The University of Texas Rio Grande Valley

Effect of features burdened with classical error, misclassifications, Berkson error, and group-summary assignments on machine learning performance and interpretability

Abstract Measurement error is widespread in modern data pipelines, but its influence on predictive modeling and variable importance assessments in machine learning is often underestimated. Our study examines how input measurement error affects both prediction accuracy and interpr...

The circulating lipidome in severe obesity

Severe obesity (SevO; BMI ≥ 40 kg/m 2 ) is rising globally yet remains understudied mechanistically. To characterize lipidomic alterations at the species level, we analyzed Border Health Research Cohort participants with fasting plasma lipidomics and genetic data, comparing SevO...

The silent pandemic: the overlooked toll of stroke compared to COVID-19

The COVID-19 pandemic will be remembered as one of the defining health crises of the modern era. The World Health Organization reported approximately 7 million deaths attributed to COVID-19 globall...

Treating co‐occurring alcohol use disorder and major depressive disorder: A systematic review of combination and multimodal pharmacotherapy

BACKGROUND AND OBJECTIVES: Major depressive disorder (MDD) and alcohol use disorder (AUD) frequently co-occur and are associated with greater symptom severity and elevated suicide risk relative to either disorder alone, yet no pharmacological regimen is approved for the combined...

Diabetes-Induced Organ Damage: Cellular Mechanisms and Therapeutic Opportunities

Diabetes mellitus is a metabolic disorder characterized by insulin resistance and impaired pancreatic beta-cell function, resulting in sustained hyperglycemia [...]

Thermal monitoring of solidification in molded casting of drone landing leg

This paper presents the design, fabrication, and thermal characterization of an acrylonitrile butadiene styrene (ABS) mold produced by fused deposition modeling (FDM) extrusion-based additive manufacturing used for the wax casting of a drone landing leg. A thermal monitoring fram...

Energy market and carbon emission spillovers in critical minerals investment: a dynamic connectedness approach

Purpose This paper aims to examine the daily financial risk spillovers associated with investing in critical minerals. It examines the dynamic interconnectedness between seven critical mineral Exchange-Traded Fund (ETF) portfolios and key economic-wide variables, including the en...

More Than Hurt Feelings: Associations Between Perceived Racial Discrimination and Mental Health, Substance Use, and Victimization Among Racial and Ethnic Minority Adolescents

Abstract Background Although prior research has linked perceived racial discrimination (PRD) to adverse outcomes among adolescents, fewer studies have comprehensively examined its associations with mental health, substance use, and victimization outcomes within a single nationall...

A new bubblegum coral from the Nazca Ridge reveals chitin as the structural scaffold of skeleton-less Paragorgia colonies

Abstract Bubblegum corals ( Paragorgia ; Corallidae) form among the largest branching colonies in deep-sea environments despite lacking an axial skeleton. How these octocorals maintain structural cohesion using only sub-millimeter sclerites has remained unexplained. Here we descr...

Data and code for "Red noise and evolving signals: a complete frequentist approach to supermassive black hole binary searches with pulsar timing arrays"

The accompanying programs provide the workflow for synthetic PTA generation, evolving continuous-gravitational-wave signal injection, the timing-model-projected likelihood, joint signal-and-noise optimization using particle swarm optimization, signal-to-noise ratio calculations,...

The Sunset Before Home

Inspired by her father's photographs of sunsets, a first-generation medical student reflects on the lessons her immigrant parents taught her about hope, sacrifice, and opportunity. What once appeared to be simple family moments became a deeper understanding of gratitude and persp...

In Situ Generation of Biocidal Copper Iodide via Reactive Nanoenergetic Systems

ABSTRACT In situ generation of copper iodide (CuI) was achieved through the ignition of nanoenergetic system designed to release copper and iodine species. Aluminum–copper oxide and aluminum–iodine pentoxide thermite mixtures were combined in proportions ranging from 25 to 75 wt....

Using Approximations of Practice to Support Calculus Instructors’ Enactment of Equitable Active Learning Teaching Practices

Abstract We implemented a semester-long professional development workshop series to help Calculus I and II instructors implement active learning and equitable teaching practices. The workshops actively engaged instructors in approximations of practice (Grossman et al., 2009) in w...

Optimal Order Time Discretizations for Stochastic Semilinear Wave Equations with Multiplicative Noise

This paper focuses on developing and analyzing two novel implicit temporal discretization methods for the stochastic semilinear wave equations with multiplicative noise. The proposed methods are natural extensions of well-known time discrete schemes for deterministic wave equatio...

Early Childhood Services for Transfronterizx Families of Autistic Children: Perspectives From Community Providers

In this qualitative study, we investigated the perspectives of early childhood service (ECS) providers on the facilitators and barriers faced by transfronterizx caregivers of autistic children in the U.S.-Mexico border. We applied thematic analysis to focus groups using the socio...

Beyond Bayh-Dole: Mixed-Funded Research and the Governance of University Commercialization in the United States and the European Union

University research commercialization is no longer well described by the conventional model of patenting and licensing alone. Research outputs now move through a broader set of pathways, including data, software, implicit know-how, collaborative platforms, and long-term research...

Pedagogical Moves for Provoking Prospective Teachers’ Intellectual Needs while Connecting Abstract Algebra and Secondary Mathematics

Researchers have exhibited ways in which prospective secondary mathematics teachers can connect content from abstract algebra with secondary mathematics in ways that reshape their understanding of secondary mathematics and thereby support their teaching of that content. However,...

Discovery of Ro 41‐0960, a Non‐Steroidal Inhibitor of the Na + /K + ‐ATPase

The Na + /K + ‐ATPase (NKA) is a central regulator of cardiac ion homeostasis and a validated target for heart failure. Yet, cardiotonic steroids used in clinical practice are limited by a narrow therapeutic window and pro‐arrhythmic effects. Here, we identify Ro 41‐0960 as a non...

The derived depth formula for modules of finite quasi‐projective dimension

Abstract Let be a commutative Noetherian local ring. We prove a variety of new formulas for modules of finite quasi‐projective or finite quasi‐injective dimension. These include the Derived Depth Formula, itself an extension of Auslander's famous depth formula, a variation of the...

Integration of lipidomic and polygenic risk scores within contemporary clinical cardiovascular risk assessment pathways: a multi-cohort development and validation study

Background Guideline-recommended clinical risk scores such as AusCVDRisk underestimate cardiovascular disease (CVD) risk in a substantial proportion of individuals who later experience events, with up to 65% initially classified as low or intermediate risk. This limitation is mos...