Østfold Hospital Trust

Low‐level light therapy for dry eye disease and meibomian gland dysfunction: A systematic review and meta‐analysis

Abstract A healthy tear film is vital for ocular surface integrity and relies on the coordinated function of the lacrimal glands, meibomian glands and conjunctival goblet cells. Dysfunction in any of these elements can lead to dry eye disease (DED). This systematic review and met...

Nicotinamide Riboside for Patients With Early-Stage Parkinson Disease

Importance Nicotinamide riboside, a nicotinamide adenine dinucleotide precursor, has been proposed as a potential disease-modifying therapy for Parkinson disease based on preclinical and early studies. Whether prolonged oral nicotinamide riboside improves clinical outcomes in Par...

Robust inference and correlates from genetic associations with personality

Personality traits describe stable differences in how people think, feel and behave, and how they interact with and experience their social and physical environments1,2. Many questions remain unanswered about associations between DNA and personality traits, such as their robustne...

Pyrocarbon Hemiarthroplasty Via Lateral Approach for the Treatment of PIP Osteoarthritis

Hemiarthroplasty of the proximal interphalangeal (PIP) joint using a pyrocarbon implant was initially described for the salvage of nonreconstructable fractures with loss of 1 joint surface. Later, this method was used to treat osteoarthritis. PIP hemiarthroplasty is less invasive...

In vivo quantification of polyethylene wear in total ankle arthroplasty

Aims In vivo assessment of polyethylene (PE) wear in total ankle arthroplasty (TAA) relies on approximation using 2D metal interspace height (2D-MIH) loss on weightbearing radiographs. Weightbearing CT (WBCT), combined with distance mapping, may improve quantification of PE wear...