Sivas Cumhuriyet Üniversitesi

COMPARISON OF DRUG DELAYS FOR NEW DRUGS APPROVED IN TÜRKİYE WITH INTERNATIONAL AUTHORITIES

Objective: The pharmaceutical industry is constantly increasing in importance due to the ever-increasing need for health services, rising living standards, increasing average life expectancy, and advances in health technology. The approval of a new drug in the world varies from c...

Predictive value of urinalysis parameters for risk stratification of Staphylococcus aureus bacteremia in patients with Staphylococcus aureus bacteriuria

Aims Excluding bacteremia is clinically important in patients with Staphylococcus aureus bacteriuria (SABU), yet reliable predictors of concomitant S. aureus bacteremia (SAB) remain insufficiently defined. This study aimed to evaluate whether routine urinalysis parameters can pre...

Artifact-Controlled Multi-Vertebral Transfer Learning Ensemble for Patient-Level Three-Class Osteoporosis Screening Using Thoracoabdominal CT-Derived Lumbar Images

Background/Objectives: Osteoporosis and osteopenia remain underdiagnosed despite routine CT examinations containing potentially useful bone information. This study evaluated the feasibility of patient-level three-class classification of Normal, Osteopenia, and Osteoporosis classe...

Clinical characteristics and functional determinants of central sensitization in chronic neck myofascial pain syndrome

Background Central sensitization (CS) is a key mechanism in chronic pain, but its relationship with cervical muscle pressure pain thresholds (PPT) and disability in myofascial pain syndrome (MPS) remains unclear. Objective To investigate the clinical characteristics and functiona...

Early Neuroprotective Effects of Erucic Acid and Gentisic Acid on Hippocampal Glutamate Concentrations and Alzheimer-like Molecular Alterations in an Intracerebroventricular Streptozotocin Rat Model

Background: Alterations in glutamatergic homeostasis have been implicated in Alzheimer’s disease, but the relationship between total hippocampal tissue glutamate and Alzheimer-like molecular alterations remains unclear. This study evaluated the early neuroprotective potential of...

Algal Bioactive Metabolites with Important Roles in Wound Healing

A wound is defined as disruption or destruction of tissue integrity. In order to support healing in wound management, a good wound bed free of necrotic tissue and infection is desired, but intensive chemical antiseptics will cause cell destruction and delay healing. In order for...

Strategic human resource management, leadership, and governance practices in a university hospital: a qualitative study of healthcare managers’ experiences

Strategic human resource management, leadership, and governance are recognized as complementary management processes that play a fundamental role in enhancing organizational effectiveness and improving the quality of healthcare services. However, translating these processes into...

High School Teachers’ Views On the Utilization of 21st Century Learner And Teacher Skills

Purpose: The aim of this study is to determine the views of high school teachers on their use of 21st-century learner and teacher skills. Method: A case study design was employed in the research. The study group consists of 35 teachers working in high school institutions, selecte...

Tularemia in pediatric patients in Sivas Province: a 15-year clinical experience

Tularemia is a clinically important yet often underrecognized cause of persistent cervical lymphadenopathy in children living in endemic regions, and delayed diagnosis may lead to prolonged morbidity, inappropriate antibiotic use, and unnecessary invasive procedures. This study a...

Driver distraction detection using a perspective-integrated multi-task and multi-expert learning framework

Driver distraction is a leading cause of traffic accidents worldwide, making reliable driver monitoring essential for intelligent transportation systems. However, most deep learning-based approaches rely on a single camera perspective, which reduces robustness under occlusion, a...

Valorization of lemon peel waste into a polyacrylamide hydrogel composite for efficient adsorptive removal of Sunset Yellow FCF from aqueous media

Abstract The uncontrolled discharge of synthetic azo dyes into aquatic environments poses a serious threat to ecosystem integrity and public health, necessitating the development of sustainable and efficient remediation strategies. In this study, a novel bioderived hydrogel compo...

The role and importance of pericardial effusions in the diagnosis of malignancy

Objective: Pericardial effusion is a clinical condition characterized by the pathological accumulation of fluid within the pericardial cavity. It may develop secondary to cardiac, infectious, autoimmune, traumatic, or neoplastic processes. Malignancy-related effusions, particular...

Comparison of Whole‐Gland and Transition Zone PSA Density in Predicting Clinically Significant Prostate Cancer in PI‐RADS 3 Lesions

ABSTRACT Background PI‐RADS 3 lesions represent a clinical gray zone in prostate cancer diagnostics, often leading to unnecessary biopsies. Additional biomarkers are needed to improve risk stratification and safely exclude clinically significant prostate cancer (csPCa). This stud...

The Effect of Predilatation on Procedural Outcomes in Patients Undergoing Saphenous Vein Graft Percutaneous Coronary Intervention for Acute Coronary Syndrome

OBJECTIVE: Percutaneous coronary interventions (PCI) of saphenous vein grafts (SVG) are technically challenging due to friable plaques, high thrombus burden, and the risk of distal embolization. The impact of balloon predilatation on outcomes in patients presenting with acute cor...

Radiographic, histological, and immunohistochemical comparison of allograft, xenograft, and combined graft in maxillary sinus augmentation: a prospective randomized clinical study

This prospective randomized clinical trial aimed to compare the radiographic, histological, and immunohistochemical outcomes of allograft, xenograft, and combined graft use in maxillary sinus augmentation. Patients with a residual alveolar bone height ≤ 4 mm in the posterior maxi...

Comparative evaluation of nephrotoxicity and antibacterial activity of free and liposomal gentamicin in rats: Biochemical, molecular and histopathological analysis

Gentamicin is a widely used aminoglycoside antibiotic; however, its clinical use is limited by dose-dependent nephrotoxicity. Liposomal drug delivery systems may reduce toxicity while preserving antibacterial efficacy. This study aimed to comparatively evaluate the nephrotoxic an...

Trauma burden, coping patterns, and psychological symptoms in Ahiska Turkish children and adolescents displaced following the Ukraine war: a cross-sectional study

War-related displacement may affect youth mental health through direct trauma exposure, family-level trauma burden, and coping processes. Ahiska Turkish families displaced after the Ukraine war are a historically important group because recent displacement may occur against a bac...

Applying the International Classification of Functioning, Disability and Health to Classify Upper Limb Outcome Measures in Stroke Rehabilitation: A Construct-Driven Perspective

INTRODUCTION: Accurate evaluation of upper limb recovery after stroke is essential for guiding rehabilitation targeting specific impairments and activity limitations. To achieve this, outcome measures must clearly reflect what they assess, whether neuromuscular impairments or act...

The Effect of Mind and Intelligence Games on Executive Function and Problem Solving Skills in 60–72 Month Old Children

This study investigated the impact of a mind and intelligence game training program on the problem-solving and executive function skills of children aged 60–72 months. Utilizing a quasi-experimental design and quantitative research methods, the study involved 70 children: 36 in t...

Okul Yöneticilerinin Okul Web Sitelerini Yönetme Becerilerine Dair Görüşleri

Bu araştırmanın amacı, okul yöneticilerinin okul web sitelerini yönetme becerilerine ilişkin görüşlerini ortaya koymak ve bu platformların kurumsal tanıtım, bilgilendirme ve paydaşlar arası iletişimdeki rolünü incelemektir. Araştırma, nitel araştırma yöntemlerinden durum çalışmas...