Research Organization of Information and Systems

A Spatio‐Temporal Neural Kernel Function Model for Earthquake Clustering: Bridging ETAS and Neural Point Processes

Abstract Modeling earthquake clustering in space and time is central to understanding seismicity patterns and improving forecasting. The Epidemic‐Type Aftershock Sequence (ETAS) model, grounded in the Hawkes process, has long been the standard approach for describing aftershock t...

Cohesin acts as a transcriptional gatekeeper by restraining pause–release to promote processive elongation

Abstract Cohesin organizes 3D chromatin architecture, including promoter–enhancer loops, yet its loss has surprisingly modest effects on steady-state gene expression. We address this paradox by demonstrating that cohesin acts at different stages of transcription. First, it promot...