State Scientific Center of the Russian Federation - Federal Medical Biophysical Center named after A.I. Burnazyan

Synthesis, Cytotoxicity and Antimicrobial Action of 11 Analogs of Nifuroxazide

The global spread of multidrug-resistant bacteria, alongside the rising burden of oncological diseases, poses an increasing threat to human health and public healthcare systems worldwide. Substantial efforts are underway to discover new drugs and to reposition or repurpose existi...

Modern approaches to the treatment of NCMT sexually transmitted infections (N. gonorrhoeae, C. trachomatis, M. genitalium, T. vaginalis). Part II. M. Genitalium

An analysis of literature data on modern approaches to the treatment of infection caused by M. Genitalium is presented. As for now, it is not included in the list of reportable infections both in most countries of the world and in the Russian Federation, but, according to various...

Glaucoma and age-related macular degeneration: challenges and prospects for prevention and treatment of combined pathology. Part 1. Epidemiology and pathogenesis

Glaucoma and age-related macular degeneration are the leading causes of irreversible vision loss in individuals over 60 years of age. This review consolidates current data on the epidemiology, shared genetic factors, and pathophysiological mechanisms underpinning their coexistenc...

Laser-Generated Ultrashort Pulsed Electron Beams Induce p53-Related Alteration of DNA Repair and Cell Death Pathways in Non-Small Cell Lung Cancer Cells

Laser-driven accelerated particle beams have significantly advanced cancer treatment by facilitating the delivery of exceptionally high dose rates of radiation to solid tumors within femto- to picosecond timescales. This investigation compared the radiobiological effectiveness of...