Texas Children's Hospital

Intra-abdominal Bowel Dilation in Experimental Gastroschisis Is Associated With a Modifiable Transcriptomic Program of Intestinal Dysfunction

OBJECTIVE: To characterize intestinal transcriptional profiles in gastroschisis, their temporal evolution, and response to fetal intervention. SUMMARY BACKGROUND DATA: Gastroschisis causes significant intestinal dysfunction, with intra-abdominal bowel dilation clinically shown to...

Spring Cranioplasty for the Fused Lambdoid and Coronal Sutures: Expanding Indications

Abstract Spring cranioplasty, originally developed for sagittal synostosis, has expanded to address selected lambdoid and coronal deformities by applying continuous mechanical distraction to gradually expand the cranium while avoiding the extensive dissection required for open va...

Cost-benefit analysis of universal pool fencing for Texas households with young children

Abstract Background Texas bears a disproportionate burden of pediatric drowning in the United States. Functional pool fencing prevents pediatric drownings, but its economic impact on drowning-related costs remains unclear. We estimated the potential cost savings of implementing a...

Development and validation of the arabic version of the Spine Functional Index (SFI-AR) in patients with spinal disorders

Background The Spine Functional Index (SFI) is a patient-reported outcome measure used to evaluate functional limitations in patients with spinal disorders. However, no validated Arabic version has been available, limiting standardized assessment in Arabic-speaking populations. M...

Impact of the COVID-19 Pandemic on Viral Respiratory Testing in Children With Abnormal Urinalysis

OBJECTIVE Respiratory viral panels (RVP) are common, expensive tests that often do not change treatment, especially in children with suspected urinary tract infections. In children with abnormal urinalysis (UA) results, we hypothesize that RVP overuse existed before the COVID-19...

Best-Practice Perioperative Optimization for Craniosynostosis Surgery

Abstract Perioperative optimization in craniosynostosis surgery demands coordinated attention across the preoperative, intraoperative, and postoperative periods, yet considerable practice variation persists across craniofacial centers. Surgical approaches range from minimally inv...

A Rare BCR::SPECC1L::ABL1 Fusion in a Pediatric Chronic Myeloid Leukemia Patient

BACKGROUND: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm typically defined by BCR::ABL1 p210 fusions isoforms. OBSERVATIONS: An 8-year-old female CML patient harbored a typical t(9;22)(q34;11) Philadelphia chromosome and BCR::ABL1 fusion by conventional karyoty...

Injury Severity and Near-Absent Helmet Use in NTDB-Eligible Pediatric E-Scooter Trauma: A Single-Center Descriptive Series

Pediatric e-scooter injuries have risen rapidly, yet single-center data describing injury severity, admission patterns, and helmet use within high-acuity trauma populations remain limited. We describe a single-center retrospective series of 31 National Trauma Data Bank (NTDB)–eli...

Management of Infantile Epileptic Spasms Syndrome: A survey of US pediatric hospitals

Abstract Objective To evaluate the management practices of Infantile Epileptic Spasms Syndrome (IESS) across tertiary pediatric hospitals in the United States using a survey‐based approach. Methods A 21‐question survey focused on management setting, work‐up, follow‐up and treatme...

The Impact of Earthquake-Induced Healthcare Disruption on an Established Developmental Hip Dysplasia Screening Program in an Earthquake Zone

Background/Objectives: Pandemics and natural disasters may delay the diagnosis and treatment of developmental dysplasia of the hip (DDH). In this study, we evaluated the effect of 2023 Kahramanmaraş earthquake-induced healthcare disruption on the DDH screening program. Methods: M...

Disparities in Hospital Length of Stay and Morbidity in Acute Care Pediatric Cardiology Patients

BACKGROUND Multicenter collaborative studies examining disparities in in-hospital outcomes are lacking in pediatric cardiology. We hypothesized that Black and Hispanic patients in pediatric acute care cardiology units (ACCUs) have increased length of stay (LOS) and complications...