Shaqra University

Burden of CNS neoplasms in the Middle East and North Africa from 1990 to 2023, with projections to 2050

Central nervous system (CNS) neoplasms are uncommon but highly consequential malignancies that account for substantial neurological disability and premature mortality. The Middle East and North Africa (MENA) region is marked by rapid population growth, aging, and uneven health sy...

Encountering antibiotic resistance: Current challenges and emerging solutions in the post-antibiotic era

Antibiotic resistance has become one of the greatest threats to global health in this century, causing many health problems in many countries. In contrast, the multidrug-resistant (MDR) bacterial strains developed mechanisms to encounter surrounding toxic compounds in their envir...

ECO-EDGE: joint DAG offloading and fabric routing in Multi-AP MEC via conic optimization

Mobile Edge Computing (MEC) enables low-latency services by migrating computational resources closer to end-users. However, as mobile workloads increasingly adopt complex Directed Acyclic Graph (DAG) topologies, system performance is strongly affected by interdependent data shuff...

From classroom to labour market: assessing the role of digital accounting education in fostering learning outcomes and employability skills

Purpose This study investigates the relationships between digital accounting education (DAE), students' learning outcomes, and employability skills, with particular attention to the role of institutional support in shaping the association between academic preparation and labour m...

A data driven assessment of structural barriers to electrical equipment manufacturing in Bangladesh: trade dependency, industrial competitiveness, and policy pathways

The rapid expansion of Bangladesh’s power and industrial sectors has led to a significant increase in demand for electrical equipment, a large portion of which is currently fulfilled through imports, resulting in sustained foreign currency outflows and supply chain vulnerabilitie...

Blockchain, Artificial Intelligence, and ESG Disclosure Quality: The Moderating Roles of Financial Regulation and Stakeholder Engagement

Environmental, social, and governance (ESG) disclosure quality remains constrained by fragmented data, limited verifiability, and inconsistent reporting practices. This study examines whether artificial intelligence and blockchain are associated with perceived ESG disclosure qual...

Advanced machine learning techniques for daily streamflow forecasting: a case study of the Brahmaputra River

Accurate multi-day streamflow forecasts support flood preparedness, but single holdout scores can conceal lead-time dependence, temporal instability, baseline skill, and uncertainty. This study compares Long Short-Term Memory, Random Forest, Multiple Linear Regression, Multi-Laye...

Metabolic perturbations associated with ADAT3 variant–related intellectual disability revealed by untargeted metabolomics

Untargeted metabolomics is a powerful analytical approach for characterizing global metabolic alterations associated with physiological and pathological states. This approach is particularly valuable for rare genetic disorders, where metabolic consequences are poorly understood a...

Nurses’ Perceptions and Behaviors Regarding Climate Change and Health: A Correlational Study Aligned With Saudi Vision 2030

ABSTRACT Climate change is an escalating threat to population health, placing increasing pressure on healthcare systems. Nurses play a pivotal role in delivering climate‐resilient healthcare; however, evidence regarding their perceptions and climate‐related health behaviors in Sa...

Arduino-controlled pulse electrodeposition for low-cost zinc coating on stainless steel

<title>Abstract</title> Metal corrosion is a major challenge in the manufacturing sector. Pulse electrodeposition (PED) is a promising effective technique for metal corrosion protection; however, the coating quality depends on the PED parameters. This study involved metal corrosi...

Shared and Distinct T-Cell Receptor Characteristics of CD4+ and CD8+ Drug-Specific T-Cells In Vitro Generated from Healthy Donors and Hypersensitive Patients

Abstract The initiation of T-cell-mediated drug hypersensitivity reaction requires the formation of a human leukocyte antigen (HLA)-peptide-drug-T-cell receptor (TCR) complex. While specific interactions between HLA molecules and drug antigens are well-defined, the characteristic...

Variance-Adaptive Self-Regularizing Ensemble Learning for Robust Predictions in Small-Data Regimes

The small-data regime remains one of the most important and pressing problems in machine learning. With only a few hundred sample points in the training set, conventional ensemble methods are potentially unreliable because they have high variance, low generalization and are sensi...

Oxidative Stress-Associated Apoptotic Responses Induced by Lantana camara L. Flower–Derived Zinc Oxide Nanoparticles in Human Non-Small Cell Lung Cancer (NCI-H460) Cells

Lung cancer remains a leading cause of cancer-related mortality worldwide, underscoring the need for safer and more effective therapeutic strategies. In this study, zinc oxide nanoparticles (ZnO NPs) were synthesized via a green, biogenic approach using Lantana camara L. flower a...

Synthesis, modelling, biological activity of new thiophene hybridized with pyrazole, and/or pyridine analogues as potential DNA gyrase and topoisomerase IV inhibitors

Promoted by the well-established, valuable biological activity of thiophene-based hybrids, the study displayed the synthesis of two series of thiophene-pyrazole hybrids, 7a-c and thiophene-pyridine hybrids 9a-c, via reacting arylhydrazone with halogenated reagents and nucleophili...

Green synthesis of Ni-doped ZnO nanoparticles using Salvia hispanica and their antibacterial, anticancer and anti-virulence activities

An environmentally benign approach was employed to synthesize nickel-doped zinc oxide (Ni–ZnO) nanoparticles employing Salvia hispanica extract as a biologically derived reductant and capping material. Phytochemical profiling confirmed the abundance of phenolic and flavonoid comp...