Universidade de Brasília

Revisiting fully residually free Demushkin groups

Abstract We establish new examples and non-examples of pro- $$p$$ p limit groups among the class of Demushkin groups, that is, pro- $$p$$ p Poincaré duality groups of dimension $$2$$ 2 .

Traceability of Manilkara huberi Using Stable Isotope Ratio Analysis to Support Deforestation Prevention in the Amazon

Abstract Illegal deforestation represents one of the main challenges to the integrity of the Amazon rainforest, warranting the use of reliable tracking methods to identify the geographical origin of timber species inspected during commercial transactions. This study utilizes stab...

Healthcare occupancy data as an early warning indicator of infectious disease surges in São Paulo

Early detection of infectious disease surges is critical for effective public health response, yet traditional surveillance systems often suffer from delayed reporting. Here, we investigate whether passively collected occupancy data from healthcare facilities can act as an early...

Measuring Monetary Policy Coordination from Central Bankers’ Speeches

Abstract We propose a forward-looking measure of implicit international monetary policy coordination based on a dynamic similarity network of central bankers’ speeches. By analyzing speech transcripts from the Bank for International Settlements database, we show that this measure...

The impact of malnutrition on clinical outcomes in patients with perianal fistulizing Crohn's disease undergoing seton placement: A retrospective study

Abstract Background Perianal involvement occurs in up to 50% of patients with Crohn's disease (CD). Despite combined management, 10%–20% require fecal diversion or proctectomy. Nutritional status may influence prognosis, but its role in fistulizing perianal disease is unclear. Th...

Individual Differences in Self-Regulation Do Not Predict Firearm Skill Acquisition During Police Training: A Longitudinal Study of 205 Trainees

Police firearm training requires perceptual discrimination, decision-making, speed–accuracy control, and technical motor execution under institutional evaluation. This retrospective longitudinal study examined whether self-regulation-related psychological characteristics predicte...

Influence of osteoporosis on tissue repair promoted by different dental materials: an in vivo study in a rat model

Objectives: Osteoporosis is a prevalent metabolic disorder, and its impact on the biological response to dental materials is not fully understood. This study evaluated whether osteoporosis affects tissue repair promoted by MTA-Angelus (MTA) and an epoxy resin-based sealer contain...

Modeling double bounded data based on correlated gamma random variables

Abstract Many types of bounded data defined on the unit interval arise naturally as ratios of the form $$X/(X + Y)$$ . In the existing literature, the main statistical models proposed for this type of bounded data are typically based on the assumption that the random variables X...

The Value of Becoming Actual: Antinatalism, Cosmic Meaning, and Ontological Natal Permissibilism

Abstract David Benatar’s antinatalism holds that coming into existence is always a harm and that procreation is therefore morally impermissible. This article develops a non-theistic alternative to a recent supernaturalist response to Benatar offered by Wakeman and Launonen. It de...

Implications of self-medication among socially vulnerable older adults in the COVID-19 era (2021–2023)

Self-medication is a public health issue, exacerbated by limited healthcare access and the search for quick relief. In Brazil, resource shortages and the COVID-19 pandemic have intensified this behavior, leading to the indiscriminate use of medications among older adults in socia...

Fine-scale habitat quality drives isotopic niche variation in a didelphid opossum in fragmented semideciduous dry forests of central Brazil

Studies on the effects of habitat fragmentation on animal trophic ecology have traditionally emphasised patch size or habitat loss, while the role of habitat quality has been comparatively overlooked. We investigated how habitat quality – assessed through as fine-scale variation...

Experimental assessment of column rectangularity in flat‐slab slab–column connections

Abstract This paper presents an experimental investigation of the punching shear behavior of seven 3.00 m × 3.00 m × 0.20 m flat slabs without shear reinforcement, supported by internal rectangular columns. The column side lengths were varied to obtain aspect ratios, c max / c mi...

Note on principles of the three-body problem in gravitation and Lagrangian points

The three-body problem in gravitation is one of the oldest problems in celestial mechanics, having beenstudied since the end of the 18th century. Although there is no general closed-form solution to this problem,its analysis based on simplifications– as done by Lagrange and Euler...

Note on principles of the three-body problem in gravitation and Lagrangian points

The three-body problem in gravitation is one of the oldest problems in celestial mechanics, having beenstudied since the end of the 18th century. Although there is no general closed-form solution to this problem,its analysis based on simplifications– as done by Lagrange and Euler...

Rapid Eco-AI CE–MS Enables Sub-7 Min Low-Input Proteome Profiling with Quantitative Validation

Abstract Low-input and single-cell proteomics by mass spectrometry (MS) have advanced rapidly, but balancing analytical speed and sensitivity remains challenging, especially for small, protein-scarce primary cells such as neutrophils. Here, we report Rapid Eco–AI, an optimized el...

Evolution of striking dominance in Ultimate Fighting Championship: A cross-temporal analysis of factors associated with victory

This study examined the evolution of action frequencies associated with victory in UFC bouts across three distinct eras (2003–2004, 2013–2014, and 2023–2024). A total of 1722 fights were analyzed: Early Era (2003–2004; n = 77), Transition Era (2013–2014; n = 813), and Modern Era...

Gene therapy benefits in a small cohort of symptomatic 5q spinal muscular atrophy patients and real world pediatric outcomes

OBJECTIVE: To characterize clinical outcomes of gene replacement therapy administered after symptom onset in a small group of children with 5q spinal muscular atrophy (SMA) and to describe its impact on motor function and supportive care needs in real-world practice. METHODS: Obs...

Molecular modeling and quantum chemical calculation study of derived peptides from a Bowman-Birk inhibitor in complexes with trypsin

Abstract Context Bowman-Birk inhibitors (BBIs) are cysteine-rich proteins that inhibit trypsin and chymotrypsin proteases. Derived from soybeans, these natural BBIs have been identified as potential anticarcinogenic agents. Recent studies of the black-eyed pea trypsin/chymotrypsi...

Bioethical parameters for judicial decision-making in public health emergencies: a normative framework derived from COVID-19 health judicialization in Brazil

Abstract Background Health judicialization intensified during the COVID-19 pandemic in Brazil, placing courts at the centre of disputes over resource allocation, access to treatment, vaccination mandates, and intergovernmental health governance. Although bioethical frameworks for...

A mixed methods mapping of managerial competencies for hospital healthcare managers: implications for performance management and workforce development in a private Brazilian hospital

Abstract Background Managerial competencies shape how hospitals plan, execute and evaluate care processes, and in this study performance management is understood as the organizational cycle of planning, monitoring, evaluating and developing individual and team performance, wherea...