Shahrekord University of Medical Sciences

Targeting ferroptosis in cancer: molecular mechanisms and emerging therapeutic strategies

Ferroptosis, an iron-dependent form of regulated cell death characterized by the lethal accumulation of lipid peroxides, has emerged as a pivotal pathway in cancer biology and a promising therapeutic target. This review synthesizes the core molecular machinery governing ferroptos...

Neighborhood food environment density and cardiometabolic health in iranian adults: a cross-sectional study

Food environment (FE) density may influence cardiometabolic indices (CI), but findings remain inconsistent across anthropometric indices, lipid profiles, blood pressure, and glucose levels, while evidence from low- and middle-income countries remains limited. Therefore, this stud...

Feedback loops as a core driver: rethinking organizational readiness for knowledge translation in Iranian medical universities

Bridging the gap between research evidence and healthcare decision-making, knowledge translation (KT) is a critical process. However, despite advances in research production, many universities in low- and middle-income countries face significant challenges in implementing KT due...

Barriers to mental health screening in Iran’s primary healthcare system and its implications for service improvement

Introduction Mental disorders impose an increasing burden on healthcare systems, particularly in low- and middle-income countries (LMICs). Although Iran integrated mental health services into primary healthcare in the 1980s, screening implementation remains challenging. This stud...

Fabrication and performance assessment of a new dry in-ear EEG sensor for brain monitoring

Bioelectrodes are commonly utilized for sensing electrical signals from the electrochemical activity of excitable cells, recording ionic currents from the body, and translating them into detectable electrical signals. Conventional scalp EEG electrodes, nonetheless, are subject to...

Incremental Prognostic Value of CT Indices Derived from Midline Shift and Hematoma Thickness in Acute Subdural Hematoma

Background: In acute subdural hematoma (ASDH), early risk stratification relies heavily on hematoma thickness (HT) and midline shift (MLS). Composite indices derived from these measures have been proposed to better characterize mass effect, but their incremental prognostic value...

Relationship between common non-communicable diseases (NCDs), risk factors and happiness in Shahrekord PERSIAN Cohort Study: a path analysis model in Iran

Happiness is an important component of subjective well-being and has been increasingly recognized as a determinant of health. Although growing evidence suggests associations between happiness, health status, and chronic diseases, the complex pathways linking happiness with non-co...

Causes of moral distress in students of the Faculty of Medical Sciences: a qualitative study

Ethical challenges in the educational environment can create conditions for moral distress in students and negatively affect their quality of learning and academic performance. The purpose of the study was to explain the experiences of students regarding the causes of moral distr...

The association between stress hyperglycemia ratio and adverse outcomes in patients with chronic kidney disease: a systematic review and meta-analysis

Chronic kidney disease (CKD) increases risks of cardiovascular events and mortality, so reliable biomarkers are needed to improve risk stratification. Stress hyperglycemia ratio (SHR), which adjusts acute glucose levels for chronic glycemia using glycated hemoglobin, has shown pr...

Comparing the analgesic effect of fluoxetine plus vitamin e with vitamin e alone on mastodynia due to fibrocystic breast disease: a randomized double-blind clinical trial

Mastodynia is a common symptom in women with fibrocystic breast disease and can substantially impair quality of life. Although vitamin E is frequently used for symptom relief, the potential additional analgesic effect of fluoxetine remains unclear. This study aimed to compare the...

Cognitive performance evaluation under exposure to heat and light color temperature: a bayesian network modeling approach in laboratory conditions

Indoor environmental quality significantly affects cognitive performance in educational and occupational settings. While the effects of ambient temperature and correlated color temperature (CCT) have been independently investigated, their mixed effect remains unclear. This experi...