Stockholm University

RNA degradation by DIS3 is a necessary step in the resolution of backtracked transcription complexes

Summary The RNA exosome is known to participate in transcription, but the contribution of its ribonuclease activities to this process remains unclear. Here we investigated the role of DIS3, one of the exosome ribonucleases, in transcription by RNA polymerase II (RNAPII). Rapid de...

Socio-hydrogeology: The past, present, and future of a people-centred and place-based approach to groundwater science

Groundwater systems are shaped by deeply interwoven physical processes and social dynamics, yet traditional hydrogeological approaches have often treated these domains separately. Over the past decade, socio-hydrogeology has emerged in response, offering an approach that systemat...

Grounding-line dynamics in a Stokes ice-flow model (Elmer/Ice v9.0): improved numerical stability allows larger time steps

Abstract. The efficient and accurate simulation of grounding line dynamics in marine ice-sheet models remains a challenge, largely due to restrictive time-step limitations. The restrictive time step size of ice-sheet simulations (∼ ∆t = 0.01−0.5 years) has led to the routine use...

A compilation of global bio-optical in situ data for ocean-colour satellite applications – version four

Abstract. A global in situ dataset for validation of satellite products from the ESA Ocean Colour Climate Change Initiative (OC-CCI) is presented. This version of the compilation, with data starting in 1996, extends to 2025, which is important for the validation of recent algorit...

Fitness effects of local seasonal adaptation depend on the timing of reproduction in a range-expanding butterfly

Abstract Local seasonal adaptation across latitudes is ubiquitous, but its fitness consequences are rarely estimated in the field. Using a common-garden field experiment at the northern range margin of the butterfly Lasiommata megera, we show that fitness consequences of among-po...

The COVID-19 pandemic’s impact on psychotropic medication prescriptions for children and adolescents: a scoping review of quantitative longitudinal studies

Abstract Global evidence shows a deterioration in the mental health of children and adolescents during the COVID-19 pandemic, raising questions about how mental health care, including psychotropic medication prescriptions, has adapted. However, it remains unclear how this deterio...

Forecast-based attribution of the role of stratospheric variability in weather extremes

Abstract. Variability of the stratospheric polar vortex, particularly its dramatic breakdown during sudden stratospheric warming (SSW) events, has been linked to a number of surface weather extremes. However, attributing the role of stratospheric variability in a specific observe...

Enzymatic degradation of conjugated polymer thin films for electrochemical transistors

Degradable imine linkers within the polymer backbone enabled acid-triggered organic mixed ionic–electronic conductors (OMIECs). Yet, for many bioelectronic applications, OMIECs must work in direct contact with physiological fluids, making it challenging to achieve both excellent...

Critical Pedagogy of Multicultural Incorporation

Abstract This article brings cultural sociology, civil sphere theory, and critical theory into dialogue to examine the empirical-cum-political stakes of education in multicultural societies. Using a mixed-methods approach, it analyzes school cultures in Finland, Scotland, and Swe...

Availability and representativeness of freshwater macroinvertebrate data to enable Europe-wide assessment of biodiversity trends

Freshwater ecosystems, though covering less than 1% of Earth's surface, harbor around 10% of all species. Pressures like pollution, water extraction, and habitat loss can exhibit complex interactions in their effects on freshwater biodiversity. Understanding the effects of these...

Spatial structure and growth dynamics of fairy rings formed by Marasmius oreades

Abstract Despite the long-term fascination of fairy ring-forming fungi, many aspects of their biology remain unresolved. It is not known why the mycelium grows as an annular structure, rather than a solid disc, or why it grows radially outwards. Different theories have been sugge...

Sleep disturbances as early indicators of incident psychiatric disease

PURPOSE: Sleep disturbances are common in individuals with psychiatric diseases and may emerge years before diagnosis. It remains unclear whether they reflect modifiable risk factors or early manifestations of psychiatric illness. We aimed to investigate how different sleep dimen...

Quaternary Arctic planktonic foraminifera: morphological differentiation and taxonomic reassessment of subpolar spinose taxa

Abstract. Planktonic foraminifera in the modern Arctic Ocean are dominated by the non-spinose polar species Neogloboquadrina pachyderma. Acmes of two spinose, presumed subpolar taxa in Quaternary central Arctic sediment cores are therefore anomalous, implying significantly differ...

Problem gambling and affected others: health, relational and economic outcomes across longitudinal trajectories in a population-based Swedish study

Abstract Background Exposure to another person’s gambling problems has been linked to a range of adverse outcomes among affected others (AOs); however, most evidence is based on cross-sectional studies. Less is known about how such outcomes vary over time and across different pat...

Use of machine learning to enhance detection of transient astronomical phenomena in historical observatory images

Transient, star-like point sources that appear and vanish over short timescales are described in astronomical images prior to launch of Sputnik. We have reported that transient numbers diminish significantly in Earth’s shadow (shadow deficit) and are more likely within (+/-) one...

Balancing forage and fear: How people, environment and predators shape reindeer grazing in the Fennoscandian tundra

Abstract The long history of reindeer herding in Fennoscandia has shaped the mountain tundra by influencing its productivity, nutrient and carbon cycling and vegetation structure. By partly limiting shrub expansion, extensive reindeer grazing contributes to ecosystem resilience a...

DECODING THE FOURFOLD VOYNICH CIPHER - Voynich Folio 57v

Folio 57v (f57v) of the Voynich Manuscript (MS 408) has long been recognized as a critical diagnostic hub due to its prominent circular diagrams and unique repeating text strings. Historically, the absence of extensive repetitions across the entire codex has frustrated standard c...

The Fertility Reduction Effects of the Colorado Family Planning Initiative by Age and Parity

ABSTRACT We use restricted‐access birth records from the National Vital Statistics System (NVSS) to document the full age and parity fertility effects of the Colorado Family Planning Initiative (CFPI). The CFPI provided access to every FDA approved method of contraception for fre...

Sibling group sex composition and gender-typical educational choices

Educational choices are heavily stratified by gender. In this study we examine whether an important structural factor in the family of origin, sex composition of the sibling group, affects the emergence of the gender-typed preferences that may drive these choices. Using Swedish p...

Exposure to workplace bullying and violence/threats of violence and subsequent working life expectancy among older workers: A Swedish prospective cohort study

OBJECTIVES: This study aimed to quantify possible associations between exposure to workplace bullying and violence, or threats thereof, and working life expectancy (WLE) among older workers in Sweden. METHODS: We conducted a prospective cohort study using data on 12 920 individua...