Patan Academy of Health Sciences

Serum procalcitonin as an early marker associated with postoperative complications following liver resection: A prospective observational study

Postoperative complications (POC) following liver resection (LR) can significantly affect patient outcomes, and early predictors are crucial for timely intervention, particularly in resource-limited settings such as Bangladesh. In this prospective observational study conducted fr...

A reusable model of pangenome selection informs optimal surveillance strategies over vaccine introductions

Abstract Background The human pathogen Streptococcus pneumoniae is a major cause of disease, including pneumonia and meningitis. The introduction of Pneumococcal Conjugate Vaccines (PCVs) initially reduced the burden of disease through a reduction of colonisation by vaccine-targe...

Persistence of immune responses 5 years after vaccination with a single dose of typhoid conjugate vaccine (TCV) in Nepalese children

Background A single-dose typhoid conjugate vaccine (TCV) has been recommended in endemic settings. Here we report the 5-year immunogenicity results post a single dose of TCV in Nepal. Methods We conducted a participant- and observer-blinded randomised trial (RCT) in Lalitpur, Nep...

Knowledge and utilization of family planning and safe abortion services among married women of reproductive age in the Raute community of Nepal: A census-based cross-sectional study

Abstract Indigenous and nomadic communities worldwide face disproportionate and persistent barriers to reproductive health services, including family planning and safe abortion. The Raute of Nepal — one of the country’s last nomadic hunter-gatherer groups represent a uniquely mar...

Stochastic Scenario Modelling of Tobacco Taxation in Nepal: Evaluating 5–10 Year Pathways to Achieve a 75 Percent Tax Share

Tobacco consumption is a major public health and economic burden in Nepal, and taxation is a central policy tool for its reduction while increasing fiscal revenue. However, the most effective pathway to achieve the WHO-recommended 75 percent tax share under different reform timel...