Old Dominion University

Higher education assessments in the age of GenAI: a systematic review

Abstract Assessment in higher education has long centered on core principles such as validity, authenticity, and alignment with learning outcomes, alongside ongoing debates about how best to support academic integrity and meaningful feedback. The emergence of generative artificia...

Plasma Phosphorylated Tau 217 Percentage by Race and Ethnicity in Preclinical Alzheimer Disease

Importance In trials targeting preclinical Alzheimer disease (AD), defined as amyloid pathology without cognitive symptoms, racial and ethnic differences in plasma phosphorylated tau 217 percentage (%p-tau217) may influence screening eligibility. Objective To characterize racial...

Perceptions of artificial Intelligence use in online graduate coursework: a Q methodology study

Artificial Intelligence (AI) is transforming educational practices across all levels, bringing new possibilities and challenges to online graduate programs. With AI tools integrated into coursework, providing automated feedback, personalized resources, and organizational support,...

Understanding Cancer Information Burden and Quality Concerns: The Roles of Medical Statistics Literacy, Online Health Information Confidence, and Social Media

Understanding factors shaping perceptions of cancer-related information is important for public health communication. This study examined associations of three information-related predictors, understanding medical statistics, confidence in online health information, and difficult...

Advertising with HAART: Introducing Human–AI Asymmetric Relationship Theory

Generative artificial intelligence (GenAI)is rapidly reconfiguring advertising from message delivery and optimization to relationship-like exchanges between consumers and brands. While existing work has explained these interactions through social response accounts and interperson...

Failure mechanism of a small vertical pier under post-typhoon wind-wave forcing

This study investigated the failure process and major contributing factors of the north pier at Hongdo, located off the southwestern coast of Korea, which has experienced repeated damage and a history of repair and reinforcement. The 2016 damage event was selected for detailed an...

Ovarian Microvascular Endothelial Cell Migration Is Dysregulated in PMOS

The objective of this study is to investigate whether ovarian microvascular endothelial cells (OMECs) from women with polyendocrine metabolic ovarian syndrome (PMOMECs) exhibit altered angiogenic responses compared with cells from healthy oocyte donors (HOMECs). This is a laborat...

Different Last Millennium El Niño Southern Oscillation Sea Surface Temperature Patterns Drive Disparate North Atlantic Tropical Cyclone Characteristics

Abstract Understanding the relationship between the El Niño‐Southern Oscillation (ENSO) phenomenon and North Atlantic tropical cyclone (TC) activity is critical for both seasonal predictions and future projections of TCs. Unfortunately, the satellite observational era (1970‐pres...

Performance and safety of a multi-cancer early detection test: the PATHFINDER 2 study

Abstract Early cancer detection improves survival; however, most cancer types do not have guideline-recommended screening. We previously reported the first PATHFINDER study that established feasibility of cancer screening with a blood-based multi-cancer early detection (MCED) tes...

Workflow-induced evaluation targets in automation-assisted screening: Implications for cumulative evidence in research synthesis

Abstract Automation-assisted title–abstract screening is routinely evaluated using metrics such as recall, precision, and workload reduction, and results are increasingly summarized across studies. Synthesis presupposes that evaluation results refer to comparable target quantitie...

Co-exposure and interaction effect of a mixture of metals and polycyclic aromatic hydrocarbons on sperm oxidative damage

The study examined interactions between 16 polycyclic aromatic hydrocarbons (PAHs) and six metals in relation to sperm oxidative damage. PAH exposure was assessed using personal breathing-zone measurements, while metal exposure was quantified using urinary concentrations. Semen o...

Missed Opportunities for Stroke Prevention in Patients With Hypertension: A Retrospective Case–Control Study

BACKGROUND: Hypertension is the leading modifiable risk factor for ischemic stroke, yet the adequacy of preventative hypertension care in routine clinical practice remains suboptimal, potentially representing missed opportunities for stroke prevention. We evaluated the associatio...

Carbamate-Functionalized N-Acetyl-D-Glucosamine Derivatives for Gel Formation and Chemiluminescent Properties of their Metallogels

Abstract Sugar-based low-molecular-weight gelators are an interesting and useful class of compounds due to their many applications. Several carbamate derivatives of d-glucose and d-glucosamine have been previously reported as effective gelators, demonstrating that the fine-tuning...

Type 2-low Asthma: Epidemiology, Multiomics, and Emerging Therapies

Abstract Purpose of Review Type 2-low (T2-low) asthma, characterized by low blood and sputum eosinophils and low fractional exhaled nitric oxide (FeNO), remains a major unmet need because of frequent corticosteroid insensitivity and a lack of targeted therapies. This review summa...

The Adaptive Solution of High-Frequency Helmholtz Equations via Multi-Grade Deep Learning

Abstract The Helmholtz equation is fundamental for modeling wave propagation in acoustics, electromagnetics, and geophysics; however, high-frequency regimes remain notoriously difficult due to the severe numerical “pollution effect.” We propose FD-MGDL, an adaptive framework that...

A Scoping Review of the Relationship Between Mini-Map Usage and Spatial Knowledge

Navigational aids are commonplace in today’s technologically advanced world. Tools like GPS devices provide turn-by-turn instructions in place of paper maps, but this potentially comes at the expense of learning the traversed area. This scoping review investigates to what extent...

Autonomous weapons and strategic stability

The increasing number of artificial intelligence (AI) elements within military systems has introduced new forms of security dilemmas related to speed, level of secrecy, and transfer of responsibility from humans to machines. This article addresses the question of whether or how A...

Rhinosinusitis in Adults Receiving Tumor Necrosis Factor Alpha Inhibitors and Anti‐CD20 Therapy: A Scoping Review

ABSTRACT Introduction Immunomodulatory therapies, including tumor necrosis factor alpha (TNF‐α) inhibitors and anti‐CD20 agents, are often used for autoimmune, inflammatory, and neoplastic disorders. While infection risk is well recognized, their association with rhinosinusitis r...

Tail Dependence: The Impact of Risk Spillovers on Real Estate Markets in Times of Economic and Geo‐Political Uncertainty

ABSTRACT The first half of the 2020's has seen a degree of economic and geo‐political uncertainty not observed since the 1970s. This paper looks at how listed real estate is exposed to capital market shocks by estimating Conditional Value‐at‐Risk (CoVaR), which captures the sensi...

The structure of the native cardiac crossbridge in the rigor state

Cardiac contraction is driven by double-headed myosin cycling on cardiac thin filaments, where troponin-tropomyosin regulates myosin access to actin. Prior research used a single-headed myosin bound to bare actin, thereby limiting insight into coordination between myosin heads an...