Poznan University of Medical Sciences

RED-S IN ENDURANCE ATHLETES — SKELETAL CONSEQUENCES OF CHRONIC LOW ENERGY AVAILABILITY

Background. Relative Energy Deficiency in Sport (RED-S) is an increasingly recognized health problem among endurance athletes. The main mechanism leading to the development of RED-S is low energy availability (LEA), resulting from insufficient energy intake in relation to exercis...

The Transition of Youth With Diabetes From Pediatric to Adult Diabetes Care Services: A Consensus Report of the Joint Working Group of the International Society for Pediatric and Adolescent Diabetes (ISPAD), the European Association for the Study of Diabetes (EASD), and the American Diabetes Association (ADA)

Young adulthood is a period of significant and unique physiological, psychological, sexual, and social upheaval. Related challenges can have an impact on effective diabetes self-management, with high rates of unplanned health care use recorded for many, and consequent increases i...

Autologous Tissue Grafts for Chin Augmentation with or Without Genioplasty: A Systematic Review

Objective: This systematic review evaluated the clinical application of autologous tissue grafts for chin augmentation performed with or without genioplasty. The primary outcomes included clinical and aesthetic improvement, graft stability and integration, resorption, complicatio...

Mesenteric Panniculitis and the Gut–Mesentery–Metabolic Axis: A Hypothesis-Generating Narrative Review

Mesenteric panniculitis (MP) is an uncommon inflammatory disorder of mesenteric adipose tissue. Its pathophysiology remains unclear. Gut dysbiosis, intestinal barrier dysfunction, metabolic endotoxemia, glycemic variability (GV), and vascular dysfunction have been implicated in i...

Surgical Ablation for Atrial Fibrillation During Minimally Invasive Mitral Valve Surgery: Risk Dependencies and Long-Term Survival

Objective: Atrial fibrillation (AF) is a common finding among patients with mitral valve disease, with a growing body of evidence showing survival benefits associated with surgical ablation (SA). However, a lack of data persists regarding the safety and survival after SA concomit...

Evaluating undergraduate palliative care education: changes in nursing students’ attitudes toward end-of-life care following a curriculum-based programme

Abstract Aim To evaluate the preparedness of undergraduate nursing students for the provision of end-of-life care and to identify their self-perceived educational needs in this domain. Background The adequate preparation of nursing students for end-of-life care delivery remains a...

Does size matter? A secondary analysis of the effect of region-of-interest size on muscle echotexture features of the gastrocnemius medialis in stroke

The analysis of muscle echotexture using ultrasound imaging is attracting increasing interest for assessing muscle tissue across different health conditions. However, variability in the size of the region of interest (ROI) can affect echotexture assessment. This study examines ho...

Relaxation Polyamorphism of Rosuvastatin and Physicochemical Characterisation of a Rosuvastatin–Carvedilol Co-Amorphous System

Objective: In this study, the solid-state properties of two amorphous forms of rosuvastatin calcium (ROS) and co-amorphous systems of rosuvastatin with carvedilol (CAR) were investigated. Methods: The studied systems were investigated using TGA, DSC, TMDSC, PXRD, SAXS, SSNMR, and...

From ANCA-mediated vascular injury to coronary microvascular and myocardial involvement in granulomatosis with polyangiitis: an immunocardiology perspective

Granulomatosis with polyangiitis (GPA) is a prototypical antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis characterized by necrotizing inflammation of small- and medium-sized vessels with granulomatous features. Although advances in immunosuppressive therapy have...

Associations of IL-2, IL-6 and IL-10 Gene Polymorphisms with Biochemical Parameters and Calcineurin Inhibitor Dosing in Kidney Transplant Recipients

Background/Objectives: Kidney graft dysfunction remains a major challenge limiting long-term transplant survival despite advances in immunosuppressive therapy. Cytokine signaling pathways have been implicated in the regulation of alloimmune responses and chronic inflammation, but...

Recommendations of Multiple Sclerosis and Neuroimmunology Section of the Polish Neurological Society and the Polish Society of Gynecologists and Obstetricians for family planning and pregnancy management in women with multiple sclerosis: an update

INTRODUCTION: Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the Central Nervous System that most commonly affects females of reproductive age. Therefore, the issue of family planning is relevant in this population, especially in the context of starting a...

Geriatric nutritional risk index as a potential prognostic indicator in pancreatic cancer: evidence from a systematic review and meta-analysis

Malnutrition is highly prevalent among patients with pancreatic cancer and has a substantial impact on prognosis, treatment tolerability, and quality of life. However, the prognostic significance of the Geriatric Nutritional Risk Index (GNRI), a simple and objective tool for asse...

Severe visual impairment as a complication of autism spectrum disorder

Purpose To report the irreversible vision loss caused by optic neuropathy in a course of a vitamin A deficiency. Methods Electroretinography (ERG) and pattern visual evoked potentials (PVEP) were used to establish a diagnosis, and to monitor the treatment in a child suffering fro...

Efficacy and tolerability of venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukemia – real-world analysis of Polish adult leukemia study group

We collected clinical data on 363 patients with relapsed/refractory chronic lymphocytic leukemia (RR-CLL) treated with venetoclax-rituximab (VR) in a real-world setting. The median age was 69.5 years (range, 32.5–91.6 years), and the median number of prior lines of therapy was 2...

No Conscious Units: A Relational Theory of Consciousness and the Dissolution of the AI Consciousness Question

This paper challenges a largely unexamined assumption of contemporary consciousness studies: that consciousness is an intrinsic property of objects. Drawing on the Madhyamaka analysis of emptiness (sunyata) and dependent origination, and on independent convergences in relational...

Preoperative Plasma Cell-Free DNA Integrity Index in Clear Cell Renal Cell Carcinoma: An Exploratory Case–Control Study

Background/Objectives: Evaluation of renal tumour masses relies on conventional imaging, which cannot reliably characterise the histopathological type, and no validated blood-based diagnostic marker is available for renal cell carcinoma. The cfDNA integrity index, the ratio of lo...

Unmasking Behçet’s disease in the European population: a case series report

Behçet’s disease (BD) is rare in European populations. Because clinical and immunological characteristics may differ between Caucasians and Middle Eastern patients, we analyzed BD patients from the Polish population. Data from eight patients with BD treated at a rheumatology clin...

Sub‐ UV Trichoscopy for the Assessment of Acute and Subacute Form of Alopecia Areata

The authors declare no conflicts of interest. The data that support the findings of this study are available from the corresponding author upon reasonable request.

The evolution of thyroid cancer diagnostics: Historical milestones and their impact on contemporary clinical practice

Thyroid cancer represents the most prevalent malignancy of the endocrine system, with its incidence exhibiting a significant rise in recent years. Diagnostic methods have undergone profound evolution over the past century, progressing from basic clinical examination to a sophisti...

The impact of FTO and ADRB3 gene variants, physical activity and proper diet on weight gain and perinatal outcomes in pregnant women with obesity

This study aimed to evaluate the effects of FTO (rs9939609) and ADRB3 (rs4994) gene variants, dietary intervention, and physical activity on gestational weight gain and perinatal outcomes in women with obesity and early gestational diabetes (GDM). In this prospective study, 115 p...