Universidad de Sevilla

Genomic and clinical landscape of RAS mutations in acute myeloid leukemia

RAS mutations are recurrent in acute myeloid leukemia (AML); yet, their genomic and clinical landscape remain poorly characterized. We analyzed centralized molecular profiling data in 8,553 patients with newly diagnosed AML. Of these, 1,775 (21%) harbored RAS mutations: NRAS in 1...

A conceptual biocultural indicator framework for biodiversity in cultural landscapes: development and application in the Alhambra-Generalife-Albaicín (Spain) and Connemara (Ireland)

Abstract This paper develops a framework for the identification of biocultural indicators of biodiversity in cultural landscapes. To combat the persisting separation and dualistic conceptualisation of nature and culture in the heritage field, the framework views landscapes as dyn...

Engineering the Optical and Dielectric Performance of PVP / PS Blend Films via SiC / PbO 2 Nanofiller Hybridization for Flexible Electronic Applications

ABSTRACT This study investigates the fabrication and characterization of novel hybrid nanocomposite films based on a polyvinylpyrrolidone (PVP)/polystyrene (PS) blend reinforced with silicon carbide (SiC)/lead dioxide (PbO 2 ) nanostructures. X‐ray diffraction (XRD) analysis conf...

Hospital-linked and community-based viral hepatitis screening among Romanian migrants in Seville: A feasibility study

Introduction Romanian migrants may be at increased risk of viral hepatitis because many originate from countries with intermediate or high endemicity. Targeted, culturally adapted screening strategies are therefore needed to improve case finding and prevention. Our aim was to exp...

Research on Multi-Time-Scale Optimal Scheduling of Hydro–Solar Complementation in the Shuoqu River Basin

The integration of high shares of renewable energy into the power grid poses significant challenges to the stable operation of power systems. Hydropower, owing to its rapid response capability and reservoir regulation capacity, can effectively mitigate the volatility and randomne...

An ‘Empty’ [Fe 16 ] Cage and its Transformation into [Fe 17 ] and [Fe 30 ]

ABSTRACT Polymetallic clusters of Fe III constructed without organic bridging ligands are an emerging class of molecules with structures akin to iron oxide minerals, possessing large spin ground states and/or displaying spin frustration effects. All previous examples, [Fe 8 ], [F...

Replication package for "AI, Structural Power and Governance Fragmentation: A Systematic Review and the Geopolitical AI Power Framework"

Replication package for a PRISMA 2020 systematic review on artificial intelligence and structural power in the global political economy. It contains the exact Scopus and Web of Science queries (5 October 2026) and record counts per stage; the screening decisions for 1,199 dedupli...

Modal Identification of a Superimposed Structure: The Crossing of the Mosque–Cathedral of Córdoba

The Gothic–Renaissance crossing of the Mosque–Cathedral of Córdoba constitutes one of the most structurally complex sectors of the monument owing to the coexistence of Islamic and Christian construction systems developed over several centuries. Accurately reproducing the mechanic...

Artificial intelligence as enabler and object of strategic foresight: a theoretical framework for digital organisational transformation

Purpose Research on artificial intelligence (AI) in organisations has concentrated on operational efficiency and automation. This study aims to reposition AI as both a constitutive element and a strategic object of foresight, a dual role the literature has noticed but not theoris...

Occurrence of benzophenones and poly- and perfluoroalkyl substances in raw sheep wool from predominantly rural regions without major industrial centers

Abstract Background Poly- and perfluoroalkyl substances (PFAS) and benzophenones (BPs) are widely utilized industrial chemicals recognized as endocrine-disrupting chemicals (EDCs). While their environmental ubiquity and adverse effects on biota are well-documented, the extent of...

Evidence-based atlas of risk and protective factors for psychotic disorders: an umbrella review to inform personalized prognosis and prevention.

Identifying updated, evidence-based risk and protective factors for psychotic disorders is essential to advancing scientific and clinical knowledge of their etiology. Since the most recent umbrella review published in this journal, the evidence base has expanded substantially. Fo...

Using BDF Schemes in the Temporal Integration of POD-ROM Methods

Abstract In this paper we consider the numerical approximation of a semilinear reaction-diffusion model problem by means of reduced-order methods (ROMs) based on proper orthogonal decomposition (POD). We focus on the time integration of the fully discrete reduced-order model. Mos...

Super-Twisting Sliding Mode Control for Single-Stage Isolated Bidirectional V2G Chargers

Vehicle-to-grid (V2G) technology plays a critical role in modern power systems by utilizing electric vehicles as distributed energy storage to smooth power fluctuations and achieve peak-shaving and valley-filling. As a vital power electronics interface, single-stage isolated bidi...

EndoWake: Modeling Wind by Linear Programming for Wind Farm Layout Optimization

The Wind Farm Layout Optimization problem consists of placing a given number of turbines within a given area so as to maximize energy production. One of its main challenges is the wake effect between turbines, which can strongly affect production and is a cumbersome function to e...

EndoWake: Modeling Wind by Linear Programming for Wind Farm Layout Optimization

The Wind Farm Layout Optimization problem consists of placing a given number of turbines within a given area so as to maximize energy production. One of its main challenges is the wake effect between turbines, which can strongly affect production and is a cumbersome function to e...

Long-term effects of regional shocks on new opportunity and necessity entrepreneurship

The dynamics of start-up activity are crucial for regional development. Does regional firm formation exhibit hysteresis, such that shocks, including temporary policy interventions, have permanent effects? We distinguish between entrepreneurs pulled by opportunity and those pushed...

Development of a New Bioadhesive Gel in the Prevention of Bacterial Biofilms on Dental Implants: An In Vitro Study

ABSTRACT Objectives Peri‐implantitis is a reality that clinicians face in their daily practice. Current evidence discusses the applicability of bacteriostatic or bactericidal methods in order to minimize the colonization of bacteria, which entails controversy. In this scenario th...

Concentration levels of benzophenones in raw sheep’s wool

Benzophenones (BPs) are widely utilized across various industrial sectors, leading to environmental contamination and bioaccumulation in living organisms, where they act as endocrine disruptors. Despite their ubiquity, data regarding BP exposure in livestock remain remarkably sca...

Improvements of Relative Indicators of Trunk Diameter Fluctuations in Comparison to Discrete Indicators in the Regulated Deficit Irrigation Scheduling of Olive Trees

Daily cycles of trunk fluctuations are used to measure plant water status. However, the traditional indicators derived from these curves constrains the selection of thresholds. The aim of this work was to evaluate a new indicator based on maximum daily shrinkage (MDS). The experi...

When populism meets artificial intelligence: AI-generated multimedia content and far-right digital campaigning on Instagram and X in the 2024 European elections

Europe is witnessing an unprecedented rise in far-right populism. Since 2018, the growing political representation of populist leaders, parties, and governments in European institutions has intensified the circulation of disinformation, a phenomenon that became particularly visib...