Poznan University of Medical Sciences

Septic arthritis attributed to a spider bite — a case report and review of the literature

Individuals who travel to tropical or subtropical areas are exposed to various infectious, environ-mental, and climatic risk factors, as well as traffic accidents, security problems, natural disasters, and direct contact with potentially dangerous plants or animals. Accidental bi...

The Prognostic Role of HPV Status Based on the Analysis of Outcomes of Combined Treatment of Oral Cavity and Oropharyngeal Cancers

Background and Objectives: The aim of the paper is to assess the impact of HPV DNA on the survival and cure rates of patients with newly diagnosed head and neck cancers. Materials and Methods: The study group consisted of 51 patients with squamous cell carcinoma of the oral cavit...

Anti-inflammatory diet as an element supporting the treatment of selected gynecological diseases — literature review

Low-grade chronic inflammation plays an important role in the pathogenesis of many gynecological diseases, including polycystic ovary syndrome (PCOS), uterine fibroids, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD) and endometriosis. The aim of this paper wa...

Beyond Histocompatibility: Donor Tissue Immune States and Their Role in Heart Transplantation

Heart transplantation transfers not only donor alloantigens and functional myocardium but also a pre-existing tissue environment shaped by resident immune, vascular, stromal, and parenchymal populations. This review examines the hypothesis that the biological state of donor tissu...

Multimodal Hyperspectroscopy with LuViva® for Detection of CIN2+ in Women Referred for Colposcopy: A Prospective Diagnostic Accuracy Study

Objectives: This study aims to evaluate the diagnostic performance of multimodal hyperspectral spectroscopy (MHS) using the LuViva® Advanced Cervical Scan for the detection of cervical intraepithelial neoplasia grade 2 or worse (CIN2+) in women referred for further cervical asses...

Gut Microbiota and Nutritional Aspects in Pancreatic Diseases: A Narrative Review

Pancreatic diseases, including acute pancreatitis (AP) and chronic pancreatitis (CP), pancreatogenic diabetes mellitus (T3cDM), autoimmune pancreatitis (AIP), and pancreatic cancer (PDAC), are associated with metabolic, inflammatory, and nutritional disturbances. Increasing evide...

Using multi-trait polygenic scores to predict lithium responsiveness in patients with bipolar disorder

Background The predictive power of polygenic scores (PGSs) for lithium treatment response in bipolar disorder remains limited. Aims To enhance the prediction of lithium responsiveness by developing a multi-trait PGS (mt-PGS) combining genetic information from multiple phenotypes...

Deep Proteomic Profiling of Honeybee Venom Using Ion Mobility-Resolved 4D Proteomics – A Pilot Study

This dataset contains the raw data underlying the results presented in the associated manuscript (Deep Proteomic Profiling of Honeybee Venom Using Ion Mobility-Resolved 4D Proteomics – A Pilot Study). The files include unprocessed measurements collected during the study and are p...

The Effects of the Rearing System, Genotype at the RYR1 Locus and Sex of Fattening Pigs on Selected Biochemical Blood Parameters and Concentrations of Cortisol and β-Endorphin

There has been a growing interest in alternative rearing systems, including free-range rearing. This is particularly important in the case of indigenous pig breeds, which are prized for the high quality of their meat and traditional products, and whose importance in the productio...

When analgesics are not enough for postpartum perineal pain—a scoping review of the non-pharmacological, conservative therapies

Postpartum perineal pain affects up to 90% of women, with 37% reporting moderate to severe pain. Assisted delivery, episiotomy, and lacerations increase pain and medication use. Management includes pharmacological treatments like paracetamol, opioids, and non-steroidal anti-infla...

Assessment of Antioxidant Potential and Polyphenol and Mineral Content in Selected Green Vegetables Subjected to Sous Vide Cooking and Steaming

Green vegetables are rich sources of bioactive substances, including polyphenols and minerals, whose content and biological activity change during various technological processes. The aim of this study was to evaluate the effect of sous vide cooking at three different temperature...

The Role of Telomerase in Cellular Stress Response—Therapeutic Potential of Telomerase Inhibitors

Cancer remains one of the most complex diseases and a major global problem. Current therapeutic strategies often fail because of severe side effects and insufficient selectivity. Thus, there is a need to identify novel, specific targets and personalized therapeutic approaches. Te...

Trendy, but Are They Safe? Current Popular Diets and Their Use in Inflammatory Bowel Diseases: Narrative Review

Inflammatory bowel disease (IBD) arises from the interplay between genetic susceptibility, immune dysregulation, microbiota, and environmental exposures, with diet potentially contributing to both pathogenesis and management. Patients frequently modify their diet independently, o...

The impact of preoperative therapy with GLP-1 receptor agonists on weight loss and metabolic effects after bariatric surgeries – single-center preliminary study

Glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonists) have become an integral component of obesity management. Although these agents effectively induce preoperative weight loss, their influence on postoperative outcomes following bariatric surgery remains uncertain....

Tobacco and nicotine product use patterns among young healthcare professionals in Poland: findings from the qualitative component of the NIKO Study

While healthcare professionals (HCPs) are in many ways the best-positioned promoters of smoking cessation, many of them use tobacco and nicotine products (TNPs), which can undermine their credibility. In this paper, we report a qualitative study undertaken to assess TNPs’ use pat...

Effect of physical activity on placental glucose transporter expression in women with early gestational diabetes (eGDM): a secondary analysis of the randomised clinical trial

OBJECTIVES: Glucose is the primary energy substrate for the developing foetus, and placental glucose transport is a key element of pregnancy physiology. In early gestational diabetes mellitus, metabolic alterations may disrupt the expression of glucose transporters (GLUTs). This...

Genetic and Molecular Determinants of Cancer Therapy-Related Cardiovascular Toxicity

Cancer therapy-related cardiovascular toxicity (CTR-CVT) is an umbrella term for myocardial, vascular, electrical, and inflammatory complications of cytotoxic, targeted, immune, and radiation-based therapies. Cancer therapy-related cardiac dysfunction (CTRCD) is used here more na...

The influence of the geometry of the irradiated optical fibre on the Cherenkov radiation during small-field dosimetry using Exradin W2 scintillators

Abstract Stereotactic Body Radiation Therapy (SBRT) and Stereotactic Radiosurgery (SRS) pose significant dosimetric challenges due to their small field sizes and high fractional doses. Plastic scintillation detectors (PSDs) offer promising potential as non-reference dosimeters, o...

Smoking behaviours and attitudes among dental students in three European countries: a multicentre cross-sectional study

Tobacco use remains a major public health concern and a significant risk factor for systemic and oral diseases. Dental students, as future healthcare professionals, are expected to play an important role in tobacco control and smoking cessation. This multicentre study aimed to as...

Discordance between concern and guideline-defined gestational weight gain status: a multicentre cross-sectional study of pregnant women

Concern about gaining too much weight may not correspond to guideline-defined excessive gestational weight gain (GWG) and may instead reflect body-related experiences. We assessed concordance between concern and excessive GWG and associations of concern, weight-related body estee...