Shiraz University of Medical Sciences

Impact of Menopause and Menopausal Hormone Therapy on Liver–Kidney–Metabolic Health

Menopause is associated with unfavorable metabolic changes that may contribute to the development of metabolic dysfunction-associated steatotic liver disease (MASLD), chronic kidney disease (CKD), and increased cardiometabolic risk. Within the evolving cardiovascular-kidney-metab...

Beyond CAR-T: Multi-layered engineering strategies shaping the next generation of cellular cancer immunotherapy

Adoptive cellular immunotherapy has transformed the treatment landscape for hematologic malignancies; however, its broader application to solid tumors remains limited by antigen heterogeneity, inadequate persistence, restricted tumor infiltration, and the profoundly immunosuppres...

Milk-derived exosomes (MDEs) as emerging nanotherapeutics in regenerative medicine

Milk-derived exosomes (MDEs) are naturally occurring nanoscale extracellular vesicles with unique biocompatibility, stability, and intrinsic capacity to carry diverse bioactive cargoes such as proteins, lipids, and nucleic acids. Recent studies have underscored their remarkable t...

Evaluation of the Relative Citation Ratio Versus the H-Index as Measures of Citation-Based Scholarly Influence in Academic Neurosurgery

BACKGROUND AND OBJECTIVES: Evaluating citation-based scholarly influence among academic faculty is foundational to academic medicine, as retention, promotion, and tenure to govern career advancement at every level. The h-index has been the standard metric across fields, including...

Happiness and its correlation with spiritual well-being and attitude toward future career among medical students in Shiraz, Iran: a cross-sectional study

The present study aimed to determine happiness and its correlation with spiritual well-being and attitude toward future career among medical students. Although previous studies have investigated happiness, spiritual well-being, or career-related attitudes separately, and a limite...

Implant-Supported and Conventional Dentures: A Meta-Analysis in Older Adults

Statement of problem Edentulism is highly prevalent among older adults, with approximately 30% of adults aged ≥60 years affected by complete tooth loss in at least one dental arch. Conventional complete dentures (CCDs) often provide suboptimal retention and stability, negatively...

Monitoring of oxidative stress and acute phase proteins following testes exposure with ultrasound waves in cats

Ultrasonic therapy has harmfully effects on the structure and function of the testis. Various mechanisms are involved in the impact of ultrasound waves on testes tissue. This study aimed to investigate the effects of ultrasound exposure on cat`s testes by monitoring acute phase p...

Synthesis, characterization, and in vitro activity of piperine nanocrystals against protoscoleces of Echinococcus granulosus

Despite recent advances, current treatments for cystic echinococcosis (CE) still face challenges because of significant adverse effects and complications. This study investigates the synthesis, characterization, and in vitro activity of piperine nanocrystals (PIP-NCs) against E....

Predictors of academic self-efficacy in medical intern students: the roles of mindful eating, physical activity, sleep quality, and mental workload

Academic self-efficacy, defined as an individual’s belief in their capacity to complete academic tasks, may play a role in the learning and performance of medical students. Lifestyle factors such as sleep quality, physical activity, and mindfulness-based behaviors have been assoc...

Body Composition, Nutritional Status, and Dietary Intake in the First 100 Days After Stem Cell Transplantation and Their Link to One-Year Mortality in Leukemia Patients

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative treatment for acute leukemia; however, the first year after transplantation is associated with an increased risk of morbidity and mortality. This study aimed to evaluate changes in nutritiona...

Relationship between emotional indices and post-traumatic stress disorder in mothers with unsuccessful pregnancy

Unsuccessful Pregnancy is a traumatic life event that can lead to significant psychological consequences, including post-traumatic stress disorder (PTSD). Difficulties in emotion regulation, maladaptive emotion regulation strategies, and anxiety sensitivity have been identified a...

DESIGN AND PRELIMINARY EVALUATION OF A LOW-COST ACTIVE WALKER PROTOTYPE FOR INDIVIDUALS WITH LOWER-LIMB MOBILITY IMPAIRMENTS

This paper outlines the development and preliminary evaluation of a low-cost active walker, named Orthowalker, designed to assist individuals with mobility impairments in standing and supporting their gait. The powered walker was created as a motorized device with the MTK-RGO ort...