Shahid Sadoughi University of Medical Sciences and Health Services

Maternal oral health indicators during pregnancy and childhood allergic outcomes up to three years: a retrospective analysis of a prospective cohort study

Maternal oral health during pregnancy may be associated with offspring allergic outcomes, but evidence linking specific oral health indicators to childhood allergy is limited. We examined associations between maternal oral health indicators during pregnancy and questionnaire-asce...

Staging and grading without data: rethinking periodontal classification in low-resource settings — a critical mini-review

The 2017 World Workshop introduced a staging and grading framework intended to improve diagnostic consistency and support individualized periodontal care. Although conceptually robust, its practical application depends on clinical, radiographic, and systemic data that are not con...

Chlorhexidine MIC distribution, efflux pump gene profiles, and genotypic characteristics among clinical methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates

Reduced antiseptic susceptibility mediated by multidrug efflux pumps in drug-resistant Staphylococcus aureus poses an additional infection control concern. This study investigated chlorhexidine susceptibility status and efflux pump gene distribution across different accessory gen...

Resilience, self-efficacy, and professional quality of life among emergency department nurses: a cross-sectional study

Nurses, as frontline healthcare providers in crisis and emergency settings, are frequently exposed to high levels of occupational stress. Resilience and self-efficacy are considered important psychological resources that may influence nurses’ professional quality of life and psyc...

Risk factors for seroma formation following abdominoplasty: a systematic review and meta-analysis

Abstract Background Seroma is the most common complication following abdominoplasty. However, the risk factors associated with its development remain unclear, with inconsistent findings across studies. Objective To systematically evaluate and quantitatively synthesize risk factor...

Association of professional ethics adherence and moral comfort among intensive care unit nurses

Moral comfort is essential for intensive care nurses facing ethical situations and complex clinical decisions. Adhering to professional ethical standards in nursing care may contribute to the development of moral comfort. This study was conducted to investigate the relationship b...

Effect of leukemia inhibitory factor on immune checkpoint-related gene expression: a possible new window to overcome recurrent pregnancy loss and boost immune system tolerance

Recurrent pregnancy loss (RPL) is an essential issue in reproductive science that affects 1–3% of women. Immune checkpoint molecules play crucial roles in successful pregnancies. This study investigates the effect of leukemia inhibitory factor (LIF) on immune checkpoint-related g...

Trauma patterns and epidemiological characteristics among older adults: a retrospective registry-based study in Iran

Geriatric trauma involves injuries in older people. It significantly contributes to illness and death, with older adults facing unique health challenges and risks. The present study aimed to describe trauma patterns and epidemiological characteristics of older adults patients adm...

Exploring factors contributing to road traffic injury mortality across the trauma care continuum: a qualitative study

Road traffic injuries (RTIs) are a major cause of premature mortality, particularly in low- and middle-income countries. Although injury severity is a key determinant of outcomes, delays and deficiencies across the trauma care continuum may also contribute to mortality. However,...

Socioeconomic disparities in urban exposome in pregnant women in Yazd Birth Cohort study

Urban exposome during pregnancy have a significant impact on both maternal and child health, and socioeconomic status (SES) can further exacerbate these disparities. We conducted an analysis of data from 2,902 pregnant women within the Yazd Birth Cohort, a subset of the PERSIAN B...

Development and validation of a questionnaire for diabetes prevention behaviors based on the behavior change wheel framework in Iranian adults with prediabetes

The rising prevalence of prediabetes necessitates theory-based instruments to assess behavioral determinants and guide prevention. This study developed and validated a questionnaire based on the Behavior Change Wheel (BCW) for Iranian adults with prediabetes. This cross-sectional...

Effects of grape seed extract on immune-related gene expression, inflammatory biomarkers, disease activity, and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled trial

Abstract Grape seed extract (GSE), a polyphenol-rich nutraceutical with antioxidant and anti-inflammatory properties, has shown promising effects in preclinical colitis models; however, clinical evidence in patients with ulcerative colitis (UC) remains limited. This study provide...

Oral mucositis severity as an indicator of supportive care adequacy among women undergoing breast cancer in Yazd, central Iran: a cross-sectional study

Abstract Background Oral mucositis is one of the most painful side effects women face during breast cancer treatment, yet it is frequently overlooked in routine clinical care. Despite the existence of clear prevention and management guidelines, many patients endure progressive or...

The relationship between caring behaviors, professional dignity, and suicidal ideation among clinical nurses: a cross-sectional study

Caring behaviors are fundamental to nursing practice and patient safety. Professional dignity and suicidal ideation have been suggested as factors associated with caring behaviors; however, evidence regarding their simultaneous roles remains limited. This study examined the assoc...

Associations of major depressive disorder, generalized anxiety disorder, obsessive-compulsive disorder, and aggression with subclinical variations in kidney function biomarkers among young adults: A cross-sectional study from the rafsanjan youth cohort study

Psychiatric disorders emerging during adolescence and young adulthood may be associated with variations in physiological systems beyond the brain, including kidney function biomarkers. However, most previous research examining psychiatric disorders and kidney-related outcomes has...

The dietary inflammatory index and its associations with sleep, mental health, quality of life and aggressive behavior in Iranian female adolescents

The relationship between the inflammatory potential of foods and sleep, mental health, quality of life and aggressive behaviors is not well understood in Iranian female adolescents. We aimed to address this since there is a high prevalence of these factors in this population. In...

Cross-platform transcriptomic integration identifies PDPN for precision prognostic stratification of 1p/19q non-codeleted adult diffuse gliomas

Molecular stratification is central to precision oncology, enabling targeted diagnosis and risk-adapted management of glioma. However, clinically robust transcriptomic biomarkers that refine molecular risk stratification according to 1p/19q status and support personalized diagnos...

Intermittent fasting in diabetic retinopathy: microbiome modulation, mechanisms, and clinical insights.

Intermittent fasting, a nonpharmacological approach, shows promise for controlling diabetic retinopathy but lacks concrete human evidence directly associating intermittent fasting with eye responses. This review highlights preclinical research insights about intermittent fasting...

Improvement in functional movement, landing mechanics, and dynamic balance following TRX training in physically active athletes after ACL reconstruction: a randomized controlled trial

Abstract Purpose Anterior cruciate ligament (ACL) rupture is one of the most prevalent and critical injuries experienced by athletes. The purpose of the present study was to examine the effects of a six-week TRX suspension training program on movement quality, landing mechanics,...

Relationship between urinary and water fluoride with cardiovascular risk factors in children and adolescents in Yazd city

Abstract Background Although the prevalence of cardiovascular diseases is low during childhood and adolescence, behavioral and biological risk factors and lifestyle associated with noncommunicable diseases are formed during this period and persist into adulthood. The present stud...