seeds by reducing Cu uptake and improving nitrogen use efficiency

The treatment of soybean seeds with copper (Cu) can induce toxicity in seedlings depending on the applied dose and seed storage time after treatment. Silicon (Si) has the potential to mitigate Cu toxicity; however, the underlying mechanisms remain poorly understood. This study pr...

The success of dental implants in patients with systemic conditions. A retrospective clinical study

Background Systemic alterations are highly prevalent in the population and may interfere with peri-implant repair. Purpose The aim of this study was to investigate the association between systemic conditions with the loss of dental implants. Materials and methods This is a retros...

Bioactive Natural and Synthetic Chalcones: Brazil as a Research Powerhouse in Discovery and Innovation

Chalcones (1,3‐diphenyl‐2‐propen‐1‐one) are open‐chain flavonoids recognized for their structural diversity and broad pharmacological activities. Electrophilic α,β‐unsaturated carbonyl systems and versatile substitution patterns on aromatic rings have positioned the chalcones as...

Nutritional Status Enhances Honey Bee Colony Development and Soybean Yield, While Exposure to a Triple-Action Fungicide During Pollination Does Not Compromise Social Stability

Adequate nutrition is essential for honey bee colony development and may influence pollination services provided to agricultural crops. In contrast, fungicides commonly used in agriculture have been associated with physiological and behavioral alterations in individual bees, alth...

Effect of Combined Aerobic and Resistance Training on Exercise Capacity, Muscle Strength, Quality of Life, and Mortality in Patients with Coronary Heart Disease: A Systematic Review with Meta-analysis

CART (combined aerobic and resistance training) has shown important results in exercise-based cardiovascular rehabilitation. However, there are little data concerning the effects of CART on the exercise capacity, muscle strength, health-related quality of life (HRQoL), and mortal...

From Soil to Leaves: Decoding the Microbiome of Oil Palm in Colombia

Plant microbiomes are shaped by hierarchical ecological filters in which compartmentalization through the progressive selection of microbial communities along the soil-root-leaf continuum, emerges as the strongest structuring force. Despite the agronomic importance of oil palm (...

Association of breakfast frequency with blood pressure, waist circumference, physical activity, and sedentary behavior among Brazilian adolescents

To analyze the association of breakfast frequency with cardiovascular risk factors (blood pressure and waist circumference) and physical activity and sedentary behavior in adolescents. The sample consisted of 941 Brazilian adolescents (520 girls), aged 10–17 years. Anthropometric...

Estimation of Nodal Voltage Angles in Electrical Power Systems Using Artificial Neural Networks and Sensitivity Analysis of Input Variables

The estimation of nodal voltage angles is essential for the efficient and secure operation of electrical power systems. Traditionally, this estimation depends on the prior solution of the power flow problem, a procedure that may become computationally expensive in studies involvi...

Generative Artificial Intelligence Applied to Patient Safety and the Detection of Adverse Drug Events

Patient safety is one of the major challenges facing contemporary healthcare systems, requiring strategies capable of the early identification of risks and adverse events during healthcare delivery. Although electronic health records (EHRs) contain a large volume of clinical info...

Oral immunotherapy with anti-ES24 antibodies reduces burden and fecundity of Haemonchus contortus and inflammation in lambs artificially infected

Increasing multiple anthelmintic resistance in Haemonchus contortus has been reported worldwide, highlighting the need for alternative strategies to mitigate the damage caused by this nematode. In this study, we developed and evaluated an immunotherapy protocol based on specific...

Discontools supplement Mycoplasma hyopneumoniae infections in pigs: update and knowledge gaps

This manuscript reviews current knowledge on Mycoplasma hyopneumoniae , the primary agent of enzootic pneumonia in pigs, integrating advances in epidemiology, pathogenesis, immunity, diagnostics, and control. The pathogen is globally endemic, with transmission driven mainly by di...