State Key Laboratory of Microbial Technology

Brassinosteroids improve nitrogen utilization by antagonizing BIN2-mediated SnRK1 activation

Nitrogen is an essential nutrient for plant growth and development, and is central to increasing crop yield. Brassinosteroids (BRs) and their analogs are widely used in agriculture to enhance crop yields and improve nitrogen utilization, yet the underlying mechanism remains fragm...

Microfluidic-based high-throughput isolation enhances the recovery of novel strains and diversity from Arctic soil microbiome

ABSTRACT Microbial cultivation remains essential for understanding the physiology, ecology, and biotechnological potential of environmental microbes, yet conventional plate-based methods (CPM) recover only a minute fraction of the environmental microbiome. Polar regions, particul...

Additive-Assisted Consolidated Bioprocessing of Untreated Desert Willow (Salix psammophila) for Bioethanol Production by a Thermophilic Co-Culture

Consolidated bioprocessing (CBP) using Acetivibrio thermocellus offers a promising route for the direct conversion of recalcitrant lignocellulose into ethanol. In this study, a synergistic co-culture system comprising A. thermocellus C1 and Thermoanaerobacterium thermosaccharolyt...

ExMODE: A comprehensive resource for extremophile genomic and functional exploration

ExMODE (https://db.genomics.cn/exmode/) integrates 3518 samples to build a unified extremophile resource, which hosts 1.35 billion habitat-specific non-redundant genes, 5.25 million representative protein structures, 67,026 metagenome-assembled genomes (MAGs), and 164,132 biosynt...

Mechanistic Insights into the Anti-Inflammatory Activity of a Sulfated α-Glucan (VpG) from Volutharpa ampullacea perryi

A novel sulfated α-glucan (VpG), with an ultra-high molecular weight of approximately 2250 kDa and a sulfation degree of 18.6%, was previously isolated from Volutharpa ampullacea perryi and shown to alleviate dextran sulfate sodium (DSS)-induced ulcerative colitis in mice. Howeve...

TaIAA25 negatively regulates wheat alkaline tolerance by inhibiting plasma membrane H + -ATPase activity

Soil salinization/alkalization represents a universal challenge that severely constrains crop productivity. Elucidating the molecular mechanisms underpinning saline/alkaline tolerance of wheat ( Triticum aestivum ) holds profound significance for global food security and sustaina...

Morphological and Size‐Dependent Enrichment of Endotoxins in Coastal Spray Aerosols: Implications for Regional Respiratory Health Risks

Abstract Sea spray aerosols (SSA) transport bioactive substances that affect the Earth's environmental and climate system. We investigated the enrichment of endotoxins (LPS), characterized their influence on the SSA morphologies, and evaluated the respiratory tract deposition. LP...

Antarctic Circumpolar Current creates a boundary limiting the meridional dispersal of bacteria in the Southern Ocean

Impact statement As the world's largest ocean current in terms of volume transport, the Antarctic Circumpolar Current (ACC) significantly affects the movement of heat and water in the Southern Ocean. However, the impact of the ACC on the biogeographic distribution of marine bacte...