Plovdiv University

2-Propyl-1-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)pentan-1-one

A new hybrid molecule, combining the pharmacologically relevant scaffolds of valproic acid and trimetazidine, is reported. The target compound was synthesized via a rapid mechanochemical approach using a planetary ball mill, enabling the efficient coupling of the branched-chain v...

Energy-Efficient SIMD-Accelerated Expression Parsing: A Cross-Architectural Microarchitectural Analysis in Managed Environments

Mathematical expression evaluation is a critical component in high-performance software systems. Traditional state-dependent algorithms resist Single Instruction, Multiple Data vectorization, while managed runtime environments introduce Garbage Collection overhead. This paper pre...

Evaluation of Anthranilamide Derivatives on Learning and Memory Processes in Naïve Rats: In Silico Predictions and In Vivo Behavioral Profiling

Background: Anthranilamides have attracted increasing attention due to their antispasmodic and anti-inflammatory effects. The present study aimed to comparatively evaluate the effects of three previously synthesized anthranilamides, namely 2-chloro-N-(2-(phenethylcarbamoyl)phenyl...

Impact of IoT (BLE) and LTE on Fleet Efficiency: An Empirical Case Study of a Bulgarian Logistics Company

Background: Despite the widespread adoption of IoT and LTE technologies in logistics, empirical research quantifying the economic impact of preventing operational errors remains scarce. Methods: This paper presents a case study of a Bulgarian transport company with over 800 tract...

Stability for Switched Fractional Differential Equations with Random Switching Times

Stability analysis of switched nonlinear fractional differential equations is considered in this paper. The main characteristic of our problem is random switching times when the switching rule is activated. Here, the switching rule is independent of the state of the system, but i...

Finite-Observation Conditional Guarded Language Operators: Kannan Contractions Beyond Banach Contractivity

We introduce finite-observation conditional guarded language operators on the complete length-based ultrametric space of formal languages over a finite alphabet. A finite observation map selects a guarded branch according to the membership of prescribed test words. Although each...