Riyadh Armed Forces Hospital

Mesenchymal stem cells modulate pancreatic and splenic inflammation through PI3K/AKT/mTOR and TGF-β signalling in diabetic rats

Bone marrow-derived mesenchymal stem cells (MSC) can attenuate diabetic organ damage through immunomodulatory and paracrine mechanisms, yet the specific signalling pathways engaged in the pancreas and spleen remain poorly characterized. This study investigated the effects of a si...

Progress in Anti-Obesity Drug Development: A Pharmacodynamics Perspective

Background/Objectives: Obesity is a chronic, multifactorial condition driven by complex neuroendocrine and metabolic pathways that limit the long-term success of lifestyle interventions. Pharmacotherapy has advanced from early monoaminergic agents to incretin-based and multi-rece...

From Antimicrobial Biomaterials to Infection-Resilient Interfaces: Engineering the Host, Microbe, and Material Interface Against Drug-Resistant Biofilms

Drug-resistant biofilm infections remain a major challenge for medical devices and implants. Biofilm formation can reduce antimicrobial effectiveness through physiological heterogeneity, tolerance, persistence, and interactions with the host and biomaterial surface. Antimicrobial...

Impact of Smokeless Tobacco on Semen Quality: A Systematic Review and Meta‐Analysis

ABSTRACT Background Smokeless tobacco products are widely regarded as a safer alternative to smoking. However, a growing body of evidence points to harmful effects on male reproductive health. The aim of this systematic review and meta‐analysis was to assess the association betwe...

Burnout and resilience among healthcare nurses in Saudi Arabia: a cross-sectional study with exploratory multiclass classification approach

Burnout is a significant occupational and psychological concern among nurses. However, there is an evidence gap in research considering the dimensions of burnout and resilience in healthcare settings where the nursing workforce is predominantly expatriate. Therefore, this study a...

Perceptions of micro-learning modules on knowledge retention and clinical decision-making among physiotherapists: a cross-sectional study

Micro-learning has emerged as an innovative strategy for professional development in healthcare. Although its effectiveness has been demonstrated in various health professions, physiotherapists’ perceptions of its impact on knowledge retention and clinical decision-making remain...

Exploring Factors Influencing Vaccine Uptake From the Perspective of Physicians and Public: A Mixed Method Study

ABSTRACT Background Immunisation is recognized worldwide as one of the key strategies for extending life expectancy and improving health outcomes. Developing a national policy that improves the vaccination rate against diseases requires the barriers and facilitators to be identif...

Comparative effectiveness of biologic therapies for preventing asthma exacerbations in severe asthma: a systematic review and network meta-analysis

The comparative effectiveness of biologic therapies for preventing exacerbations in severe asthma remains uncertain because no eligible direct head-to-head randomized comparisons were identified. We compared six biologic therapies using a network meta-analysis (NMA). This systema...

Vitamin D deficiency among adults screened for orthodontic treatment in Saudi Arabia: prevalence and implications for trial recruitment

Vitamin D deficiency remains highly prevalent in the Middle East and may influence both oral-health research planning and orthodontic trial feasibility. This study estimated vitamin D deficiency prevalence in adults screened for orthodontic treatment in Saudi Arabia and quantifie...