Osaka Metropolitan University

Distribution based design framework for ultrasonic process intensification using effective acoustic intensity

Abstract Ultrasonic processes are widely applied for dispersion and structural transformation of layered materials. In such processes, performance is often evaluated based on total input energy. However, because the acoustic pressure field in a liquid medium is inherently spatial...

Developing a Comprehensive Public Health Nursing Practice Model for Promoting Social Inclusion Among Populations Experiencing Social Exclusion: A Qualitative Study

ABSTRACT Aims To develop a comprehensive practice model delineating public health nursing practices that promote social inclusion and illustrate their outcomes in Japan. Design Qualitative descriptive research design. Methods Semi‐structured interviews were conducted with 12 publ...

Anti-inflammatory Effect of Electroconvulsive Therapy and Association Between Brain-Derived Neurotrophic Factor Increases and Nonrelapse

BACKGROUND: Electroconvulsive therapy (ECT) is effective for severe psychiatric disorders, but relapse after a successful acute course of ECT remains common. Identification of biological predictors of relapse is therefore clinically important. In this exploratory prospective stud...

Regional effect of population-based programs promoting salt reduction and potassium intake in Hokkaido: a post hoc analysis of the PoSPIP

Abstract The Population-based Sodium/Potassium Improvement Program is a nonrandomized population-based intervention implemented by the Japanese Society of Hypertension across multiple municipalities and workplaces in Japan. This post hoc regional analysis focused on two municipal...

A Bistable UV-Sensitive Opsin from a Reef Building Coral Showing a Switchable and Tunable Regulation of Gs-Signaling by Different Wavelengths of Light

Abstract Cnidarians possess a large number of opsins in their genomes for their various photoreceptive functions. In particular, they uniquely possess Gs-coupled opsins that induce intracellular cAMP accumulation in a light-dependent manner. These Gs-coupled opsins, cnidopsins, a...

Wannier Based Analysis of the Direct–Indirect Bandgap Transition by Stacking MoS 2 Layers

Molybdenum disulfide (MoS 2 ), a layered van der Waals material, has attracted considerable attention as a promising alternative to graphene for applications in field-effect transistors and nanophotonic devices because of its sizable band gap, high carrier mobility, large on/off...

Healthcare burden and clinical spectrum of symptomatic polycystic liver disease in Japan: a nationwide epidemiological survey

Abstract Background Polycystic liver disease (PLD) is often asymptomatic, but some patients develop symptoms or complications requiring care or intervention. The nationwide burden of symptomatic PLD remains poorly defined. We conducted a nationwide survey to estimate the number a...

Total Synthesis of Antrimycins A and D

Abstract Antrimycins A and D were isolated from Streptomyces bacteria through a screening program for natural products with anti-Mycobacterium tuberculosis activity. These compounds belong to a class of heptapeptide natural products containing four non-proteinogenic amino acids,...

Prion-like transmission of human tau strains in the mouse brain

Abstract Most neurodegenerative diseases are thought to spread through the brain by prion-like mechanisms, in which filamentous protein assemblies self-propagate by templated seeding 1 . Distinct conformations of amyloid filaments may provide the physical basis for the strains th...

Renal function–adjusted initial JAK inhibitor dosing and outcomes in rheumatoid arthritis: from the ANSWER cohort study

INTRODUCTION/OBJECTIVES: To evaluate clinical effectiveness and treatment persistence after renal function-guided reduced-dose initiation of Janus kinase inhibitors (JAKis) in rheumatoid arthritis (RA). METHOD: We analysed 368 adults initiating a JAKi in the ANSWER registry (2013...

Al-substituted Na5FeS4 as earth-abundant positive electrode active materials for all-solid-state sodium batteries

Abstract All-solid-state sodium batteries are attracting attention as next-generation energy devices because of their high safety, low cost, and high energy density. Na 5 FeS 4 , an earth-abundant sodium iron sulfide, is a promising candidate positive electrode active material wi...

Adaptive undulatory locomotion of snake-like robots in dynamic viscous environments via deep reinforcement learning

This paper demonstrates how deep reinforcement learning (DRL) enables adaptive locomotion of snake-like robots in dynamically changing viscous environments. Traditional control methods exhibit inherent performance limitations in such environments. The fundamental challenge of thi...

Functional Heterogeneity of Fusobacterium nucleatum Subspecies in the Immune Microenvironment of Oral Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC) develops through multiple pathogenic and environmental factors. Increasing evidence suggests that the oral microbiota, particularly intratumoral bacteria, is also associated with OSCC progression; however, the relationship between individual ba...

Smartphone step-count patterns and later QMCOO-defined frailty-related risk

Smartphone steps offer low-burden signals. Their incremental value for later frailty-related risk defined by the Questionnaire for Medical Checkup of Old-Old (QMCOO) remains uncertain. We analyzed users of Osaka’s Asmile app. Step-count features from November–December 2024 were r...

Aerobic Zinc-Catalyzed Synthesis of β-Nitroalkenes through the Nitration of Alkenes with Potassium Nitrite

Zinc-catalyzed reaction of terminal aryl alkenes with potassium nitrite selectively affords (E)-β-nitroalkenes under air atmosphere. The transformation is promoted by the reaction of potassium nitrite with acetic anhydride in air and proceeds through a zinc-catalyzed radical proc...

Serum C4/C3 ratio at disease onset predicts end-stage renal disease in microscopic polyangiitis: the multicentre REVEAL cohort

We investigated whether serum complement C3 and C4 levels and the C4/C3 ratio at disease onset were associated with clinical features, renal involvement, and prognosis in microscopic polyangiitis (MPA). Patients were stratified into tertiles according to baseline C3 and C4 levels...

Disrupted development of the retina in the Ccdc85c knockout rat

The coiled-coil domain-containing 85c ( Ccdc85c ) knockout (KO) rat generated by genome editing exhibits hydrocephalus and subcortical heterotopia. In this study, we aimed to further investigate the function of CCDC85C protein in the development of the retina. Expression of CCDC8...

A Bayesian Approach to Nuclear Spin Relaxation Phenomena in Topological Kondo Insulator SmB 6

In studies of the promising topological Kondo insulator (TKI) candidate SmB 6 , nuclear magnetic resonance (NMR) measurements of the spin–lattice relaxation rate, 1/T 1 , have provided crucial insights into this compound: for example, the unique opening of a small hybridization g...

MUSUBOU-AR: An Open-Source Geospatial AR Framework for Integrating Public GIS Data, Field Authoring, and Disaster Walking Tours

Abstract. Conventional hazard maps, public GIS layers, and disaster education materials are essential resources for community disaster risk reduction, but they do not always support in-situ spatial understanding during field-based training. This paper presents MUSUBOUAR, a public...

A Pipeline for Low-Cost Wide-Area 3D Mapping Using LiDAR-Equipped Mobile Devices and Open Data

Abstract. The emergence of LiDAR-equipped mobile devices has enabled low-cost 3D point cloud acquisition. However, accurate 3D model reconstruction using such devices remains confined to individual, locally captured scans. This limitation makes wide-area coverage infeasible witho...