Rice University

Individualizing Informed Consent: For Whom, and How Far?

In 2018, the U.S. federal guidelines were updated to require the reasonable person standard during informed consent in research settings (Khatiwada et al. 2026). According to the standard, research...

Raman Enhancement of Molecules Sandwiched between van der Waals Materials

Abstract Raman enhancement has been widely observed for molecules adsorbed on van der Waals (vdW) materials including graphene, MoS2, hexagonal boron nitride, and transition-metal dichalcogenides. This enhancement is often dominated by a chemical mechanism. However, how the Raman...

Transforming Cadmium in Paddy Soils into a Catalytic Driver for Chlorantraniliprole Degradation: Implications for an Integrated Strategy for Tackling Heavy Metal–Organic Cocontamination

Abstract Developing remediation strategies for heavy metal–organic cocontamination in paddy soils is imperative to ensure food safety. Current soil remediation strategies typically address these pollutant classes separately, often creating trade-offs in which mitigating one class...

Hippocampal contributions to reading processes

Abstract The cortical substrates of typical reading have been extensively investigated. However, the functional contributions of subcortical regions to reading remain poorly understood and are largely absent from current neuroanatomical models. In the present fMRI study, we analy...

Fractionation of alkali feldspar: on making high Ga/Al granite

The classification of granites is marked by inconsistencies. For example, the widespread classification of granites into A-type was initially based on associations with extension-related tectonic environments while the I- and S-type classifications were based on inferred source r...

Gastrointestinal Bleeding Is Associated with Worse In-Hospital Outcomes in Patients with ST-Segment Elevation Myocardial Infarction: An Analysis of the National Inpatient Sample

Background/Objectives: Patients with ST-segment elevation myocardial infarction (STEMI) may develop gastrointestinal (GI) bleeding. We aimed to assess the impact of GI bleeding on in-hospital outcomes in patients with STEMI. Methods: This retrospective study was performed using t...

Large language model-enabled automated data extraction for concrete materials informatics

The promise of data-driven materials discovery remains constrained by the scarcity of large, high-quality, and accessible experimental datasets. Here, we introduce a generalizable large language model (LLM)-powered pipeline for automated extraction and structuring of materials da...

Can a public information campaign increase trust in American elections?

Confidence in the conduct and results of American elections has declined and polarized along party lines in recent years. Can a nonpartisan public information campaign featuring election officials enhance trust in elections when delivered to skeptical voters during a contentious...

Learning induces activation-mechanism–dependent neural plasticity in an intracortical microstimulation task

Electrical microstimulation provides high-resolution control of neural circuits for causal studies and restoration of impaired functions, yet how responses to artificial activation evolve with learning remains unclear. Here, we deploy a detection task and pair ultraflexible elect...

Sensitivity-Driven Adaptive Surrogate Modeling for Simulation and Optimization of Dynamical Systems

Abstract. This paper develops a surrogate model refinement approach for the simulation of dynamical systems and the solution of optimization problems governed by dynamical systems in which surrogates replace expensive-to-compute state- and control-dependent component functions in...

Alcohol Use Severity Among Hispanic Emerging Adult College Students: Examining Acculturation Stress, Self-Esteem, and Resilience in a Stress and Coping Framework

Research on acculturation stress and its effects on alcohol-related outcomes among Hispanics has been the subject of many studies. However, these studies are limited because they generally use a single measure of acculturation stress to account for this complex construct, and mos...

Peskine Sixfolds and Debarre–Voisin Fourfolds With Associated Cubic Fourfolds

ABSTRACT We develop the notion of Peskine sixfolds with associated K3 surfaces and cubic fourfolds and work out numerical conditions for when these associations occur. In discriminant 24, the first family for which there is an associated cubic fourfold, we identify the cubic expl...

The Honor of a Leader: Examining the Content of Honor-Congruent Leadership Prototypes

Across three studies, we investigated how honor norms are associated with leadership prototypes. An archival, national-level study and an individual-level correlational study both linked honor norms to tough, reputation-conscious leadership and preferences for male leaders. A pre...

Reversing the Vigilance Decrement: Effects of a Late Modality Switch on Detection Performance

When people monitor rare signals for sustained periods, detection performance declines over time (vigilance decrement). In applied settings this decline can lead to missed critical signals. Prior research examined whether changing display modalities would improve detection after...

Genomic predisposition is associated with the direction of sex chromosome evolution

Sex chromosome evolution is among the most dynamic genomic innovations in vertebrates, yet why some lineages evolve XY while others evolve ZW remains unclear. Using chromosome-level genomes from 19 geckos, we found that gecko sex chromosomes originated independently from 16 ances...

Cheminformatic identification of small molecules targeting acute myeloid leukemia

Abstract Acute myeloid leukemia (AML) is an aggressive hematological malignancy with poor prognosis and high relapse rates when treated with cytotoxic chemotherapeutics. Previously, we identified a family of small molecules that modulate mitochondrial function, referred to as PS1...

Adaptive model-guided protein evolution with sparse data optimizes compact eukaryotic genome editors

Efficient protein engineering is constrained by vast sequence space and limited experimental throughput, particularly for protein families that lack large mutational datasets. Here we combine Fanzor2 (Fz2) ortholog discovery, ωRNA scaffold engineering and EvoMax, a model-guided p...

Identifying active surfaces for C2 decomposition relevant to the FC-CVD CNT synthesis process

Selecting for high quality carbon nanotube (CNT) growth during the floating catalyst vapour deposition (FC-CVD) synthesis process remains a challenge due to the coupling of physical and chemical phenomena inside the reactor. While there is evidence implicating C2 species as the p...

Beyond Burnout: Determinants and Consequences of Sustainable Nonprofit Leadership

Much of the scholarship on leadership wellbeing and effectiveness has focused on ways to avoid burnout, rather than explaining how leaders actively sustain wellbeing and effectiveness over time. This paper integrates multiple theoretical frames using an exploratory, sequential mi...

Artificial intelligence-enabled analysis of electron micrographs to assess mitochondrial morphology in triple-negative breast cancer

Advancements in transmission electron microscopy (TEM) have enabled in-depth studies of biological specimens, offering new avenues to large-scale imaging experiments with subcellular resolution. Mitochondrial morphology is of growing interest in cancer biology due to its crucial...