Universidad de la República de Uruguay

Ensuring pragmatic and equitable paths forward for hepatitis B virus infection eradication in Latin America

INTRODUCTION: Latin America occupies a paradoxical position in hepatitis B virus (HBV) elimination: aggregate prevalence is low, yet the region remains far from the WHO and PAHO 2030 targets because the burden is structurally concealed within underserved populations and fragmente...

An Enhanced Projection Pursuit Tree Classifier with Visual Methods for Assessing Algorithmic Improvements

This paper presents enhancements to the projection pursuit tree classifier and visual diagnostic methods for assessing their impact in high dimensions. The original algorithm uses linear combinations of variables in a tree structure where depth is constrained to be less than the...

Synthesis and Antiparasitic Activities of New Organometallic Derivatives of the Benzimidazole Anthelmintic Drugs

About 50 years after their development, the benzimidazole anthelmintic drugs still occupy a key role in the treatment of parasitic diseases. Like other anti-infective drugs, their extensive use has led to resistance development and now requires new solutions to treat these diseas...

Emotional Dynamics as a Transdiagnostic Factor Associated With Internalizing Problems in Emerging Adults

Emotion regulation difficulties are closely linked to internalizing problems, yet few studies have examined both regulation strategies and affective dynamics simultaneously, particularly among emerging adults in Global South contexts. This study examined associations among emotio...