Shahid Beheshti University

Association of total and source-specific dietary nitrate and nitrite with subclinical atherosclerosis in young adults

Atherosclerosis, a chronic process originating in young adulthood and progressing silently to clinical cardiovascular disease, highlights the need to identify modifiable nutritional exposures. Epidemiological evidence regarding their association with subclinical atherosclerosis i...

Machine learning-assisted design of a novel crocin-loaded poloxamer 407/hyaluronic acid in situ forming hydrogel for endometriosis treatment: in vitro characterization and in vivo efficacy evaluation

Our study focused on fabricating and characterizing a crocin in situ forming hydrogel for endometriosis treatment. An artificial neural network (ANN)-based machine learning (ML) approach was employed to determine the effects of poloxamer 407 (P407) and hyaluronic acid (HA) concen...

Artificial intelligence and machine learning applications in Behçet’s disease: a scoping review protocol

Abstract Background Behçet's disease (BD) is a chronic multisystem vasculitis of unknown aetiology with a characteristic geographic distribution along the historic Silk Road, with highest prevalence in Turkey, Iran, and surrounding regions. Diagnosis remains clinical and often de...

Diagnostic accuracy of droplet digital PCR for BRAF mutation detection in thyroid specimens: a systematic review and meta-analysis

BRAF mutation testing, particularly for BRAF V600E, may provide adjunctive diagnostic information in the evaluation of thyroid nodules when interpreted alongside cytology, ultrasonography, and clinical risk. Droplet digital polymerase chain reaction (ddPCR) enables sensitive dete...

Scale-up failure in startups: a multi-level framework

Purpose This study aims to investigate the main factors contributing to startup failure during the scale-up stage. It attempts to create a multi-level framework that illustrates how individual, organizational, industrial and institutional factors collectively influence failure ou...

Beyond Alliance Scores: Construct Transport and Measurement Validity in Mental Health Chatbot Research—A Systematic Scoping Review

Therapeutic alliance is increasingly measured in mental health chatbot research, although many instruments originated in human psychotherapy. This systematic scoping review examined alliance conceptualization, operationalization, adaptation, and evaluation with artificial convers...

Harnessing nanomedicine for breast cancer therapy through the immunomodulatory activity of BCc1

Although BCc1 represents a novel nanochelating-based nanomedicine, its route- and dose-dependent impacts on mammary oncogenesis, immunoregulation, and non-coding RNA (ncRNA) dynamics remain poorly defined. Here, female BALB/c mice bearing subcutaneous 4T1 mammary carcinomas were...

Optimizing alginate-based delivery systems to enhance adipose-derived stem cell functionality in regenerative medicine: a comprehensive review

This review explores the potential of alginate-based delivery systems for adipose-derived stem cells (ASCs) in regenerative medicine, with a focus on recent strategies that enhance ASC survival, functionality, and therapeutic efficacy. A structured literature analysis was perform...

Effects of adding gait retraining with visual feedback to resistance-balance training on kinematics, centers of pressure, and proprioception in individuals with chronic ankle instability: a randomized controlled trial

Abstract Background Chronic ankle instability (CAI) causes biomechanical alterations and leads to repeated ankle injuries, impairing daily activities and sports performance. Limited evidence exists on the combined effects of gait retraining with visual feedback added to resistanc...

Aeroelastic optimization of a small scale horizontal axis wind turbine using particle swarm algorithm

Abstract The multi-objective optimization of a horizontal axis wind turbine blade is performed to optimize its aerodynamic and structural performance by coupling two-way fluid–structure interaction (FSI) with a multi-objective particle swarm optimization (MOPSO) algorithm. The de...

Loving pedagogy and foreign language teaching enjoyment as predictors of Iranian EFL teachers’ engagement in reflective practice

The present study examined the relationships among loving pedagogy (LP), foreign language teaching enjoyment (FLTE), and engagement in reflective practice (RP) among Iranian EFL teachers working across various educational contexts. Data were collected from 130 EFL teachers (89 fe...

Integration of gene expression profiling and triterpenic acids content reveals optimal harvesting seasons in Salvia rosmarinus

Rosemary ( Salvia rosmarinus Spenn.) is one of the most important medicinal and aromatic plants of the Lamiaceae family, widely used in food, pharmaceutical, cosmetic, and hygienic industries. The plant is rich in triterpenic acids including betulinic, oleanolic, and ursolic acid...

Mesoporous silica nanoparticles as an advanced tool for cancer therapy

Mesoporous silica nanoparticles (MSNs) are becoming popular for targeted drug delivery because their pore structure can be changed, they have a large surface area, and their surface can be easily modified. This review critically assesses recent advancements in MSN-based drug deli...

Dielectric barrier discharge cold plasma inactivation of Ephestia kuehniella and quality assessment of wheat flour

Abstract This study investigated the effectiveness of cold dielectric barrier discharge (DBD) plasma for controlling different developmental stages of the Mediterranean flour moth ( Ephestia kuehniella) in wheat flour. Eggs, larvae, and pupae were treated under different voltage...

Extensive head and neck necrotizing fasciitis induced by mandibular canine tooth infection in an uncontrolled diabetic patient: a case report

Abstract Background Head and neck necrotizing fasciitis is a rare, progressive soft tissue infection that usually originates from odontogenic sources. Systemic diseases, including immunosuppression and diabetes mellitus, can complicate patient management. Case presentation We rep...

Antibacterial evaluation of sophoraflavanone G from Sophora pachycarpa against Pseudomonas aeruginosa and Staphylococcus epidermidis biofilm

Abstract Antimicrobial resistance, particularly among biofilm-forming pathogens, poses a serious threat to public health and drives the urgent need for new therapeutic agents. Sophoraflavanone G, a prenylated flavonoid derived from Sophora pachycarpa , has shown notable antimicro...

How Norms Depend on the Presence and Status of Observers: The Relational Contingency of Everyday Behaviors in 90 Societies

Norms are fundamental to social life, but basic questions about how they are affected by social context remain. Specifically, how do normative constraints depend on the presence and status of observers, and how do such relational contingencies vary across cultures? Using data fro...

Plyometric-jump training with versus without unstable load to improve physical fitness in trained young volleyball players: a randomized controlled trial

Abstract Background Plyometric-jump training (PJT) has been recommended as an effective resistance training modality for enhancing vertical jump and lower limb muscle power in young athletes. While unstable surfaces are popular means to address progression and specificity, an alt...

Evaluation of the oxidative conversion of benzothiophene and dibenzothiophene in a model fuel using DBD plasma and a TiO2/MCM-41 catalyst

This study investigates the oxidative conversion of benzothiophene (BT) and dibenzothiophene (DBT) at room temperature using ozone generated by dielectric barrier discharge (DBD) plasma, with and without a synthesized TiO 2 /MCM-41 catalyst. Unlike most previous DBD-plasma-assist...

Patterns of information flow in autism canonical brain network by transfer entropy approach

Abstract The functional brain activity network is the result of the harmonious activity of different regions. Each harmonic activity requires feedback from different areas of activity to adjust itself. As a result, any disorder in this harmony can affect the functional brain acti...