Universidad de Oviedo

FAβ-gal: an automated fluorescence-based quantification of the senescence-associated beta-galactosidase X-gal assay

Abstract Cellular senescence plays a pivotal role in aging and cancer, two major biomedical and socioeconomic challenges of our time. Therefore, its study has become crucial for the design of interventions based on its manipulation. In this sense, researchers have developed a wid...

Microplastics in porifera: a systematic review

Marine sponges (Phylum Porifera) are ecologically key filter feeders playing central roles in water purification and habitat structuring across all latitudes. Their filter-feeding behaviour and established use as bioindicators of chemical pollution make them strong candidates for...

Type II embeddings for d = 6 Einstein-Maxwell gauged supergravity

A bstract Bi-spinor and G-structure methods are used to classify the possible consistent truncations of type II supergravity to d = 6 Einstein-Maxwell (gauged) supergravity, and its consistent sub-sectors. In the absence of R-symmetry gauging and a tensor multiplet we establish t...

Estimating the gender wage gap using stochastic frontiers: some modelling issues

Purpose The purpose of this study is to analyse the gender wage gap in Italy by adopting a Stochastic Frontier Approach, with the aim of assessing whether gender differences persist after controlling for individual and job-related characteristics and how modelling choices affect...

Classification of Seasonal Allergic Rhinitis Patients by Prospective Patient‐Recorded Symptoms: The @ IT .2020 Project

BACKGROUND: Seasonal allergic rhinitis (SAR) has been so far classified according to frequency and severity by retrospective information based on the ARIA (Allergic Rhinitis and its Impact on Asthma) classification. Electronic symptom diaries (e-Diaries) are feasible tools to col...

Tisa-cel and axi-cel CAR structure influences the development of resistance to CD19-CAR-T therapy

CD19-CAR-T cells are a major therapy for relapsed/refractory B-cell malignancies, yet ~50% of patients relapse after infusion. Clinical data suggest that tisa-cel treatment is associated with higher rates of CD19 mutation than axi-cel, though direct comparisons have been lacking....

Reframing clinical reasoning in Pediatric nursing education: A case-based socio-clinical model for family-Centered care

BACKGROUND: Undergraduate pediatric nursing education must prepare students to integrate clinical information with developmental interpretation, family perspectives, communication, and uncertainty. Although case-based learning supports knowledge application, its conventional fram...

Update on Perioperative Prevention of Cardiac Surgery-Associated Acute Kidney Injury

Cardiac surgery-associated acute kidney injury (CS-AKI) increases short- and long-term mortality, progression to chronic kidney disease (CKD), and healthcare costs. Its pathogenesis is multifactorial—combining renal hypoperfusion, impaired oxygen delivery, hemodilution, inflammat...

Vignettes and triadic games: Novel approaches to assess students’ declarative knowledge in physical education

The emergence of Teaching Games for Understanding aimed to promote a shift from teacher-centred to student-centred learning frameworks. The Tactical Games Model, a simplified version, aims to create players who are both technically and tactically intelligent. Triadic games are a...

Does increased staging complexity influence expert agreement in dental age estimation?

Dental age estimation (DAE) is a well-established procedure in current practice, and it is frequently required in forensic and legal investigations. This study aimed to evaluate the intra- and inter-observer reliability of dental development staging among forensic practitioners u...

Factors Associated with Smoking Status and Self-Reported Physical Activity Among Spanish Nursing Professionals: A Cross-Sectional Study

Background: Modifiable lifestyle behaviours, including physical activity and smoking, are important determinants of health and may influence the mental well-being of nursing professionals. However, evidence simultaneously examining these factors and their associations with sociod...

Policy Consequentiality in Tourism Discrete Choice Experiments

Stated preference methods are widely applied in tourism research, yet their validity depends on respondents perceiving surveys as policy consequential. This paper examines how such perceptions shape willingness-to-pay (WTP) estimates for redesigned tourism supply. Using a discret...

Microscopic screening theory for excitons in two-dimensional materials: a bridge between effective models and ab initio descriptions

We present a computational approach for exciton calculations in two-dimensional (2D) materials within the Bethe–Salpeter equation (BSE) framework, employing an atomistic description with point-like orbitals. Unlike widespread efficient calculations that rely on classical or effec...

Nanotechnology-Enabled Remediation of Contaminated Soils: Mechanisms, Soil Constraints, Environmental Risks, and Implications for Sustainable Land Management

Engineered nanomaterials have been increasingly proposed for the treatment of contaminated soils. Nevertheless, most available evidence has been obtained in water, artificial substrates or short-term laboratory experiments, and performance in real soil is substantially more varia...

A dual role for miR-210-3p in hypoxia-driven signaling and mitotic regulation in cancer

miR-210-3p is a well-established hypoxia-induced microRNA that is commonly upregulated in a wide range of solid tumors, traditionally linked to mitochondrial repression and hypoxia-inducible factor (HIF) signaling. However, its functional role in cancer remains complex and highly...

A narrative review of determinants consequences, and public health implications of vaccine hesitancy in Nigeria

Vaccine hesitancy remains a significant barrier to achieving optimal immunisation coverage in Nigeria, contributing to recurrent outbreaks of vaccine-preventable diseases and limiting progress towards national and global public health goals. This narrative review synthesises rece...

Non-communicable disease care delivered by emergency medical teams during the Gaza Health Response in 2024–2025: an observational analysis of WHO Minimum Data Set Reports

The objective is to describe patterns of noncommunicable disease (NCD) service delivery and the operational roles of the different Emergency Medical Team (EMT) types-Type1 mobile (outpatient mobile primary care), Type1 fixed (outpatient static primary care), and Type2 (inpatient...

Recreational versus self-medicated cannabis use among adolescents and young adults in Spain: associations with substance use and mental health

Abstract Background Cannabis use is common among adolescents and young adults, yet motives, especially self-medication, remain poorly understood in non-legalized contexts. This study explored differences among recreational, self-medicated, and dual (recreational + self-medicated)...

When Care Does Not Count: Epistemic Injustice and the Organisational Recognition of Nursing Knowledge

This discussion paper examines how care-based nursing judgement becomes recognised, narrowed or excluded as professional knowledge within healthcare organisations. Nursing care is often described as relational, ethical, practical or compassionate, yet these descriptions may obscu...

Barriers and facilitators to advance care planning implementation: a qualitative interprofessional study in the Spanish public health and social care system

Advance Care Planning (ACP) is essential for improving the quality of end-of-life care. Despite having a well-established legal framework, the implementation of ACP in Spain is limited and largely bureaucratic. The existing literature has primarily focused on knowledge deficits a...