Samarkand State University named after Sharof Rashidov

Cell-free DNA fragmentomics and epigenomic profiling in hematologic malignancies: current evidence, translational limitations, and future directions

Mutation-based liquid biopsy supports diagnosis and disease monitoring in hematologic malignancies, but interpretation of plasma variants may be complicated by clonal hematopoiesis, treatment-related changes, and nonmalignant blood-cell turnover. This structured narrative review...

Inverse Kernel Identification in a Time‐Fractional Integro‐Differential Equation

ABSTRACT This article investigates a fractional diffusion‐wave model incorporating memory effects. We first analyze the direct problem and establish the existence, uniqueness, and regularity of its solution under suitable conditions. The primary focus is on an inverse problem, in...

Bony labyrinth taxonomic identification and long-term evolution of livestock in the Southwest and Central Asia

Abstract Southwest and Central Asia were pivotal regions for the domestication and dispersal of domestic herbivores. Here we investigate long-term variation in bony labyrinth morphology of domestic bovids (sheep, goats and cattle) across the last 10 000 years. We focused on the o...

Charge-Carrier Behavior and Molecular Interface Engineering in Perovskite Light-Emitting Diodes

Abstract Molecular interface engineering has become increasingly important for improving the efficiency and stability of perovskite light-emitting diodes (PeLEDs). Although highly emissive perovskite materials have advanced rapidly, their translation into high-performance devices...

A Cache-Aware Compression Framework: Deriving the Compression Target and Stopping Rule for Transformers on CPU-Class Hardware

In post-training compression of Transformer models, the compression ratio or pruning rate is often predetermined and does not directly take into account the memory capabilities of the target hardware. This work introduces a cache-aware post-training compression framework for CPU-...

Interfacial-coupling-driven 2D Ni(OH)2/SnO2 hybrid heterostructures for carbon-free, durable supercapacitor electrodes

Low-cost, carbon-free electrodes that stay stable over long cycling are hard to make without conductive scaffolds such as graphene or carbon nanotubes. We report 2D Ni(OH) 2 /SnO 2 hybrid nanostructures prepared by a single-step hydrothermal route, in which ultrathin β-Ni(OH) 2 n...

Pb(II) Selectivity of Oxygen-Functionalized Lignite-Based Carbon Material in the Presence of Competitive Cu(II)/Cd(II) Interference

Abstract A series of lignite-derived activated carbons (CK-400-CK-700) was prepared by KOH activation to clarify the effects of pore structure and surface oxygen functionality on Pb(II) adsorption. Although the BET surface area increased from 456.60 to 1300.70 m2·g–1 with activat...

Is AI adoption a pro-environmental choice? Integrating value-belief-norm theory and theory of planned behavior

Purpose Artificial intelligence (AI) could be essential to helping organizations improve efficiency and enable quick, accurate decision-making. This study investigates the adoption behavior of AI technology from an ecological perspective. Using the value-belief-norm (VBN) and the...

Ruppeiner thermodynamic geometry, microstructure, quasinormal modes and greybody factors of the Einstein–Skyrme black hole

Abstract We investigate the thermodynamic microstructure, quasinormal mode spectrum, and greybody factors of the exact, static, spherically symmetric black hole in Einstein–Skyrme theory, building on the recently established first law that promotes the Skyrme couplings K and $$\l...

Flexible Late Mousterian lithic technological organisation at Riparo l’Oscurusciuto (Italy): A typo-technological and 3D-based approach

Abstract The portion of the Riparo l’Oscurusciuto (Italy) stratigraphic sequence so far excavated provides an outstanding record of the local population history between ca. 55 − 42 kya BP: a key period for understanding the end of the Middle Palaeolithic and the onset of the Uppe...

Altitudinal patterns of soil nematode community diversity and functional structure in the Boysun Mountains, Uzbekistan

Mountain ecosystems provide natural gradients for investigating biodiversity responses to environmental variation. This study examined the effects of altitude on the taxonomic diversity, trophic structure, and functional composition of soil nematode communities in the Boysun Moun...

Altitudinal patterns of soil nematode community diversity and functional structure in the Boysun Mountains, Uzbekistan

Mountain ecosystems provide natural gradients for investigating biodiversity responses to environmental variation. This study examined the effects of altitude on the taxonomic diversity, trophic structure, and functional composition of soil nematode communities in the Boysun Moun...

ANALYSIS OF INDICATORS OF HUMAN CAPITAL UTILIZATION AND LABOR RELATIONS EFFICIENCY IN THE SMALL BUSINESS SECTOR

The article provides a statistical and economic analysis of the system of indicators characterizing the utilization of human capital and the efficiency of labor relations in the small business sector of Uzbekistan. A methodological distinction is made between the existing stock o...

Independent Engineering Transfer After Traceable Generative-AI-Assisted Learning: A Six-University Controlled Trial with Deterministic Cluster Allocation in Agricultural Engineering Education

Generative artificial intelligence (GenAI) can support engineering problem solving, but whether AI-assisted practice transfers to independent performance after the tool is removed remains unclear. This multicentre controlled trial evaluated a traceable five-stage GenAI-assisted l...

A De Giorgi conjecture on the regularity of minimizers of Cartesian area in 1D

Abstract We prove a $$C^{1,1}$$ C 1 , 1 -regularity result for minimizers of the functional $$ \int _I \sqrt{1+|Du|^2} + \int _I |u-g|ds,\quad u\in BV(I), $$ ∫ I 1 + | D u | 2 + ∫ I | u - g | d s , u ∈ B V ( I ) , provided $$I\subset \mathbb {R}$$ I ⊂ R is a bounded open interval...

The Emergence of Pottery in Southern Iran: Evidence from the Neolithic Site of Tol-e Sangi

Abstract The emergence and spread of pottery production in Southwest Asia is a key topic in Neolithic archaeology, as it can provide valuable information about the technological developments and cultural changes of early societies. Archaeological excavations at the Tol-e Sangi in...

Circular-orbit dynamics and QPO constraints in static Einstein–scalar–Gauss–Bonnet black holes

Abstract Einstein–scalar–Gauss–Bonnet (EsGB) gravity provides a physically motivated framework for testing strong-field deviations from the Schwarzschild geometry through scalar hair. We study neutral-particle circular motion and high-frequency quasi-periodic oscillations (HF-QPO...

Neanderthal’s heel: How the Neanderthal’s external calcaneal shape uniquely differs from that of modern humans

Neanderthals exhibit unique morphological adaptations in their calcaneus compared to Homo sapiens , shedding light on distinct evolutionary pressures and functional requirements shaping their respective foot anatomy. This study assesses which calcaneal traits represent plesiomorp...

Earliest simultaneous multi-color optical observations of GRB 230328B: from 41 seconds to the host-galaxy identification

Abstract We present a multiwavelength study of the long-duration gamma-ray burst GRB 230328B, combining prompt γ-ray observations with exceptionally early simultaneous optical photometry and extensive X-ray, radio, and host-galaxy follow-up. NUTTELA-TAO began simultaneous g′r′i′...

Assessment of the Dissipative Properties of Viscoelastic Hollow Cylindrical Bodies with Filler During the Propagation of Natural Waves

Searching by numerical simulation for structures with optimal damping properties among viscoelastic hollow cylindrical bodies with a filler is usually associated with a large amount of computation. Formulating the mechanical problem as one of natural vibrations and natural wave p...