Institution
Trinity College Dublin
Recent research
- Health & Medicine
Abstract Topic Esophageal Cancer: Barrett‘s Esophagus: High-Grade Dysplasia and Early Invasive Cancer Background In many European countries, esophageal adenocarcinoma (EAC) incidence is increasing [1]. Barrett’s esophagus(BE), strongly associated with EAC, can progress via dyspla...
- Health & MedicineOpen access
“Clinical placement logbooks: how do they shape medical student learning behaviours?”
Abstract Background Clinical placement logbooks are widely used to guide learning, document clinical exposure, and support student–tutor feedback. Despite their ubiquity, little is known about how logbooks shape medical students’ learning behaviours, particularly the tension betw...
- Health & Medicine
A retired consultant gastroenterologist, Professor Seamus O’Mahony trained as a doctor in Ireland, before continuing his career in the UK National Health Service (NHS). Later returning to his nativ...
- Health & Medicine
Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Prehabilitation, involving preoperative exercise, nutrition, and psychological support, aims to optimise patients prior to major surgery. Their impact on patien...
- Climate & EnvironmentOpen access
Celestial amplitudes on electromagnetic backgrounds: T-duality from S-duality
Abstract What is the boundary holographic dual of S-duality for gauge theories in asymptotically flat space-times? Celestial amplitudes, by virtue of exhibiting holographic properties of the S-matrix, appear well-suited for studying this question. We scatter electrically and magn...
- AI & ComputingOpen access
dynoGP: Deep Gaussian Processes for Dynamic System Identification
ABSTRACT In this work, we present a novel approach to system identification for dynamical systems, based on a specific class of deep Gaussian processes (deepGPs). These models are constructed by interconnecting linear dynamic GPs (equivalent to stochastic linear time‐invariant dy...
- Health & MedicineOpen access
Background Drug-eluting bead transarterial chemoembolization (deb-TACE) is a standard for liver-limited, locally advanced hepatocellular carcinoma (HCC) and may enhance response to immune checkpoint inhibition through tumor immune microenvironment modulation. We evaluated nivolum...
- Climate & EnvironmentOpen access
Domestic on-site wastewater treatment systems (OWTSs) are configured with a variety of treatment technologies, resulting in varying degrees of effluent pre-treatment before the effluent is distributed into the soil for percolation via the soil treatment unit (STU), more usually k...
- Health & MedicineOpen access
Adolescence and young adulthood is characterised by complex developmental and psychosocial changes. The diagnosis of a life-limiting condition adds complexity and stress to this already turbulent period of life. Provision of developmentally appropriate palliative care to this gro...
- Health & MedicineOpen access
Abstract Inhalable messenger RNA (mRNA) therapeutics are moving pulmonary drug delivery from local deposition of small molecules toward transient, programmable expression of antigens, secreted proteins, antibodies, gene-editing enzymes and replacement proteins directly within the...
- Society & EconomicsOpen access
Typology of transit-oriented development to promote sustainable urban structure
<title>Abstract</title> Transit-Oriented Development (TOD) has emerged as a transformative strategy in sustainable urban planning, aiming to integrate land use and public transportation to foster compact, walkable, and mixed-use communities centered around high-capacity transit s...
- Climate & Environment
The Middle Triassic (246−235 Ma) seawater 87Sr/86Sr record exhibits an excursion following the recovery from Siberian large igneous province volcanism. Two primary mechanisms have been proposed to explain the isotopic shift: (1) a change in the 87Sr/86Sr ratio of the continental...
- Materials & EnergyOpen access
ABSTRACT The chiral pda derived anisole ligands L1a [ 1( R,R )] and L1b [ 1( S,S )], along with their phenol derivatives L2a [ 2( R,R )] and L2b [ 2( S,S )], were used for lanthanide‐directed synthesis of their respective Tb(III) complexes. Under thermodynamic control, the 3:1 (l...
- BiologyOpen access
Background The Lancet Oncology Commission on cancer genomics and precision oncology identified workforce capability, education, and training as major constraints to equitable implementation. As genomic and multi-omic technologies become integrated into cancer care, structured app...
- BiologyOpen access
Heatwaves and cold snaps alter host-parasite population dynamics
Climate change is increasing the frequency and intensity of temperature extremes, yet the consequences of heatwaves and cold snaps for host-parasite interactions remain incompletely understood.Thermal pulses of ±6°C were experimentally tested to determine how disease dynamics are...
- Health & Medicine
Learning Domains for Undergraduate Dental Behaviour Support: The BeSiDe Curriculum Learning Outcomes
OBJECTIVES: Dental Behaviour Support (DBS) refers to informal and formal strategies and interventions that support patients' acceptance and experience of oral healthcare. DBS plays a crucial role, particularly for vulnerable groups, yet training across dental curricula remains in...
- Health & MedicineOpen access
Macrophages tune NK cell IFNγ production through direct lipid transfer
Abstract Natural killer (NK) cells are critical effectors of innate immunity, but their activity is strongly influenced by metabolic state. While intrinsic NK metabolism has been studied extensively, less is known about how surrounding immune cells shape NK cell function. Here, w...
- Climate & EnvironmentOpen access
Life cycle assessment shows that integrating nut trees reduces carbon footprint of soybean farming
Abstract Agroforestry systems enhance productivity, resource-use efficiency, and climate resilience, offering a promising pathway for integrating soybean ( Glycine max L. Merr.), European hazelnut ( Corylus avellana L.) and sweet chestnut ( Castanea sativa Mill.) into sustainable...
- Society & EconomicsOpen access
Why do some publics engage deeply with distant conflicts absent direct ethnic or strategic ties? Existing explanations emphasise geopolitical ties, demographics, or elite cues, but these cannot account for the Republic of Ireland’s consistent pro-Palestinian stance, exceptional i...
- Health & MedicineOpen access
Mapping basal ganglia circuitry in altered states of consciousness: from pathology to pharmacology
The precise neuromodulatory mechanisms underlying consciousness and its disorders, despite growing evidence in both animals and humans, remain poorly understood at the subcortical level. The basal ganglia, a key component of the cortico-basal ganglia-thalamo-cortical loop, are kn...