Universidad Bernardo O'Higgins

Waterborne gill-toxic potency as an effect-based endpoint for monitoring fish-killing harmful algal blooms

Abstract Fish-killing harmful algal blooms (HABs) continue to inflict severe economic losses on marine aquaculture worldwide, yet monitoring systems designed around microalgal cell counts frequently fail to anticipate acute mortality events. The dominant surveillance paradigm was...

Conflict or uncertainty? Reading the partial paraconsistency hierarchy of interval (T, I, N, U₁, …, Uₙ, F) tuples from language-model outputs

Genuine conflict (truth and falsity both strongly supported) and plain uncertainty (weak support either way) are different epistemic situations, yet a single probability of truth reports both as the same kind of number. This feasibility study populates the partial paraconsistency...

Landmark-defined two-dimensional lung configuration in women with osteogenesis imperfecta type III: an exploratory geometric morphometric pilot study

Osteogenesis imperfecta (OI) type III is a rare disorder in which severe thoracic deformity may alter pulmonary anatomy. This exploratory pilot study assessed whether the relative two-dimensional configuration of four reproducible pulmonary landmarks differs between adult women w...

Typed Indeterminacy Engineering: A Practitioner's Design Pattern for Carrying Uncertainty Types Through a Decision Pipeline

Decision systems that operate under uncertainty — LLM-as-judge evaluators, multi-criteria ranking procedures, evidence-fusion pipelines, AI alignment mechanisms, expert-consensus methods — routinely reduce heterogeneous epistemic failure modes to a single scalar of “confidence.”...

Modeling Financial Structural Dynamics Under Uncertainty: A Neutrosophic-Score Dual STATIS Approach for Cooperative Financial Systems

This study extends the existing Neutrosophic STATIS framework toward the dual analysis of relationships among financial variables observed over multiple periods. Financial uncertainty was operationalized as modeled indeterminacy derived from local temporal volatility and deviatio...

Andrographolide: Mechanisms and Therapeutic Potential in Alzheimer’s and Parkinson’s Disease

Neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) are characterized by the progressive loss of specific neuronal cell populations and are associated with protein aggregates. Current therapeutic approaches are still limited due to the complex...

Electoral results affect beliefs about the past: Evidence from Chile

Can electoral outcomes shape voters' perceptions of the past? We argue that electoral outcomes provide informational cues that prompt voters to reinterpret prior conditions, shifting the benchmarks on which accountability rests. We focus on perceptions of crime, a valence issue t...

Chile-ED-Resp: A Curated and Reproducible Weekly Hospital Dataset for Respiratory Emergency-Demand Forecasting in Chile

Respiratory emergencies create recurrent seasonal pressure on hospital services, yet reproducible forecasting research is often hindered by the effort required to retrieve, interpret, harmonize, and document public administrative data. Chile-ED-Resp is a curated secondary dataset...

Effect of Freeze Concentration on the Process Parameters, Physicochemical Properties, Total Bioactive Compounds and Antioxidant Capacity of Almond Milk

The objective of this study was to evaluate the application of centrifugal block freeze concentration (CBFC) in fresh almond milk to obtain a concentrated liquid sample with enhanced chemical composition, total bioactive compounds (TBC), antioxidant activity, and process paramete...

External Mechanical Workload and Acute Physiological Responses During Intermittent Normobaric Hypoxia in Elite Cyclists

Background: Intermittent normobaric hypoxia (INH) has been proposed as a strategy to increase physiological stress while maintaining a relatively low external mechanical workload. However, the acute physiological responses elicited during standardized INH combined with low-intens...

Molecular overview of major salivary gland carcinomas in chilean patients: 2 case reports

Abstract Background Salivary gland tumors (SGTs) are rare neoplasms that account for 8.5 % of head and neck cancers and comprise a highly heterogeneous group of benign and malignant subtypes, according to the World Health Organization. In Chile, epidemiological and molecular data...

Complete mitogenome of Pelecorhynchus vulpes (Macquart) (Diptera: Pelecorhynchidae) and its phylogenetics implications on Tabanomorpha

The infraorder Tabanomorpha represents a key lineage within the lower Brachycera; however, the phylogenetic placement of several families, including Pelecorhynchidae, remains incompletely resolved owing to the lack of mitogenomic data. In this study, we sequenced and characterize...

Effects of Zinc Supplementation on Glycemic Control, Insulin Resistance, Inflammation and Oxidative Stress in Diabetes: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

ABSTRACT Objectives Diabetes mellitus (DM) is a chronic metabolic disorder characterized by insulin resistance, impaired insulin secretion, and increased cardiometabolic and inflammatory burden. Zinc plays a key biological role in insulin synthesis, storage, signalling and antiox...

Strategic responses to digital disruption: lessons from online business education in Chile

Purpose This paper provides a strategic and capability-based longitudinal analysis of the evolution of online undergraduate business education in Chile between 2012 and 2024. Rather than treating digital expansion as a purely technological shift, this study aims to examine how bu...

Impact of Spatial Knowledge on Fire Evacuation Performance in Large Buildings: An Integrated Simulation Approach

This study examines human evacuation performance in complex building environments under highly uncertain fire conditions, with a focus on how spatial knowledge and decision-making strategies influence exposure to hazardous conditions during emergencies in smart building contexts....

Prevalence of Persistent Left Superior Vena Cava in Patients with Congenital Heart Disease: A Systematic Review with Meta-Analysis

Persistent left superior vena cava (PLSVC) is the most frequently reported anatomical variant of the thoracic systemic venous system. While its association with congenital heart disease (CHD) is well recognized, its prevalence within CHD populations and its relative occurrence co...