Pusan National University

Salivary Microbiota and Network Alterations in Oral Lichen Planus with Candida Compared to Healthy Controls

Background: Oral lichen planus (OLP) is a chronic immune-mediated mucosal disorder frequently accompanied by Candida colonization. However, the polymicrobial interactions and network alterations underlying this association remain poorly understood. This study aimed to characteriz...

Resorufin‐Catalyzed PhotoATRP Under Red Light

ABSTRACT The sodium salt of resorufin (RSF), an inexpensive, water‐soluble, commercially available phenoxazinone dye, serves as an efficient photocatalyst for low‐copper dual‐catalysis PhotoATRP across the visible spectrum. RSF loadings as low as 1 ppm catalyzed PhotoATRP of acry...

Uncertainty-driven connectedness in global gold-mining equities: A Time–Frequency and quantile approach

This study examines how connectedness among global gold-mining equities varies across market regimes, investment horizons, and return states, and whether gold-specific uncertainty adds information beyond gold prices and broad market volatility. The sample comprises eleven gold-mi...

North Atlantic chlorophyll blooms modulate European hydroclimate and terrestrial productivity

Marine and terrestrial ecosystems are usually treated as separate components of the global carbon cycle, and whether variability in ocean biology reaches plant growth on land has remained unclear. Here we show that phytoplankton blooms in the high-latitude North Atlantic are link...

Opiranserin (VVZ-149): what’s new in analgesics

cannot be fully anticipated. The major clinical concern is that opiranserin cannot be added to disposable intravenous patient-controlled analgesia devices due to their limited volume. Repeated administration may accumulate its active metabolite, VVZ-368 (N-desmethyl-VVZ-149).

Carleson measures for weighted Bergman–Zygmund spaces

Abstract For $$0 0 < p < ∞ , $$\Psi :[0,\infty )\rightarrow (0,\infty )$$ Ψ : [ 0 , ∞ ) → ( 0 , ∞ ) and a finite positive Borel measure $$\mu $$ μ on the unit disc $$\mathbb {D}$$ D , the Lebesgue–Zygmund space $$L^p_{\mu ,\Psi }$$ L μ , Ψ p consists of all measurable functions f...

Management Regime and Wildfire Outcomes: Burn Severity and Post-Fire Recovery in a Korean National Park and a Pine-Dominated Managed Forest Burned Three Days Apart

Active management making forests more resistant to wildfire and more resilient afterwards is a widely held assumption that is rarely tested against comparable fires. In March 2023, two wildfires ignited three days and 54 km apart under the same synoptic weather in southern Korea,...

Mixed Potential Behavior in Thick Li‐Ion Battery Electrodes Under Fast Charging

For lithium‐ion batteries (LIBs) with high energy and power densities, the demand for fast charging with thick‐film electrodes is growing; however, fast charging can induce a nonuniform state of charge (SoC) within the electrodes. This work investigates the effects of nonuniform...

Current Guidelines for the Laboratory Detection and Interpretation of Lupus Anticoagulant

역 혈전성 질환이다.APS 진단에 필요한 검사 기준으로는 루푸스 항응고인자(lupus anticoagulant, LAC), 항카디오리핀 항체(anti-cardiolipin antibody, aCL), 항β2-당단백질 I 항체(anti-β2-glycoprotein I antibody, aβ2GPI)가 있으며, 이 중 LAC는 혈전 위험도와의 연관 성이 가장 강력하다[1, 2]."...

Natural Bioactive Compounds Targeting Obesity-Related Molecular Pathways: Mechanisms, Clinical Evidence, and Therapeutic Perspectives

Obesity is a major global health challenge associated with insulin resistance, hypertension, type 2 diabetes, and metabolic dysfunction-associated steatotic liver disease.Although pharmacotherapy and bariatric surgery can be effective, limitations related to cost, safety, accessi...

Comparative study on the clinical effectiveness of low-concentration cyclosporine eye drops in patients with dry eye disease

Purpose This study aimed to evaluate the efficacy and safety of low-concentration, nanoparticle-based cyclosporine eye drops (SCAI-001 0.01% and SCAI-001 0.02%) compared to those of the conventional Restasis ® (cyclosporine 0.05%) emulsion for dry eye disease (DED). Methods In th...

Orientation-dependent ballistic response of textured Mg alloy plates: From deformation mechanisms to macroscopic fracture

α -Mg alloys inherently exhibit pronounced plastic anisotropy owing to the limited slip systems of their hexagonal close-packed lattice; this anisotropy is amplified by the crystallographic texture developed during thermomechanical processing. Despite extensive studies on quasi-s...

Seroprevalence of Toxoplasma gondii among animal-associated workers and companion animals in South Korea

Abstract Toxoplasma gondii is a widely distributed zoonotic parasite at the human–animal interface. However, studies simultaneously evaluating animal-associated workers and companion animals remain limited in South Korea. This multi-regional cross-sectional study aimed to estimat...

Qualitative analysis of a health systems science (HSS) course incorporating early clinical exposure

Health systems science (HSS) is increasingly recognized as a core component of contemporary medical education. Although early clinical exposure (ECE) has been shown to enhance students’ understanding of clinical practice, evidence regarding its role in shaping HSS-related perspec...

Sociodemographic, Self-Efficacy, and Health-Related Factors According to the Stages of Change in Physical Activity and Dietary Management Among Patients with Metabolic Syndrome: A Secondary Analysis of a Cross-Sectional Study

Purpose: This study aimed to examine differences in sociodemographic characteristics, self-efficacy, and health-related factors across the stages of change for physical activity and dietary management among patients with metabolic syndrome (MetS). Methods: This secondary analysis...

The Traditional Medicine Gamisoyosan Mitigates IBS Symptoms by Regulating Inflammatory and Pain Mechanisms

Background Gamisoyosan (GSS) is a traditional herbal medicine composed of nine medicinal ingredients and has been widely used for the treatment of various diseases, including gastrointestinal disorders. However, its therapeutic effects on irritable bowel syndrome (IBS) and the un...

Muted orbital-scale monsoon variability over the Korean Peninsula

A recent study identified an east-west dipole pattern in Asian Summer Monsoon precipitation and in its oxygen-isotope composition variability in response to orbital forcing (Wen et al., 2024). The Korean Peninsula (KP) is situated near the nodal line of this dipole and should the...

2D nanomaterials for near infrared responsive photomedicine: a review

The continuously growing demand for efficient and non-invasive treatment has accelerated the development of near infrared (NIR) responsive phototherapy, a therapeutic modality that leverages the biological transparent window (700–1850 nm) to enable deeper tissue penetration compa...

Assessing 3D shape cognition using BVH-based hierarchical geometric disclosure

Assessing human 3D shape cognition in a controlled and quantifiable manner remains challenging, as existing approaches often rely on visual cues influenced by prior experience. We introduce a geometry-based experimental paradigm in which 3D objects are progressively disclosed usi...

scTrans-SVD: dual-view learning with a low-rank representation for label-limited cell type annotation in single-cell transcriptomics

Single-cell transcriptomic profiling reveals cellular heterogeneity, but reliable cell type labels are often available for only a subset of profiles. This setting motivates approaches that can use label-withheld training expression while retaining measured gene expression as a di...