Riga Stradiņš University

Depressive symptoms and fatigue are independently associated with myasthenia gravis-specific quality of life beyond neurological severity: a cross-sectional study

Neurological examination and myasthenia gravis (MG)-specific functional scales may not fully capture the psychological and fatigue-related burden of MG. This cross-sectional registry-based study included 75 adults with MG. Depressive and anxiety symptoms were assessed using the P...

Lysine-Based Amphiphiles with Pyrrole, Furan and Thiophene Linkers

The development of efficient cationic amphiphiles remains an important area in the design of nonviral systems for nucleic acid delivery. In this study, we report the synthesis of three lysine-containing lipid-like amphiphiles incorporating pyrrole, furan, and thiophene as five-me...

Industrial Symbiosis Readiness in the Western Balkans: Insights from Swedish and Latvian Experience for Albania

Industrial symbiosis (IS) is increasingly considered a practical pathway for advancing the circular economy, improving resource efficiency, and supporting sustainable industrial development. While IS has been widely discussed and applied in several European Union contexts, its de...

Suspected Type II Kounis Syndrome with Coronary Dissection Extending from the Distal Left Main into the Proximal Left Anterior Descending Artery After Wasp Sting Anaphylaxis: A Case Report

Kounis syndrome is an acute coronary syndrome occurring in temporal association with an allergic or anaphylactic reaction. Recognition may be particularly challenging in patients with established coronary artery disease, in whom hypersensitivity-mediated mechanisms may coexist wi...

Delayed Emergence Due to Prolonged Mivacurium Blockade in a Child with Markedly Reduced Butyrylcholinesterase Activity: A Case Report

Background: Delayed emergence after general anesthesia in pediatric patients is uncommon and requires prompt evaluation of pharmacological, metabolic, and neurological causes. Residual neuromuscular blockade remains an important reversible cause, particularly when short acting ne...

Salivary microbiome responses to chlorhexidine and Coriandrum sativum essential oil mouthwashes in patients with periodontitis in a randomized 2-week clinical trial

To compare the short-term salivary microbiome effects of a Coriandrum sativum essential oil (CSEO) mouthwash, chlorhexidine (CHX) as a benchmark comparator, and water in patients with periodontitis. In this randomized three-arm trial, participants with periodontitis rinsed twice...

Hereditary and Non-hereditary Cerebellar Ataxias in Latvia: Six Years of Experience at the National Reference Centre (ERN-RND Affiliated Partner)

Cerebellar ataxias are rare but disabling disorders, with marked regional differences in genetic subtypes. Data from Eastern Europe, especially the Baltic region, remain scarce. To describe the aetiological spectrum and diagnostic challenges of cerebellar ataxia in Latvia over a...

Electronic appendix A to "Mineralogical and geochemical characteristics and the genesis of the Paleoproterozoic Staicele and Gārsene Iron Ore Deposits of Latvia"

Electronic appendix A to "Mineralogical and geochemical characteristics and the genesis of the Paleoproterozoic Staicele and Gārsene Iron Ore Deposits of Latvia"; Vorobjovs, D., Stinkulis, Ģ., Bērtiņš, M., Vīksna, A., Meija, R., Brangule, A. Bulletin of the Geological Society of...

Electronic appendix A to "Mineralogical and geochemical characteristics and the genesis of the Paleoproterozoic Staicele and Gārsene Iron Ore Deposits of Latvia"

Electronic appendix A to "Mineralogical and geochemical characteristics and the genesis of the Paleoproterozoic Staicele and Gārsene Iron Ore Deposits of Latvia"; Vorobjovs, D., Stinkulis, Ģ., Bērtiņš, M., Vīksna, A., Meija, R., Brangule, A. Bulletin of the Geological Society of...

"I Can't Sing, I Can't Draw, I Can't Dance": Ascribed Inability and the Problem of Reversibility in Arts Education

“Ascribed inability” is proposed to describe situations in which an authorised evaluator’s judgement that a child lacks an artistic ability is internalised and may shape participation long after the underlying ability has ceased to be assessed. This conceptual article integrates...

Integrating academic and physical activities: Effects of camp-based learning on self-efficacy, resilience, and academic achievement

Background Innovative approaches in higher education highlight the importance of evaluating learning environments that integrate academic and physical activities to enhance students’ self-efficacy, resilience, and academic achievement. This study examined the effects of a camp-ba...

Gender-Based Discrimination and Its Associations with Mental Wellbeing, Self-Efficacy and Career Choice Among Medical Students in Latvia: A Cross-Sectional Study

Gender-based discrimination in medical education remains a critical yet overlooked issue that may adversely affect the mental health and professional development of future physicians. This study investigated the prevalence of such experiences and their association with mental wel...

Extensive Cochlear Otosclerosis: CT-MRI Correlation and the Diagnostic Value of Contrast Enhancement

Otosclerosis is a chronic disorder of the otic capsule. It is characterized by abnormal bone remodeling, which may extend beyond the fenestral region and involve the cochlea and other structures of the bony labyrinth. There are two main types of otosclerosis—retrofenestral (cochl...

No-Code and Low-Code Artificial Intelligence in Healthcare Imaging: A Scoping Review

Introduction and aims The aim of this review was to evaluate applications, methodological characteristics, limitations and future directions of no-code, low-code and automated machine learning (LCNC/AutoML) approaches in healthcare imaging. Methods PubMed, Web of Science, and Goo...

Exploring Healthcare Students’ Perspectives on Physical Activity: A Qualitative Study of Habits, Barriers and Facilitators, Academic Self-Efficacy, and Their Role as Future Health Promoters

PA is an important determinant of health and well-being; however, many university students, including healthcare students, do not achieve recommended activity levels despite their future role in health promotion. This study aimed to explore healthcare students’ perspectives on ph...

Myalgic encephalomyelitis/chronic fatigue syndrome and overlapping post-acute infection syndromes: international expert consensus framework for diagnostic standardization

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) lacks validated objective diagnostic criteria, leading to delayed diagnosis and inconsistent management. We aimed to establish an international expert consensus framework integrating measurable, risk-stratified assessmen...

Force production with a subset of fingers: two aspects of unintentional finger involvement

We explored the relations between unintentional finger force production (enslaving) and multi-finger force-stabilizing synergies using the framework of the uncontrolled manifold (UCM) hypothesis. In particular, we formulated three mutually exclusive hypotheses on the relations be...

Enzyme-Detergent and Detergent-Detergent Protocols for Human Urethra Decellularization: A Histological and Ultrastructural Study

Abstract Background and Objectives Decellularization of the human urethra produces extracellular matrix (ECM) bioscaffolds with strong potential for reconstructive urology, yet no standardized protocols exist for either cell removal or scaffold characterization. Histological asse...

Awareness of Menopause and Health Risks Among Reproductive-Age Women in Latvia

Background/Objectives: The menopausal transition is a period of increasing cardiometabolic risk and a window for prevention, yet preparation is often delayed until symptoms appear. Latvia has a high cardiovascular mortality burden, but population-specific menopause-awareness data...

Clinical and Immunological Associations of Plasma Platelet-Activating Factor in Chronic Spontaneous Urticaria

Background/Objectives: Chronic spontaneous urticaria (CSU) is a heterogeneous immune-mediated condition involving multiple inflammatory pathways. The clinical utility of platelet-activating factor (PAF) as a biomarker in CSU remains insufficiently defined. This study aimed to eva...