Panzhihua University

Hybrid Graph Neural Network Ensemble with Stacked Meta-Learning for Laboratory-Conditioned Chromatographic Retention-Time Prediction

Abstract Accurate prediction of chromatographic retention time (RT) is valuable for compound identification in untargeted metabolomics and forensic toxicology, yet validation must account for repeated molecular structures, chemical-space coverage, and heterogeneous laboratory sou...

Nano-modified biochar mitigates toxicity from co-contamination with lead and microplastics in alfalfa by modulating photosynthesis, nitrogen assimilation, and antioxidant systems

Microplastics (MPs) and heavy metals are released into the environment and pose serious challenges to crop productivity and human health. The role of biochar and calcium oxide nanoparticle (CaO-NPs) modified (NBC) in mitigating MPs and lead (Pb 2+ ) toxicity has not yet been expl...

A convolutional autoencoder network based on multi-dimensional spatial feature reconstruction for anomaly detection of rotating machinery under complex operating conditions

Rotating machinery is critical equipment in industrial systems, and its operational status directly impacts production safety and equipment reliability. Due to complex operating conditions, continuous operation, and environmental disturbances, rotating machinery is prone to failu...

Dihydroartemisinin overcomes cisplatin resistance in bladder cancer via suppression of the PI3K/AKT/ABCB1 signaling Axis

Abstract Cisplatin resistance substantially limits the efficacy of bladder cancer chemotherapy, and effective strategies to overcome resistance remain insufficient. In this study, we demonstrate that dihydroartemisinin (DHA) restores cisplatin sensitivity in resistant bladder can...

A review on the application of the red mud-based adsorbents for industrial and municipal pollutants remediation

Red mud is the residue produced from the alumina manufacturing process, which is one of the largest volume industrial solid wastes worldwide. The large-scale annual accumulation of the red mud not only occupies valuable land resources but also leads to soil alkalization, which al...

Preparation of low-density polyethylene-based magnetic N/S carbon material for Cr(VI) removal

Low-density polyethylene (LDPE) is used to prepare the recyclable magnetic LDPE -based N/S-carbon material (WPC-NS) for Cr(VI) removal from wastewater. The Cr(VI) removal process under different removal conditions is deeply analyzed. The saturation magnetization of WPC-NS reaches...

LncRNA DLGAP1-AS2 promotes ESCC progression and indicates unfavorable prognosis via the miR-101-3p/EZH2 axis

LncRNAs are crucial regulators and biomarkers in various cancers. However, their expression and functions in esophageal squamous cell carcinoma (ESCC) remain largely unexplored. This study explored the clinial relevance and mechanisms of LncRNA DLGAP1-AS2 in ESCC. Utilizing the G...

Resveratrol attenuates tubular injury in diabetic kidney disease by suppressing the ferroptosis–ferritinophagy pathway

Abstract Background Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease, and renal oxidative stress (OS)–mediated tubular injury plays a critical role in its progression. Resveratrol (Res) possesses established antioxidative properties, yet its mechanistic...

Highly DispersedCuO/ZnO Nanocomposite Supported onMgO as Catalyst for the Purification of Trioxane: Transfer Hydrogenationof Formaldehyde Impurities to Methanol

Abstract In trioxane (TOX) production, unreacted formaldehyde (HCHO) readily forms a hard-to-separate ternary azeotrope with TOX and water, impairing purification efficiency and increasing energy demand. We report a green catalytic strategy that selectively converts azeotropic HC...