Southwest Jiaotong University

Self-Reinforcing Nanozyme-Integrated Microneedles Orchestrate Cascaded Regulation of ROS Homeostasis for Infected Wound Healing

Abstract Chronic diabetic wounds represent a severe complication of diabetes mellitus and a prototypical form of chronic nonhealing wounds, characterized by biofilm-associated infection, persistent inflammation, and impaired angiogenesis. Herein, a multifunctional microneedle pla...

Holding All the Cards from the Good Old Days: How Nostalgic Cues Enhance Artificial Intelligence Service Acceptance

Although artificial intelligence (AI) has become deeply integrated into services, many customers exhibit low acceptance of AI-driven offerings. Identifying effective and efficient ways to enhance AI acceptance is both theoretically significant and practically valuable. Drawing on...

Seasonally Adaptive Natural Ventilation for Sustainable and Energy-Efficient Large-Space Railway Stations in Hot-Summer and Cold-Winter Regions: A Case Study of Chengdu Station

The rapid expansion of high-speed railway networks has increased the operational energy demand and indoor overheating risk of large-scale, high-volume railway station buildings. Natural ventilation is a climate-responsive passive strategy that can improve indoor environmental qua...

Beyond cholesterol: targeting ceramide signaling in cardiorenal metabolic crosstalk

Cardiovascular-Kidney-Metabolic (CKM) syndrome is associated with increased risks of cardiovascular mortality and target organ failure. Despite optimal lipid-lowering therapies, patients remain at substantial residual risk for adverse cardio-renal outcomes. Conventional cholester...

Dual-path domain adaptation network for cross-speed brake pads state monitoring in high-speed trains under long ramps

High-speed trains require prolonged continuous braking to control speed under long ramps, causing brake pads to suffer from uneven wear, exfoliation, and crack damage due to sustained heavy loads. However, the rotational speed varies continuously during braking under long ramps,...

Effects of Lanthanum Doping on Structural Evolution, Morphological Features, and Flux Pinning in FeSe0.5Te0.5 Single Crystals with Machine Learning Assistance

Abstract Single crystals of La x Fe 1− x Se 0.5 Te 0.5 ( x = 0, 0.02, 0.04, 0.06, 0.08) were grown using the self-flux method. A systematic investigation of the effects of La addition revealed changes in the lattice parameters, with the lattice parameter a decreasing and the latt...

Topographic aspect shapes temperature lapse rates and land–atmosphere energy exchange in global mountains

Mountain regions exhibit complex thermal gradients that regulate land–atmosphere energy exchange, yet the global influence of topographic aspect on temperature lapse rates (LRT) remains poorly characterized. Here, we investigate global LRT patterns and their sensitivity to topogr...

Fabrication of Poly(vinylidene fluoride) Ultrafiltration Membranes Using Greener PolarClean and NIDES: Structure Regulation, Performance Enhancement, and Life Cycle Assessment

Abstract Replacing toxic solvents and petrochemical additives in poly(vinylidene fluoride) (PVDF) ultrafiltration (UF) membrane fabrication is essential for advancing sustainable membrane manufacturing. Herein, a greener fabrication route for PVDF UF membranes was developed by em...

Prototype-Driven Semantic Tree with Bimodal Embedding Space for Zero-Shot SAR Ship Recognition

Zero-shot SAR ship recognition aims to identify unseen ship categories without annotated SAR samples, offering a promising solution for open-category maritime remote sensing. Although synthetic aperture radar (SAR) provides all-weather and day-and-night observation capability, pr...

Multidimensional Fragility Analysis of Earth Slopes under Pulse-Like Ground Motions

Abstract Near-fault pulse-like ground motions (GMs), characterized by large-amplitude coherent velocity pulses, have been demonstrated to exhibit a stronger correlation with landslide occurrence than ordinary non-pulse-like GMs. Therefore, comprehensive research on seismic slope...

A Phyllostachys Edulis -Derived Microporous Carbon-Coated Separator with Improved Li+ Transport for Long Cycling Lithium–Chalcogenide Batteries

Abstract Lithium–chalcogenide batteries (LCBs) offer high theoretical energy density but suffer from the polysulfide/polyselenide shuttling during charging and discharging processes with conventional polypropylene (PP) separators, causing low active-material utilization and sever...

Pseudocapacitive Charge‐Driven Adhesive‐Electrocoupling Hydrogels for Myocardial Infarction Repair via Interstitial Microenvironment Remodeling

ABSTRACT Myocardial infarction (MI) creates a hostile microenvironment characterized by oxidative stress, inflammation, fibrosis, and electrical conduction block, posing a multifaceted challenge for tissue repair. To address this, we developed a multifunctional hydrogel (Gel‐PDZC...

Joint scheduling of distributed mixed-line high-speed train bogie maintenance: a multi-agent hierarchical deep reinforcement learning approach

Distributed mixed-line reassembly has emerged as a vital paradigm for high-speed train bogie maintenance. However, spatio-temporal heterogeneity complicates the joint scheduling of line assignments, operations and heavy component transportation. Because reassembly and transport c...

Optimisation design of rail profiles for improving wear and RCF performances on a small-radius curve: A case study

Abstract Wear and rolling contact fatigue (RCF) are regarded as two prominent factors that deteriorate the long-term service performances and aggravate the maintenance costs of metro rails on the small-radius curves, therefore an effective countermeasure against which is needed....

Macrophage-to-myofibroblast transition-derived itaconate promotes bone metastasis in lung cancer through targeting of HSPA8

Abstract Lung cancer bone metastasis carries a poor prognosis, yet the metabolic determinants driving tumour–stroma crosstalk remain largely elusive. Despite extensive investigations into itaconate, a prominent immunometabolite implicated in macrophage polarization, the precise m...

Quantitative Morphological Analysis and Indicator Identification in Linear Market Towns of the Chengdu Plain of Western Sichuan

The traditional market towns of the Western Sichuan Plain, known as Changzhen, represent a distinctive form of vernacular settlement shaped by the interplay of geographical conditions, migration history, and socio-economic dynamics. In the context of rural revitalisation and inte...

Multiscale Mechanisms Governing the Performance Evolution of MgO-GGBS-Stone Powder Lightweight Foamed Soil Under CO2 Curing

To facilitate low-carbon construction technologies in subgrade engineering, this study proposes a carbon-sequestering lightweight foamed soil (C-LFS) using an all-solid-waste binder system in which reactive magnesium oxide (MgO), ground granulated blast-furnace slag (GGBS), and s...

A Comparison Study on the Dynamic Response of Rectangular and Circular Pile–Slab Retaining Walls Against Rockfall Impact

Abstract Pile–slab retaining wall (PSRW), as an innovative passive protection structure for mitigating rockfalls, has been extensively utilized in the western mountainous regions of China. A typical PSRW is composed of reinforced concrete piles, concrete slabs, and a soil cushion...

Engineering design of cobalt-based biomaterials for advanced cancer theranostics: Multimodal synergy, scalable fabrication, and clinical translation

Despite established modalities such as chemotherapy and radiotherapy, cancer treatment remains hindered by off-target toxicity, drug resistance, and adverse effects. Cobalt-Based Biomaterials (Co-BMs) have emerged as versatile nanoplatforms for tumor theranostics, leveraging reve...