Shiraz University of Medical Sciences

Musculoskeletal disorders and ergonomic risk factors among petrochemical control room operators with health promotion and intervention strategies

This study aimed to assess musculoskeletal and ergonomic risk, identify demographic, occupational, lifestyle, and biomechanical characteristics associated with these outcomes, and develop and prioritize ergonomic intervention strategies for petrochemical control room operators. T...

Performance of machine learning (ML) and deep learning (DL) algorithms in prediction of breast cancer distant metastasis via imaging: a systematic review and meta‑analysis

Distant metastasis is a major cause of breast cancer mortality. Early prediction may support risk-adapted surveillance and treatment planning. We evaluated imaging-based machine learning (ML) and deep learning (DL) models for predicting future distant metastasis in patients witho...

Antileishmanial potential of polar fractions from Amaranthus blitoides S. Watson, Caucalis platycarpos L., and Cistanche flava (C.A.Mey.) Korsh.: evidence from in vitro and in vivo studies

BACKGROUND: Cutaneous leishmaniasis (CL) is recognized by the World Health Organization (WHO) as a research priority, yet its treatment remains challenging. CL lesions arise from complex interactions between the parasite and host immunity, where excessive inflammation can delay h...

Evolutionary Divergence and Essentiality of the Single Tim17‐Centered Translocase of the Mitochondrial Inner Membrane in Trypanosoma brucei

ABSTRACT Translocase of the mitochondrial inner membrane (TIM) is essential for importing nuclear‐encoded proteins, a critical process for organelle biogenesis and function. While TIM is well‐characterized in a wide range of eukaryotes, it is remarkably divergent in the parasitic...

Exploring artificial intelligence usage preferences among medical students in Iran: a cross-sectional study

Abstract Artificial intelligence (AI) is increasingly integrated into medical education, offering opportunities to enhance learning, research, and clinical preparation. Although previous studies have explored medical students’ attitudes and acceptance of AI, evidence regarding th...

Posterosuperior and Anterior Rotator Cuff Repairs Yield Comparable 1‐Year Constant Scores in Routine Clinical Practice: A Propensity Score‐Matched Study From LaTour Group

Purpose To compare clinical outcomes and ultrasound‐assessed healing rates between posterosuperior and anterior rotator cuff repairs using propensity score matching. Methods Consecutive patients undergoing rotator cuff repair between 2015 and 2021 by a single fellowship‐trained s...

Synthesis and characterization of electrospun PCL-PVA-PPy-rGO fibers as a novel scaffold for bone tissue engineering

Electroconductive fibers based on Polycaprolactone (PCL) and Polypyrrole (PPy) possess considerable potential for bone tissue engineering due to their biocompatibility and biodegradability. However, low electrical conductivity in composites fabricated via direct blending of condu...

Old Drugs, New Targets: Molecular Docking Insights into Repurposing Proton Pump Inhibitors for the TLR4/MD-2, NLRP3, and C5aR1 Axes in Autoimmune Liver Diseases

Background/Objectives: Autoimmune liver diseases (AILDs), including autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis, may include treatment-resistant cases and therefore require new therapeutic strategies. This in silico study evaluated proton...

Health financing policy responses to economic crises in WANA countries: a systematic review (2008–2026)

Abstract Background The West Asian and North African (WANA) region has faced severe macroeconomic shocks over the past two decades, including sanctions, currency devaluation, and austerity measures, which critically threaten health system sustainability and equity. Objective This...

TNFAIP3 haplotypes modulate susceptibility to Behçet’s disease: evidence from an Iranian case-control study

Behçet’s disease (BD) is a chronic inflammatory disorder characterized by recurrent mucocutaneous, ocular, articular, and systemic inflammation. TNFAIP3 encodes A20, a negative regulator of NF-κB signaling, and its variants are implicated in immune-mediated diseases. This case-co...

Case report: Incidental finding of a duplicated right vertebral artery in a 17-year-old female with suspected systemic lupus erythematosus

We present the case of a 17-year-old female with suspected systemic lupus erythematosus (SLE), receiving prednisolone and hydroxychloroquine, who was evaluated for a difference in blood pressure between the upper extremities and an elevated erythrocyte sedimentation rate (ESR). C...

Effect of carnitine supplementation on quality of life: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials

The quality of life (QoL) is a multidimensional concept that its enhancement is a key goal in clinical and public health interventions. Evidence for the effect of carnitine on QoL is still contradictory. Therefore, the present study aims to systematically review the current evide...

Exploring the experiences of medical sciences faculty members and students in using artificial intelligence applications: a qualitative descriptive study

Abstract Background The rapid emergence of generative artificial intelligence (AI) is reshaping medical education worldwide. However, existing studies are predominantly quantitative and Western-centric providing limited empirical evidence regarding how medical sciences faculty me...

Association between salivary alkaline phosphatase levels and periodontal disease: a systematic review and meta-analysis

This updated meta-analysis evaluated salivary alkaline phosphatase (ALP) levels in individuals with gingivitis and periodontitis compared to periodontally healthy individuals. The review followed PRISMA guidelines and was registered in PROSPERO (CRD420251273461). Searches were co...

Diet quality of adult immigrants compared with non-migrants: a systematic review of quantitative studies

A vital aspect of health affected by immigration is diet quality. Previous investigations on this topic have yielded inconsistent results. This systematic review aims to summarize and organize research findings about diet quality among adult immigrants compared with non-migrants....

HER2-Low Breast Cancer: A Review of Epidemiology, Diagnostic Challenges, Targeted Therapies, and Clinical Outcomes

Background: Breast cancer is the most common malignancy among women. The HER2-low subgroup represents one of its prevalent subtypes; however, due to its unique characteristics, it presents challenges in diagnosis and treatment, complicating clinical management. This narrative rev...

Prevalence of depression in Iranian premenopausal and postmenopausal women and its association with sex hormone levels

Abstract Background Despite the global interest in depression as a disorder, few studies have been conducted on the association of female sex hormones and depression across different reproductive ages, and the findings have not been consistent to date. This study aimed to investi...

Neighborhood food environment density and cardiometabolic health in iranian adults: a cross-sectional study

Food environment (FE) density may influence cardiometabolic indices (CI), but findings remain inconsistent across anthropometric indices, lipid profiles, blood pressure, and glucose levels, while evidence from low- and middle-income countries remains limited. Therefore, this stud...

Prevalence of osteoporosis and its correlation with clinical variables in postmenopausal Iranian women with degenerative lumbar spinal stenosis: A cross-sectional pilot study

Objectives: This pilot study explored the prevalence of low bone mineral density (BMD) and its correlation with clinical variables in postmenopausal Iranian women with degenerative lumbar spinal canal stenosis (DLSS). Methods: This is a cross-sectional pilot study of 40 postmenop...

Emotional schema therapy training for improving resilience and emotion regulation in hemodialysis patients: a quasi-experimental study

Hemodialysis patients often experience chronic stress, leading to psychological challenges such as difficulty in emotion regulation and reduced resilience. Emotional schema therapy may offer an effective strategy to address these issues. This study investigated the impact of an e...