Southeast University

PTTG1 drives intestinal-type gastric cancer progression via G2/M checkpoint-mediated cell-cycle reprogramming

Intestinal-type gastric cancer (IGC) progresses through the Correa cascade, yet the molecular determinants of this transition remain insufficiently defined. Using single-cell RNA sequencing (scRNA-seq) on matched normal, intestinal metaplasia, and tumor tissues from five patients...

Does the national sustainable development plan for resource-based cities promote inclusive green growth in both “quantity” and “quality”?

Purpose In China, resource-based cities, being of vital significance for energy and resources, are confronted with severe threats such as depletion, environmental deterioration, and economic disequilibrium. Inclusive green growth, in response to the two predominant global trends...

Manipulating Crystallization and Deprotonation Reaction through Surface Engineering of ZnO for Bright and Stable Near-Infrared Perovskite LEDs

Abstract Perovskite light-emitting diodes (LEDs) have attracted significant attention owing to their rapidly increasing external quantum efficiencies (EQEs). However, achieving bright and operationally stable perovskite LEDs remains a great challenge. Here, we reveal that the mos...

Consonant Articulating Errors in Khmer-Speaking Preschool Children: A Picture-Naming Task Analysis

PURPOSE: Consonant errors (mainly phonetic and phonological errors) as a phenomenon in speech development are frequently observed in preschool children's daily speech communication across languages. Since the Khmer language is a low-source language, consonant articulating error p...

Active flow control strategy for aerodynamic interference reduction in twin-deck bridges: Upstream-deck wake manipulation via the goose optimization algorithm

Aerodynamic interference induced by the construction of a new bridge adjacent to an existing one may adversely affect the aerodynamic performance of the existing structure. To avoid retrofitting the existing structure and traffic control, this study proposes a flow control strate...

AMR-ESVT: Efficient and Accuracy-Preserving Construction of Lightweight Effective Sound Velocity Tables via Adaptive Mesh Refinement

Accurate compensation for acoustic ranging errors is essential for high-precision underwater positioning. However, existing effective sound velocity table (ESVT) methods remain constrained by the computational overhead of dense spatial grids and interpolation smoothing across loc...

Experimental and numerical studies on the fire resistance of reactive powder concrete-filled steel tubular columns

Reactive powder concrete-filled steel tubular (RPCFST) column is composed of high strength reactive powder concrete (RPC) wrapped by outer steel tube. At present, the failure mechanism, stress variation law, decisive factors of fire resistance limit and its calculation method of...

DDOR: Delta Debugging for Explainable Overrefusal Testing and Repair

While safety alignment and guardrails help large language models (LLMs) avoid harmful outputs, they can also induce overrefusal, i.e., unwarranted rejection of benign queries that merely appear risky. We present DDOR (Delta Debugging for OverRefusal), a fully automated and explai...

Optimal estimators and tests for reciprocal effects

The $p_1$ model plays a fundamental role in modeling directed networks, where the reciprocal effect parameter $ρ$ is of special interest in practice. However, due to nonlinear factors in this model, how to estimate $ρ$ efficiently is a long-standing open problem. We tackle the pr...

Triplet Exciton Convergence toward Charge-Transfer States Enables Long-Wavelength Room-Temperature Phosphorescence from Carbon Dots

Abstract Long-wavelength room-temperature phosphorescent carbon dots (CDs), especially the red phosphorescent ones, have garnered significant attention due to their low-energy emission and potential applications. However, the achievement of red phosphorescence in CDs presents a s...

Locally differentially private graph clustering via structure-preserving graph compression

Abstract Locally differentially private clustering is an effective approach to uncover latent structures in decentralized social graphs while preserving individual privacy. Existing solutions encode graph data using adjacency bit vectors, whose high dimensionality introduces subs...

Deep Transformation Model

The increasing data complexity leads to the demand for more general and flexible modeling approaches. We consider a nonparametric transformation model with weak assumptions, which encompasses many popular models as special cases. A rank-based deep neural network (DNN) estimation...

Self-assembled products from natural active compounds: mechanisms and applications in cancer therapy

Natural active compounds (NACs) possess diverse anticancer activities but are often limited by poor aqueous solubility, low bioavailability, insufficient tumor selectivity, and inadequate in vivo stability. Self-assembled products from natural active compounds (SAPNACs) provide a...

A physics-guided generative framework for parameter-conditioned seismic damage visualization of bridge piers

ABSTRACT Traditional seismic damage assessment of reinforced concrete (RC) bridge piers relies on costly finite element (FE) simulations and subjective manual inspections. This study proposes a physics-guided conditional generative adversarial network (PG-CGAN) for continuous and...

Hepatobiliary phase imaging in HCC: revisiting diagnostic algorithms and clinical utility of gadoxetic acid-enhanced MRI across international guidelines

Abstract Hepatocellular carcinoma (HCC) remains a major cause of cancer-related mortality worldwide. In at-risk populations, noninvasive imaging diagnosis relies primarily on the vascular hallmarks of arterial phase hyperenhancement and washout appearance. However, these features...

Degradation mechanisms and long-term performance analysis of pile-group cap structures in sea-crossing bridges under corrosion and cyclic loading

Pile-group cap structures of sea-crossing bridges are exposed to marine chloride-induced corrosion and repeated lateral wave loading during their long-term service, which progressively deteriorates their structural performance. This study combines 1:10 scaled model tests with tim...

Architected Spatially Deterministic Multiscale Phase Segregation in Block Copolymer Composites for Augmented Radiative Cooling

ABSTRACT Passive radiative cooling, which reflects solar irradiation while emitting heat through the atmospheric window, provides a sustainable solution for zero‐energy thermal management. Simultaneously achieving high solar reflectivity and infrared emissivity remains challengin...

Effect of structure aspect ratio on the heat storage and extraction performance in an abandoned mine shaft

Combining solar energy with water tank thermal storage is a highly promising method for achieving cross seasonal storage and utilization of low-grade energy. However, the existing research mainly focuses on ground water storage, few investigations are involved in using abandoned...

Functional myocardial ischemia assessment based on HF-ECG microstructural features

Early detection and stratification of functional myocardial ischemia are critical for timely intervention but remain constrained by the limited sensitivity of conventional electrocardiography (ECG) and the cost and accessibility of imaging-based diagnostics. We present a non-inva...

Data‐Driven Vertiport Site Selection: A Two‐Stage Framework With Multi‐Source Urban Data and Scalable Optimization

ABSTRACT Urban Air Mobility (UAM) is increasingly recognized as a promising solution to alleviate urban congestion and improve transportation efficiency, playing a key role in developing sustainable urban infrastructure. A central challenge for UAM deployment is the siting of ver...