Saarland University

Mind the Trust Gap: Identifying (Mis)alignments in Teacher-Student Views Toward Control and Agency in K-12 Classroom AI

As Artificial Intelligence (AI)-based technologies have been integrated into school classrooms where multiple stakeholders (with different roles) interact with each other, it is critical to deeply understand stakeholder views in the classroom. In particular, prior work has not fu...

Real-World Clinical Management of Keratoconus in Europe and the Middle East: A Multicountry Survey on Diagnostic and Surgical Practices (Keratoconus in Mind - KIM Project)

Purpose: This study aimed to describe the current management of patients with keratoconus in European and Middle Eastern countries through the collection of real-world data from clinicians actively managing keratoconus. Methods: Computer-assisted web interviewing survey targeting...

German translation and initial measurement properties of the Q-TFA in transfemoral bone-anchored prosthesis users

Abstract Background To translate and cross-culturally adapt the Questionnaire for Persons with a Transfemoral Amputation (Q-TFA) into German and evaluate initial measurement properties in adults with unilateral transfemoral amputation using a transcutaneous bone-anchored prosthes...

Psychotherapy remission prediction models show limited cross-clinic generalizability in routine outpatient care

Abstract Clinical prediction models for psychotherapy outcomes have the potential to assist therapists in planning a patient’s individual treatment, but their clinical utility depends on maintaining predictive performance across settings. We assessed prediction of post-treatment...

Chemical Switching Between B 2 N and B 2 C Homoaromaticity

ABSTRACT In homoaromatic species, the formal replacement of one or more bonds of the σ‐framework by saturated fragments (the homo bridge) can lead to geometry distortions that preserve a certain degree of cyclic π‐conjugation. While cationic and anionic homoaromatics are well‐est...

A hydration-dependent minimum in finger pad friction on rough surfaces

Abstract Finger pad friction is central to object manipulation and tactile perception, and surface roughness is a key parameter for its control. In a systematic investigation of finger pad friction on aluminum surfaces with varying roughness, measurements from 61 participants rev...

Who Achieves Long‐Term Goals? Development and Validation of the DPR Conceptualization of Trait Self‐Control and the DPR Self‐Control Scale

ABSTRACT Objective Trait self‐control predicts many desirable life outcomes ranging from health to wealth. Yet, conceptual issues around the construct (e.g., how to integrate coexisting perspectives or acknowledge the variability of individual goals and dominant tendencies) seem...

Prosodic features of second language fluency

Abstract Fluency has often been ignored in speech prosody research, including in research on prosody of a second language (L2). However, a broader view on L2 sentence prosody would be beneficial to the construction of theories concerning the acquisition of L2 prosody and applicat...

DockM8: an all-in-one open-source platform for consensus virtual screening in drug design

Virtual screening remains a critical step in structure-based drug design, yet variability in docking algorithms and scoring functions often limits its reliability. To address this challenge, we introduce DockM8, an open-source platform for consensus virtual screening that integra...

Resistance-interval training combined with Chlorella vulgaris supplementation modulates PCSK9, ghrelin, adropin, and MANF in obese men: a randomized controlled trial

Obesity disrupts lipid metabolism, appetite regulation, vascular function, and cellular homeostasis through interconnected pathophysiological mechanisms, increasing cardiometabolic disease risk. This randomized controlled trial examined whether 12 weeks of resistance-interval tra...

In-Context Molecular Property Prediction with LLMs: A Blinding Study on Memorization and Knowledge Conflicts

Abstract The capabilities of large language models (LLMs) have expanded beyond natural language processing to scientific prediction tasks, including molecular property prediction. However, their effectiveness in in-context learning remains ambiguous, particularly given the potent...

Relating transcriptomics to protein abundance reveals self‐driven versus interactor‐driven proteins

Statistically modeling the interdependence between transcriptomics and protein abundances remains a persistent challenge in bioinformatics research. Transcriptomic data and proteomic abundances typically display a moderate Pearson's correlation of about 0.5, while in tumor condit...

Proteomic profile of the dentine pellicle modified with plant polyphenols and fluoride

Abstract Objectives Despite its protective role, the dentine pellicle has rarely been studied, therefore we aimed to map out the proteomic profile of in vitro dentine pellicles before and after modification. Materials and methods A total of 135 human dentine specimens were prepar...

Parvovirus B19 infections in paediatric sickle cell disease patients: Genotype and hydroxyurea treatment influence disease severity

Summary In patients with sickle cell disease (SCD), parvovirus B19 infection (B19V) leads to acute anaemia (aplastic crisis), but may also be associated with other serious complications. We retrospectively analysed clinical data from paediatric SCD patients with B19V infections b...

Post-traumatic stress disorder following intensive care for COVID-19: a single-center retrospective follow-up study

Abstract Background Severe COVID-19 frequently required prolonged intensive care, including mechanical ventilation or extracorporeal membrane oxygenation (ECMO). Survivors of such critical illness may develop post-traumatic stress disorder (PTSD). Methods We conducted a single-ce...

Employer attractiveness of new businesses: a study of compensatory patterns in job applicants' intentions to apply

Purpose The study investigates how new businesses can strengthen their employer attractiveness at early stages, despite the risks associated with employment in such ventures. Specifically, it examines whether employer-related attributes in startup-like job ads are associated with...

Hydration Asymmetry and Solvent-Mediated Charge Balancing in Microporous Carbons: An NMR Study of Aqueous and Organic Electrosorption

Abstract Aqueous electrolytes are attracting increasing interest in supercapacitor applications due to their high sustainability and ionic conductivity relative to conventional organic systems. However, the distinct solvation properties of water and their impact on (electro)sorpt...

Effect of Poly[oligo(ethylene glycol) methyl ether methacrylate] (POEGMA) Side-Chain Length on the Antimicrobial Activity of Tobramycin-POEGMA Conjugates against Pseudomonas aeruginosa

Abstract Polymer conjugation of cationic antibiotics has emerged as a promising strategy to improve their pharmacological properties and enhance their performance in biofilm-associated infections. Herein, we investigate the effect of poly[oligo(ethylene glycol) methyl ether metha...

Understanding the Topology of Simple Coordination Structures in Nonmolecular Solids – A Course on Symmetry and Catenation of Polyhedra

Abstract We present a course explaining structural features found in inorganic ion crystals aiming to give an outline to lecturers for a stepwise introduction to specific structural phenomena. It deals with the symmetry of polyhedra and its modification starting from isolated one...

Organ and tumor dosimetry of [161Tb]Tb-PSMA-617 radioligand therapy in patients with mCRPC

Abstract Purpose Terbium-161 ( 161 Tb) has emerged as a promising radionuclide for radioligand therapy (RLT) due to its emission of Auger and conversion electrons, which may support therapeutic efficacy through increased local energy deposition. Despite growing research efforts a...