Selçuk University

Tryptophan metabolism and erectile dysfunction: pathophysiological insights into kynurenine pathway dysregulation

Abstract Background ED refers to the persistent difficulty in attaining or sustaining a firm enough erection for satisfactory sexual performance. The kynurenine pathway (KP) of tryptophan metabolism is associated with reactive oxygen species production and inflammation and may be...

Associations Between Sleep-Related Characteristics and Mind Wandering in Adults with ADHD: A Cross-Sectional Study with a Control Group

Excessive mind wandering is increasingly recognized as a clinically relevant cognitive feature of adult attention-deficit/hyperactivity disorder (ADHD), yet its relationship with sleep-related characteristics remains insufficiently understood. This cross-sectional study with a co...

Understanding task-specific AI adoption among academic professionals: AI literacy, professional role, and responsible use

Artificial intelligence (AI) tools are increasingly embedded in academic work; however, little is known about why academics adopt them for some tasks but not others. Drawing on technology adoption, professional identity, ethical decision-making, and professional technology-use pe...

Pharmacogenetic hypersensitivity to somatropin in a child with severe growth hormone deficiency and MC4R p.V166I variant

Abstract Objectives The melanocortin-4 receptor (MC4R) is a G protein–coupled receptor that regulates energy homeostasis. Pathogenic MC4R variants represent the most common cause of monogenic obesity and are frequently associated with increased linear growth. However, the mechani...

Associations between parental feeding practices, maternal stress, and body mass index in children aged 3–11 years

Childhood obesity remains a major public health concern, with early-life nutritional environments and family-related factors playing important roles in children’s weight outcomes. Parental feeding practices and maternal psychological well-being have been associated with children’...

Impact of magnification and fluorescence guidance on conservative retrieval of failed fiber posts: an in vitro study

Abstract Background Fiber post removal during endodontic retreatment is challenging since fiber posts bond strongly to root dentin, closely matching its color, making the post–cement–dentin interface difficult to distinguish. Consequently, fiber post retrieval may cause unnecessa...

Cue-specific sexual avoidance, metacognitive beliefs, and sexual functioning in women with lifelong vaginismus: a cross-sectional case–control study

Abstract Background Avoidance is a key maintaining factor in lifelong vaginismus and may extend beyond penetration attempts to broader sexual cues. Metacognitive beliefs, particularly beliefs about the usefulness of worry and the uncontrollability and danger of thoughts, may shap...