SRM Institute of Science and Technology

Mechanistic integration of genetic alterations, PTM signaling, and tumor microenvironment remodeling in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies, with late diagnosis, rapid progression, considerable therapy resistance, and low overall survival. Growing evidence suggests that PDAC progression is not determined by simple genetic events but rather d...

Effect of nanoclay and seashell filler addition on physical, mechanical, thermal and flammability characteristics of natural fiber hybrid polymer composites

In the current work, physical, mechanical, and flammability characteristics of Sida acuta (SA)/ Abutilon indicum (AI) natural fiber reinforced hybrid composites added with two fillers nanoclay at 1, 1.5, 2 and 3.0 wt% and with seashell powder at 5, 10 and 15 wt% was investigated....

Precursor Concentration-Induced Modulation of Structural and Surface Properties of Cobalt Ferrite for Enhanced Phenol Photodegradation Under UV–Vis Irradiation

Cobalt ferrite (CoFe2O4) photocatalysts were synthesized through a citric acid–ethylene glycol-assisted sol–gel route by systematically varying the Co2+ precursor concentration from 0.1 to 0.5 M. Precursor concentration significantly influenced the structural, optical, surface, a...

Dose dependent nano bio interactions of green synthesized Achyranthes aspera capped CuO nanoparticles

Understanding concentration-dependent nano bio interactions is essential for developing safe and biologically functional nanomaterials. In this study, copper oxide nanoparticles (CuO NPs) were green-synthesized using Achyranthes aspera leaf extract and evaluated for their physico...

Intelligent adaptive energy management framework for hybrid solar-grid EV fast-charging stations with energy storage and time-based demand response optimization

The rapid expansion of electric vehicle (EVs) is significantly increasing pressure on the conventional electrical grid and introducing new challenges in load management, peak demand, and grid stability. Conventional grid systems, dependent on fossil fuel-based generation, contrib...

Harnessing polymeric materials for applications in electric vehicle with sustainability contributions and prospects

The accelerated global shift to EVs is revolutionizing the field of materials science, thereby making polymeric materials indispensable to all subsystems in EVs. In this context, this review provides a critical analysis of the evolution, classification, and applications of polyme...

Assessment of parental knowledge on childhood developmental milestones and associated factors among parents of children under 5 years in Addis Ababa, Ethiopia

Parents’ knowledge of developmental milestones helps promote healthy development and appropriate expectations. Limited knowledge may contribute to neglect, abuse, and delayed recognition of developmental problems. Despite efforts to prevent developmental delays in Ethiopia, evide...

Beyond the Needle: Transforming Traditional Healthcare with Microneedle Drug Delivery Systems

In the present era, modern drug delivery systems play a fundamental role in ensuring the systematic delivery of the drug into the body, reaching the desired targets. Across recent decades, the drug delivery system has evolved from simple oral and injectable formulations to interp...

Tumescent Versus Non-Tumescent Technique in Split-Thickness Skin-Graft Harvesting: A Systematic Review and Meta-Analysis

OBJECTIVE: Taking a split-thickness skin graft (STSG) is a common reconstructive procedure, but the donor site often causes patients significant pain and bleeding. The authors investigated whether the tumescent technique is a better, safer method for harvesting these grafts. DATA...

Distribution and Clustering of Beta-Thalassemia- and Sickle Cell-Related Disorders Among Scheduled Tribes in Tamil Nadu: An Exploratory Multivariate Analysis

Background/Objectives: Beta-thalassemia and sickle cell disorders are among the most common inherited hemoglobin disorders affecting tribal populations in India, with marked ethnic and geographic heterogeneity. Although exploratory multivariate approaches have been used, only lim...

Homocysteine, vitamin B6, vitamin B12 and folate profiles in acute ischemic stroke: a hospital-based case-control study

Homocysteine and its vitamin cofactors are associated with vascular biology, but post-stroke measurements are vulnerable to confounding and reverse causation. This study compared serum homocysteine, vitamin B6, vitamin B12 and folate between adults with acute ischemic stroke and...

3D bioprinting in dermatological therapeutics: Technologies, applications, and clinical perspectives

With the emergence of 3D bioprinting, the biofabrication of artificial skin has become possible through the precise arrangement of cells that can imitate the complexities of the skin tissue structure and functions. The current paper reviews concepts on skin drug delivery, paying...

A compact and component-optimized 13-level switched-capacitor multilevel inverter with high efficiency

Switched-Capacitor Multilevel Inverters (SCMLIs) provide a viable pathway to achieving high-quality voltage synthesis with reduced reliance on magnetic components; however, existing 13-level implementations typically require a high number of switching devices and exhibit elevated...

Wideband dielectric resonator antenna for K-Band/n258 applications with intelligent response filtering

This work presents a wideband rectangular dielectric resonator antenna (RDRA) integrated with a machine learning (ML) response filtering framework for K-band and 5 G NR n258 applications. The antenna utilizes an RT/Duroid 5880 substrate, a partial ground plane, a heart-shaped str...

Clinical efficacy of ezetimibe add-on to atorvastatin on lipid profile in post-PCI patients: evidence from a south indian population

Cardiovascular diseases often cause severe ischemic block or narrowing of coronary arteries, obstructing blood flow to the myocardium. Percutaneous coronary intervention (PCI) is a nonsurgical, invasive procedure for treating these conditions. Statins are the standard secondary p...

Performance studies of a conical solar distiller using peanut shell‐integrated phase change materials: Energy and exergy analysis

Abstract This manuscript discusses the effect of peanut shells, peanut shells packed with PCM, on the performance of the conical solar distiller (CSD). Three CSDs, namely CSD containing peanut shells filled with PCM (CSD‐PS&PCM), CSD containing peanut shells (CSD‐PS), and traditi...

Mode division multiplexing using Laguerre–Gaussian beams with VSB-CSRZ modulation for high-capacity underwater optical wireless communication

Abstract Underwater optical wireless communication (UOWC) is a promising technology for high-speed data transmission underwater due to its large bandwidth, low latency, and high capacity. In this work, a high-capacity UOWC system based on mode division multiplexing (MDM) and vest...

Recent progress in engineering molybdenum diselenide based electrocatalysts for hydrogen evolution reaction in acidic medium

Hydrogen production through electrochemical water splitting has attracted substantial interest as a low-carbon route for future clean energy systems. However, the widespread adoption of this technology is largely constrained by the dependence on noble-metal catalysts for the hydr...

Personalized risk assessment of musculoskeletal disorders using artificial intelligence enabled predictive imaging models

Abstract Musculoskeletal disorders (MSDs) impose a substantial burden on mobility, quality of life, and healthcare systems, while early individualized risk stratification remains difficult because structural, clinical, and biomechanical determinants interact nonlinearly. This stu...

Deciphering rGO-Driven Interfacial Modulation: Bridging Frequency−Voltage-Dependent Electrical Characteristics and Electrochemical Performance in NiO/ZnO Composites

Abstract The rising energy demand and exhaustion of fossil fuel resources have expedited the search for efficient and sustainable energy storage technologies. This study presents the hydrothermal synthesis of NiO/ZnO (NZ) binary nanocomposite and its ternary nanocomposites with 4...