Tokyo Metropolitan University

Pd(II)-Templated End-to-End Cyclization of Doubly N-Confused Bilatrienes: A Stable Singlet Diradicaloid Dye with Efficient Absorption across the Solar Spectrum

Abstract We report a highly stable singlet diradicaloid (Pd1-dimer), formed through a Pd(II)-templated end-to-end cyclization of a linear N-confused bilatriene (1). This unique Pd-bridged double-loop complex exhibits an open-shell singlet diradicaloid ground state with an extreme...

Distribution based design framework for ultrasonic process intensification using effective acoustic intensity

Abstract Ultrasonic processes are widely applied for dispersion and structural transformation of layered materials. In such processes, performance is often evaluated based on total input energy. However, because the acoustic pressure field in a liquid medium is inherently spatial...

Engineering Anaerobic Metabolic Branch Points to Control Carbon Allocation Between Wax Ester Synthesis and Succinate Accumulation in Euglena gracilis

ABSTRACT Under anaerobic conditions, Euglena gracilis degrades paramylon and synthesizes wax esters (WEs) while accumulating succinate in the culture supernatant. Succinate can either be converted to succinyl‐CoA by succinyl‐CoA synthetase (SCS) and enter the propionyl‐CoA biosyn...

Keep the Runtime, Derive the JIT Compiler: Runtime-Preserving Meta-Tracing with Two Coexisting Garbage Collectors

Meta-tracing frameworks derive a tracing JIT compiler from an interpreter, but implementations built with them commonly reimplement the object model and core library of an existing runtime as well. Meta-tracing constrains only the interpreter, not the values it manipulates. In ru...

Orbital Coupling Engineering through P-Block Metal Doping in NiFe Layered Double Hydroxides for Enhanced Anion-Exchange Membrane Water Electrolysis

Abstract The oxygen evolution reaction (OER) remains a major kinetic bottleneck in anodic water splitting because of sluggish adsorption and desorption kinetics of O-containing intermediates. Optimizing the adsorption strength of various O-containing intermediates in accordance w...

Selective Decarbonylative Bromination of Aromatic Aldehydes Enabled by Ensemble-Engineered Au–Pd Alloy Nanoparticle Catalysts

Abstract Bromoarenes are important structural motifs across a wide range of chemical fields and serve as versatile synthetic intermediates. However, the direct synthesis of bromoarenes from ubiquitous and readily available aldehydes has remained challenging. Herein, we report the...

Modeling long-term and interannual crop area changes: Integrating socioeconomic and hydrometeorological factors in the Indus Basin

Water management is critical for policymakers in agriculture-dominated regions, where water demand and withdrawals change in response to variations in crop area, such as in the Indus River Basin (IRB). However, the mechanisms driving long-term and interannual crop area changes, p...

A Residue-Resolved Mechanism for Trapped-Twist Spectral Tuning in Cyanobacteriochromes

Abstract Cyanobacteriochromes (CBCRs) are bilin-binding photoreceptors that photoconvert between long-lived, thermally stable states; in the red/green subfamily, photoexcitation converts the red-absorbing Pr state to the green-absorbing Pg state with a large blue shift. Here we q...

Comprehensive profiling of brain dynamics during anesthesia across phylogeny

Abstract The behavioral effects of anesthetics are highly conserved across species, hinting at shared and fundamental underlying mechanisms. Here we compile a dataset of multiscale neural activity during wakefulness and anesthesia, encompassing human, macaque, marmoset, mouse, ze...

Evaluating a service-learning program: benefits of integrating medical students into school cancer education on teaching skills and cancer knowledge

Abstract Background Integrating medical students into school cancer education programs as service-learning is a promising strategy. This study assessed the impact of such programs and evaluated their effectiveness in improving students’ teaching self-efficacy and understanding of...

Systematic Evolution of Magnetic Anisotropy and Crystal-electric-field Ground States in Sm Tr 2 Ge 2

We investigated the crystal-electric-field (CEF) states in SmTr 2 Ge 2 (Tr = Co–Cu and Ag) with the ThCr 2 Si 2 -type structure by magnetization and specific heat measurements. The magnetic anisotropy evolves systematically with Tr, changing from an easy ab plane for Tr = Co and...

Strain Correlated Linearly Polarized Photoluminescence in WSe2/WS2 Moire Superlattices

Abstract Reliable optical control of valley degrees of freedom in moiré excitons requires that the emitted polarization faithfully reflects the underlying valley state. Here, we show that linearly polarized photoluminescence from WSe2/WS2 moiré excitons is largely insensitive t...

Association Between EEG Activity and Motor Imagery Ability in Single-Joint Movements: A Pilot Study

Background/Objectives: This exploratory pilot study examined whether motor imagery ability is associated with electroencephalography (EEG) oscillatory activity during single-joint motor imagery. Methods: Eleven healthy young adults performed motor execution, kinesthetic motor ima...

Modification Technology for Exosome Membranes using Membrane-Curvature-Sensing Peptides and Its Application to Boron Neutron Capture Therapy

Abstract Extracellular vesicles such as exosomes are expected to be used as drug delivery vehicles, particularly in personalized medicine, due to their pharmacological advantages. However, the development of functionalization techniques for isolated extracellular vesicles—includi...

Strontium isotopic signatures and source apportionment in urban soils of Salgótarján: unraveling the impact of industrial emissions

Abstract Urban soil contamination is primarily associated with human activities, especially industrial by-products, which have introduced high concentrations of heavy metal(loid)s from diverse sources over centuries of city development. This study investigated the distribution of...

Temperature Dependence of Elemental Depth Profiles at the Au/Si Interface Using Confocal Micro X‐Ray Fluorescence Analysis

ABSTRACT This study aims to establish a method for nondestructively evaluating the elemental diffusion behavior at metal/semiconductor interfaces in situ, which is extremely important for reliability assessment of next‐generation semiconductor devices. Confocal micro X‐ray fluore...

Conditions Supporting Autonomous Information and Communication Technology Use Among Community-Dwelling Older Adults: A Qualitative Content Analysis

Information and communication technology (ICT) is increasingly promoted to support health and participation among older adults. However, the conditions under which older adults perceive ICT as usable in their daily lives remain unclear. This qualitative descriptive study explored...

Functional Heterogeneity of Fusobacterium nucleatum Subspecies in the Immune Microenvironment of Oral Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC) develops through multiple pathogenic and environmental factors. Increasing evidence suggests that the oral microbiota, particularly intratumoral bacteria, is also associated with OSCC progression; however, the relationship between individual ba...

Reaction of α-Iodoalkyldifluoroboranes with Copper(II) Carboxylates via a Tetracoordinate Boron Intermediate

Abstract The reaction of α-iodoalkyldifluoroboranes with copper(II) carboxylates affords α-acyloxyalkyldifluoroboranes. In this process, the high Lewis acidity of alkyldifluoroboranes constitutes the driving force for the formation of a tetracoordinate boron intermediate, as sugg...

Smartphone step-count patterns and later QMCOO-defined frailty-related risk

Smartphone steps offer low-burden signals. Their incremental value for later frailty-related risk defined by the Questionnaire for Medical Checkup of Old-Old (QMCOO) remains uncertain. We analyzed users of Osaka’s Asmile app. Step-count features from November–December 2024 were r...