Texas A&M University

Curve fitting algorithm for multimodal particle size distributions – a theoretical basis

Abstract. Here we detail an open-source curve fitting algorithm for multimodal particle size distributions (MPSDs) and evaluate it against a ten-year dataset of ambient particle size distribution (PSD) measurements collected at Storm Peak Laboratory, a remote mountainous research...

Restoration of oscillatory shear stress in humans activates an endothelial protective genetic program and prevents DVT

Deep vein thrombosis (DVT) is a major cause of morbidity and mortality in critically ill patients. DVT clots typically form in the sinus of the deep venous valves and are strongly associated with immobility and reduced venous flow. Physical activity alters venous blood flow, gene...

“Nobody Wants to Die That Way”: The Intersection of Immigration Enforcement and Emergency Medical Services in a Rural South Texas County

Abstract The purpose of this study was to explore the influence of migration and immigration enforcement on this inland, rural community’s EMS clinicians and first responders. We conducted 13 in-depth interviews with emergency responders in a rural county in Texas. Interviews wer...

Dissociable Roles of Primary Motor and Supplementary Motor Cortex in Shaping the Neural Drive to Muscle

Abstract The primary motor cortex (M1) and supplementary motor area (SMA) are critical for motor execution and planning, yet their distinct causal contributions to modulating the neural drive to muscles remain incompletely understood. To dissociate their roles, we applied inhibit...

The impact of work from home on urban expansion: a GIS simulation via an intelligent self-adapting multiscale agent-based model

Urban land use is increasingly shaped by evolving work modalities, particularly the rise of Work from Home (WFH) arrangements. This study introduces a hybrid Artificial Neural Network – Agent-Based Modeling (ANN – ABM) framework to simulate urban expansion under differentiated wo...

Perceptions of turnout gear fit and movement restrictions among firefighters of different gender, service type, and measurement status

To understand the factors contributing to ill-fitting gear, this study investigated user perceptions across firefighters of different gender, service type, and pre-sizing measurement status. A total of 345 firefighters (19.8% women, 34.8% volunteer firefighters, and 18.0% not mea...

Gemfibrozil promotes longevity and health by restricting amino acid uptake through the Dipeptide transporter, PEPT1

The FDA-approved fibrate, gemfibrozil, has been used clinically to treat hyperlipidaemia, showing efficacy both in lowering triglycerides and increasing high-density lipoproteins. However, in recent years, the drug has been increasingly investigated for potential clinical use in...

Effects of excipient particle size range on the performance of selective laser sintered pharmaceutical printlets

This study investigates how the particle size range (PSR) of the polymeric component in a powder mixture affects the structural strength and drug release rate of additively manufactured pharmaceutical tablets (printlets). These printlets were fabricated via Selective Laser Sinter...

Serotonin Transporterand Organic Cation Transporter3 Contribute to Basolateral Amygdala Serotonin Clearance and RecentFear Memory Recall

Abstract Converging evidence implicates dysregulation of serotonin in emotion-related psychiatric disorders. Leading pharmacotherapies for such disorders, including general anxiety and posttraumatic stress disorders, target the serotonin transporter (SERT); yet, selective seroton...

Influence of pore fluid viscosity and fluid-clay interactions on the hydromechanical response of resedimented kaolinite

Abstract Understanding how pore fluid properties influence the hydromechanical behavior of clay-rich formations is essential for evaluating the performance and long-term stability of subsurface geoenergy systems, including caprock integrity, storage containment, and unconventiona...

Direct avirulence effector-receptor interaction confers wheat immunity against insects

Wheat immunity against the global pest Hessian fly operates on a gene-for-gene basis, yet molecular mechanisms underlying resistance-avirulence interactions have remained elusive for over five decades due to the absence of any cloned insect-resistance gene. Here, we cloned the H1...

Examining smartphone-assessed executive function metrics and intrinsic resting-state functional connectivity in depression

<title>Abstract</title> Major Depressive Disorder (MDD) is a common and costly mental health condition that is often associated with deficits in executive function. Smartphone applications (“apps”) have emerged as promising methods for assessing mental health-related outcomes in...

Delivering building demand flexibility for grid-interactive operation: from perception and cognition to decision, execution, and verification

As both buildings and power systems undergo rapid decarbonization, demand flexibility (DF) in buildings has emerged as a key enabler for renewable energy integration, grid reliability, energy resilience, and efficient and low carbon operation. By dynamically adjusting building en...

An orbifold framework for classifying layer groups with an application to knitted fabrics

Abstract Entangled structures, such as textiles and architected materials, are often doubly periodic. Owing to this property and their finite transverse thickness, the symmetries of these materials are described by the crystallographic layer groups. While orbifold notation provid...

Structure-based TCR-pMHC binding prediction and generalization to unseen peptides

Abstract The interaction between T-cell receptors (TCRs) with the peptide-bound major histocompatibility complex (MHC) intricately impacts the functional specificity of T-cell-mediated adaptive immune response. Consequently, implication in immunotherapy has contributed to the eve...

Clustered coloring of graphs excluding a subgraph and a minor

A graph coloring has bounded clustering if each monochromatic component has bounded size. Equivalently, it is a partition of the vertices into induced subgraphs with bounded size components. This paper studies clustered colorings of graphs, where the number of colors depends on a...

Symmetrization maps and minimal border rank Comon’s conjecture

Abstract One of the fundamental open problems in the field of tensors is the border Comon’s conjecture : given a symmetric tensor $$F\in (\mathbb {C}^n)^{\otimes d}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mi>F</mml:mi> <mml:mo>∈</mml:mo> <mml:m...

Tracking the baryon number with nuclear collisions

Baryon quantum number is found to be conserved since baryogenesis in the early Universe. Conventionally, each fractionally charged valence quark is understood to carry one-third of a baryon number. An alternative hypothesis posits that baryon number is instead carried by a baryon...

Primary Care Clinical Rotations Are Associated with Shifts in Senior Veterinary Students’ Perceptions of Scope, Complexity, and Career Alignment

The study objective was to evaluate changes in senior veterinary students' perceptions of companion animal primary care and career preferences following a primary care clinical rotation. A multi-institutional survey was administered to veterinary students at 10 US colleges of vet...

Polymeric Sorbents as Energy‐Efficient Alternative to Cryogenic Distillation for Light Hydrocarbon Purification

Light hydrocarbons are essential gaseous compounds for fuel, polymer manufacturing, fertilizer production, and so forth. The efficient recovery and purification of these gases are still challenging despite their significant industrial and domestic relevance. They exist in the gas...