The People's Hospital of Guangxi Zhuang Autonomous Region

Burden of Crohn’s disease in East Asia: a 34-year analysis with projections to 2060

Abstract Purpose Crohn’s disease has transitioned from a rare condition to a significant public health concern in East Asia, yet comparative evidence across countries and long-term projections remain limited. We assess national trends in the burden of Crohn’s disease in China, Ja...

Organising cross-border care after arrival: receiving-system challenges in a China–Vietnam border region

Cross-border healthcare is increasingly visible in border regions where patient mobility develops faster than the institutional arrangements needed to support care. Existing research has often examined why patients seek care abroad, while less is known about how receiving health...

Benzothiazole derivatives target oligoadenylate synthetase and enhance RSV vaccine efficacy as adjuvants

2′,5’ oligoadenylate (2-5A) activates RNase L to degrade intracellular RNA and inhibit viral proliferation. The resulting nucleotide fragments bind RIG-I-like receptors to initiate type I interferon (IFN-I) signaling, enhancing maturation of antigen processing cells to trigger ad...

Adherence to the DASH diet moderates the association between sedentary time and the risk of obstructive sleep apnea in a hypertensive rural Chinese population: a cross-sectional study

Obstructive sleep apnea (OSA) and hypertension form a vicious cycle. While sedentary behavior is an emerging risk factor for OSA, and the dietary approaches to stop hypertension (DASH) diet offers cardiometabolic benefits, their interplay in non-obese hypertensive patients remain...