Tokyo University of Science

Synthesis and Characterization of Zinc Complexes with Diethyl 2-Hydroxyazulene-1,3-dicarboxylate as a Ligand

Abstract The reaction of diethyl 2-hydroxyazulene-1,3-dicarboxylate (DEHA) with zinc species (Zn(OAc)2 and ZnCl2) in the presence of various alkali metal carbonates (M2CO3) was investigated. The resulting complexes were characterized by nuclear magnetic resonance spectroscopy, Fo...

Enantio- and diastereoselective synthesis of multi-helical nanographenes

Nanographenes, composed of two-dimensionally fused planar polycyclic aromatics, are promising candidates for organic optoelectronic applications due to their high chemical and thermal stability and efficient charge transport. However, their high planarity often leads to aggregati...

Real-Time Monitoring with a Wristwatch-Type Sodium- and Potassium-Ion Sensor Using a Screen-Printed Liquid-Junction Reference Electrode

Abstract Wearable ion sensors have gained increasing attention for the continuous noninvasive monitoring of ions in body fluids such as sweat. However, printed reference electrodes commonly used in potentiometric ion sensors require prolonged conditioning to achieve stable potent...

Multidirectional Colossal Polarization in a Centrosymmetric Crystal via Long-Range Ion Displacement

Abstract Ferroelectrics exhibit spontaneous polarization and are highly functional materials that are widely used in various devices. However, the design of conventional ferroelectric compounds is largely limited to noncentrosymmetric, polar structures. Herein, we demonstrate tha...

Observation of near-infrared fluorescence from within biological specimens using X-ray light-sheet microscopy for deep-tissue imaging

Abstract Light-sheet fluorescence microscopy enables rapid three-dimensional imaging of biological specimens with low phototoxicity and high signal-to-noise ratio, but its imaging depth is limited by optical scattering and absorption in tissue. X-ray light-sheet microscopy, terme...

False Vacuum in Coupled-Frustrated Multi-Component Superconductors

A local minimum state, energetically inequivalent to the global minimum, can emerge in a coupled-frustrated multi-component superconductor. This local minimum state is metastable when it occupies the entire system. However, when a global-minimum domain appears within the metastab...

Lateralization of retinal structure correlated with behavioral lateralization in the oval squid Sepioteuthis lessoniana

Abstract Background Cephalopods, including Sepioteuthis lessoniana , preferentially orient either the left or right eye toward visual targets during various visually guided behaviors, as most of their visual field is monocular. Such visual lateralization is widely observed in the...

Plant defense activators for sustainable crop protection: a mechanism-based perspective on their regulatory positioning

The environmental and ecological costs of chemical pesticide use have intensified the search for alternative crop protection strategies. Among these, plant defense activators (PDAs) represent a distinct class of compounds that enhance plant resistance through activation or primin...

Community periodontal index based screening findings and healthcare expenditures: a 7-year cohort study of male employees in Japan

Abstract Background The global economic burden of dental diseases, particularly periodontitis, is substantial, with growing evidence linking these conditions to systemic diseases such as diabetes and cardiovascular diseases. Although international studies have demonstrated that p...

Thermoelectric and Magnetic Properties in Doped Fe 2 VAl Based on a Bipolar Random Anderson Model

We investigate the thermoelectric and magnetic properties of Si-substituted n-type and Ti-substituted p-type Heusler alloy Fe 2 VAl using the bipolar random Anderson model, which has been introduced recently to study antisite-defect effects associated with the sign change of the...

The parent bodies of Ryugu and Ivuna formed before those of other carbonaceous chondrites

Most carbonaceous chondrite (CC) meteorites contain abundant chondrules, millimeter-scale spherical inclusions of previously molten material. Ivuna-type carbonaceous chondrites (CIs) do not contain chondrules, nor do samples of the carbonaceous asteroid Ryugu. CIs and Ryugu share...

Phase-controlled null-space expansion for analog beamforming massive MIMO in high-mobility scenarios

Abstract This paper proposes a novel null-space expansion (NSE) scheme based on phase-only control to exploit the degrees of freedom of massive antenna elements even in analog beamformers. Downlink multi-user Multiple-Input Multiple-Output (MIMO) spatial multiplexing is performed...

Beyond [ N ]Phenylenes: Synthesis and Investigation of Linear [4] and [5]Naphthylenes Incorporating Multiple Four‐Membered Rings

ABSTRACT Ladder‐type polycyclic conjugated hydrocarbons (PCHs) incorporating four‐membered rings represent a unique class of organic materials with local antiaromaticity and dearomatization induced by the four‐membered rings. [ N ]Phenylenes represent the only systematically synt...

Association of adjustability of grasping force in dominant and nondominant hands with physical and cognitive function in community-dwelling older adults: a cross-sectional study

Abstract Background Adjustability of grasping force (AGF) is essential for activities of daily living (ADL) and instrumental ADL. However, its association with physical and cognitive functions in older adults, and whether these associations differ by hand remain unclear. Therefor...

Aging beyond older adults: Transdisciplinary perspectives on demographic change in Japan

Population aging is increasingly recognized not merely as a demographic phenomenon, but as a broader societal transformation reshaping care systems, labor structures, infrastructure, communication, governance, and everyday social relations. Using Japan as an example of an advance...

Positive selection of IgG over IgM plasma cells through BCR isotype–specific antigen presentation and signaling

During a primary immune response, B cells can undergo isotype switching from an immunoglobulin M (IgM) B cell receptor (BCR) to an IgG BCR. B cells that have switched to IgG give rise to more bone marrow long-lived plasma cells (PCs) compared with those expressing IgM, but how BC...

Maxwell’s Demon in Markov Chain Monte Carlo: Cooling Information Flow and Entropy Balance

Markov chain Monte Carlo algorithms can be viewed as feedback devices that compare a proposed move with the target distribution and then accept or reject it. In this paper the Maxwell demon is identified with the acceptance module: it measures a proposed edge, stores the outcome...

Characterisation of a human monoclonal antibody targeting a conserved epitope at the base of the HA head of influenza A(H3N2) virus

Background Numerous broadly reactive human monoclonal antibodies (mAbs) against the haemagglutinin (HA) of influenza A viruses have recognised conserved epitopes across HA subtypes or within subtypes. Most heterosubtypic mAbs target the HA stem, the receptor-binding site (RBS), o...

Surface protein profiling reveals depot-specific features of subcutaneous and visceral adipose progenitor cells

SUMMARY White adipose tissue is organized into anatomically and functionally distinct depots, yet the mechanisms by which intrinsic differences between subcutaneous and visceral adipose progenitor cells (APCs) contribute to depot-specific inflammatory and remodeling properties re...

Fatigue behavior of ultrasonically welded CF/PPS single-lap joints compared with bulk PPS using entropy-based finite element analysis

In this study, carbon-fiber-reinforced polyphenylene sulfide (CF/PPS) laminates were joined by ultrasonic welding using a PPS interlayer to form single-lap joints, and their temperature-dependent fatigue behavior was investigated within an entropy-based fracture framework. A fati...