Universidad del Rosario

Effect of Glutathione S‐Transferase and Metallothionein Polymorphisms on Mercury Levels and End‐Stage Renal Disease ( ESRD ) in Colombian Patients

ABSTRACT Epidemiological studies have demonstrated a link between chronic kidney disease (CKD) and environmental mercury (Hg) exposure. Colombia has a well‐documented history of artisanal and small‐scale gold mining, where Hg exposure affects miners and nearby riverside and urban...

Rapidly Progressive Dedifferentiated Liposarcoma of the Spermatic Cord: A Case Report

Dedifferentiated liposarcoma (DDLPS) of the spermatic cord is an exceptionally rare and aggressive malignancy for which diagnostic and therapeutic guidelines remain limited. We report the case of a 73-year-old man who presented with a rapidly enlarging left inguinal/paratesticula...

Community views of factors influencing participation in dengue research: Fuzzy cognitive mapping in Dhaka, Bangladesh

Background Bangladesh is among the countries most affected by dengue, the fastest spreading vector-borne disease worldwide. Engaging communities in designing and implementing solutions is a promising strategy for dengue control. However, collaborating with communities in urban se...

Cardiovascular and psycho-emotional changes among completers of a medical student cohort with high loss to follow-up

Abstract Background Medical students are exposed to academic and lifestyle factors that may adversely affect cardiovascular and psycho-emotional health. Although these outcomes have been widely studied, most evidence is cross-sectional, and longitudinal evidence from Latin Americ...

Comparative Effectiveness Research in the Americas on Penetrating Brain Injury: The COMPAS-PBI Study Protocol.

BACKGROUND AND OBJECTIVES: Penetrating brain injury (PBI) is a highly lethal form of traumatic brain injury, with substantial mortality and marked differences across high-income countries and low- to middle-income countries. The aim of the Comparative Effectiveness Research in th...

Cajal the artist. The origins of a passion

Santiago Ramón y Cajal is widely recognized as the father of modern neuroscience. However, his life has many extraordinary facets, and he is even considered a polymath. Among his many activities, his artistic endeavors stand out, and this article focuses on exploring the origins...

Resisting ‘Nice Development’ in Latin America

Abstract This special issue focuses on forms of resistance to dominant development discourses and practices in Latin America. The attention is on the processes and practices through which grassroot groups challenge the capacity of official legal orders to recognise and address th...

Metatranscriptomic insights into mosquitoes and sand flies from Colombia reveal extensive virome variability and detection of bacterial and viral-related resistomes

Mosquitoes and sand flies are primary vectors of a wide range of pathogenic microorganisms that affect human and animal health worldwide. Their microbial communities directly affect their vector capacity and have become a focus of research for the development of novel biocontrol...

Antiproteinuric Response to Finerenone in Diabetic Kidney Disease: Responder and Non-Responder Subgroup Analysis of the FINDKDLATAM Study

Background/Objectives: Albuminuria is an early marker of kidney damage and an independent predictor of adverse outcomes, making its reduction a key therapeutic goal. Finerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, has demonstrated renal and cardiovascu...

Data capture, collection, management, and storage systems for clinical research: A scoping review protocol

The boom and constant transformation of biomedical research have led to the development of different electronic systems or platforms that allow researchers to respond to market demands and clinical research governance. The objective of this scoping review is to map and synthesize...

First Isolation of Candida parapsilosis from Water-Related Domestic Environments in Colombia: A Public Health Concern?

Background: Candida parapsilosis is an opportunistic yeast of increasing clinical importance, with fluconazole resistance rates rising globally and reaching concerning levels in clinical settings across several countries, including Colombia. However, the occurrence of antifungal-...

Giant intraparotid hemangioma presenting with facial nerve palsy in an adult: a rare case report of successful surgical excision and sural nerve graft reconstruction

Vascular anomalies of the parotid gland, particularly venous malformations presenting in adult populations, are rare entities that pose significant diagnostic and therapeutic challenges due to their infiltrative nature and proximity to vital neurovascular structures. While vascul...

Progressive Structural Failure in Complex Prosthetic Joint Infection Followed by Amputation

Background: Prosthetic joint infections (PJI) are complex complications of arthroplasty. Detailed sequential polymicrobial infection during long clinical courses, with multiple interventions and sustained antibiotic pressure, has been described sparingly. Methods: We present a ca...

Environmental drivers shape soil mite communities along succession, with limited links to litter decomposition in upper Andean tropical forests

Abstract Mite composition varied among sites but was stable between wet and dry seasons. Succession altered mite composition but not abundance or richness. Microclimatic and edaphic factors drive mite communities, with group specific responses. Few associations between mites and...

Time to first recurrent thrombosis in adults with thrombotic antiphospholipid syndrome: a registry-based retrospective cohort study

OBJECTIVE: To estimate time to first recurrent thrombosis and to explore the association between recurrent thrombosis and clinical, laboratory/immunological, and treatment-related factors among Colombian adults with thrombotic antiphospholipid syndrome (APS) enrolled in the ARTME...

The World Psychiatric Association (WPA) Guideline on Schizophrenia Spectrum Disorders Management for Low- and Middle-Income Countries

There is a pressing need to address the unique challenges of managing Schizophrenia Spectrum Disorders (SSD) in Low- and Middle-Income Countries (LMICs), where mental health resources are scarce and unevenly distributed. To develop this evidence-based guideline, we conducted a sy...

Clinical characterization in a population of latin-American older adults using the frontotemporal dementia assessment scale: an observational study

Abstract Background Aging is associated with gradual changes in cognitive, functional, and behavioral domains that may affect everyday functioning in older adults. In Latin America, these these functional and behavioral variations are frequently underrecognized in community setti...