Royal Derby Hospital

Survival and Extent of Breast Surgery in Patients with Complete Response After Neoadjuvant Therapy: A Retrospective Analysis from the EUSOMA Database

ABSTRACTBackground: The optimal management of breast cancer (BC) patients with pathological complete response (pCR) following neoadjuvant therapy (NAT) remains debated. We performed a retrospective analysis to evaluate whether the extent of surgery influences survival outcomes in...

Consensus guidelines in the management of paediatric flexible flatfoot

Aims: The assessment and management of flexible flatfoot in children is inconsistent, reflecting a limited and heterogeneous evidence base. This study aimed to develop a British Society for Children's Orthopaedic Surgery (BSCOS)-led consensus guideline for the multidisciplinary a...

The effect of metabolic syndrome on bone mineral density in men and women: a systematic review & meta-analysis

Metabolic syndrome (MetS) is associated with alterations in body composition and metabolic health, however its impact on bone mineral density (BMD) remains unclear, with potential sex- and site-specific differences. We systematically searched PubMed, Scopus, MEDLINE and Google Sc...

An international position statement on practical approaches for inpatient continuous glucose monitoring, insulin pumps and automated insulin delivery systems in adults

There is an urgent and unmet need for a practical clinical guideline addressing the use of continuous glucose monitoring (CGM), insulin pumps and automated insulin delivery (AID) systems in hospital settings. The goal with this position statement is to facilitate effective and sa...

An International Position Statement on Practical Approaches for Inpatient Continuous Glucose Monitoring, Insulin Pumps, and Automated Insulin Delivery Systems in Adults

There is an urgent and unmet need for a practical clinical guideline addressing the use of continuous glucose monitoring (CGM), insulin pumps, and automated insulin delivery (AID) systems in hospital settings. The goal with this position statement is to facilitate effective and s...

Leucine-Enriched Essential Amino Acids in Clinical Practice: A Narrative Review

Muscle wasting driven by aging, chronic disease, or intensive exercise undermines mobility, metabolic health, and survival—yet the people who lose the most muscle are often those least able to eat more protein. Leucine-enriched essential amino acid (LEAA) mixtures combine a leuci...