Norwegian University of Science and Technology

Variation in meningioma recurrence risk estimates across observational cohorts: the influence of calendar time, WHO classifications, geographical settings, and healthcare systems

Abstract Purpose Recurrence risk estimates underpin meningioma research, including molecular classification and clinical trial benchmarking, yet are often based on retrospective or historical data. The aim of this study was to assess the variation of recurrence risk estimates acr...

The Björck classification of the open abdomen revisited: clarifying concepts for modern complex abdomen management

Abstract Introduction The open abdomen (OA) has become an integral component of modern acute care, trauma, and vascular surgery. Since 2009, the Björck classification, amended in 2016, has provided a common language for describing the status and progression of the OA and remains...

From analytic monads to $\infty$-operads through Lawvere theories

We show that a variant of Lurie’s \infty -operads, where the category of finite pointed sets is replaced by that of spans of finite sets, can be identified as precisely the Lawvere theories of the analytic monads previously studied by Gepner, Kock, and the author. This gives an e...

Metal binding site alignment enables network-driven discovery of recurrent geometries across sequence-divergent proteins and drug off-targets

Abstract Metal-binding proteins account for nearly half of the characterized proteome, and they rely on metal-binding sites (MBSs) as critical determinants of their structural stability and biological function. However, methods for comparing their local binding environments lag b...

Naïve adaptive immune receptor repertoires in celiac disease assessed by machine learning; impact of the HLA-DQ2.5 allotype on the TCR repertoire

Abstract The adaptive immune receptor repertoire (AIRR) - the collection of an individual’s B-cell and T-cell receptors (BCRs and TCRs, respectively) - encodes cumulative immune history and is shaped by both germline genetics and environmental exposures. Skewed repertoires have b...

Heterogeneous single-cell dynamics support stable population codes for objects in the mouse anterior cingulate cortex

Remembering object locations is crucial for survival, yet how the anterior cingulate cortex (ACC) encodes spatial features across repeated experiences has not been fully characterized. Using longitudinal calcium imaging in freely moving mice, we tracked excitatory ACC neurons whi...

Brief communication: Towards defining the worst-case breach scenarios and potential flood volumes for moraine-dammed lake outbursts

Abstract. Moraine dam failures are the main source of catastrophic glacial lake outburst floods (GLOFs). The effective GLOF disaster risk management requires reliable identification of areas at risk. While predictive outburst flood modelling benefits from advancing tools and comp...

Fractional angular momentum and quasi-probability densities for angular degrees of freedom

In the present study, we consider quasi-probability densities W[θ, p] and W1/2[θ, p] for pure states depending on two classical parameters θ and p, where −π ≤ θ ≤ π and p can take any real number. For integer values of p, the corresponding marginal distributions W[p] and W1/2[p]...

Enriched experience increases reciprocal synaptic connectivity and coding sparsity in higher-order cortex

The integration of new information during sleep reshapes cortical representations that support categorical knowledge. Auto-associative attractor network theories predict that reciprocal excitatory connections help form stable categorical attractors, but direct evidence is missing...

Tertiary-care management of TB/HIV co-infection in Port Harcourt, Nigeria: A retrospective cohort analysis

ABSTRACT Background Monitoring the treatment of tuberculosis(TB) and human immunodeficiency virus(HIV) co-infection is very important to improve patient management and compliance. This study assessed the treatment outcomes of registered TB/HIV co-infected patients enrolled in the...

A state-of-the-art review on crew competence in maritime and nuclear remote operations

The global maritime shipping sector accounts for approximately 3% of global greenhouse gas (GHG) emissions. In response to climate concerns, the maritime industry is increasingly pursuing technological solutions to reduce emissions. This study is part of the Nuclear Propulsion fo...

Insights into interaction management through backchannels

Abstract This paper analyzes backchannel signals in two signed languages: French Belgian Sign Language (LSFB) and Catalan Sign Language (LSC). While backchannels have been extensively studied in spoken languages, their documentation across signed languages remains sparse in compa...

Learning environment perceptions among occupational therapy students in Norway: sociodemographic, study behaviors, and performance covariates to cluster allocation

Little is known about how learning environment (LE) perceptions cluster within student populations and how such profiles relate to study behaviors and performance. This study aimed to identify clusters of Norwegian occupational therapy students based on their LE perceptions and t...

What Really Drives People-first Public-private Partnerships Adoption? Evidence From Resource-constrained Settings

Abstract This study examines the factors influencing the adoption of People-First Evaluation Methodology (PFEM) in Public-Private Partnerships (PPPs) operating within resource-constrained contexts. Using Partial Least Squares Structural Equation Modeling applied to survey data, t...

Delivering building demand flexibility for grid-interactive operation: from perception and cognition to decision, execution, and verification

As both buildings and power systems undergo rapid decarbonization, demand flexibility (DF) in buildings has emerged as a key enabler for renewable energy integration, grid reliability, energy resilience, and efficient and low carbon operation. By dynamically adjusting building en...

On Goldbach numbers in short intervals

Assuming the Riemann Hypothesis, we prove that for all $$x\geqslant 2$$ , there exists at least one even integer within the interval $$(x, x+123\log ^2x]$$ , that can be expressed as the sum of two primes. This result is an improvement over the recent work of Cully-Hugill and Dud...

Fatigue after ischaemic stroke: A five-year longitudinal study of prevalence and latent trajectory subgroups

Objective To investigate the prevalence and longitudinal course of post-stroke fatigue and identify subgroups with distinct fatigue trajectories up to 5 years post-stroke. Design A prospective, longitudinal, multi-centre cohort study. Setting Hospital stroke units in the Central-...

Distribution of device-measured 24-hour movement behaviours across the cognitive spectrum in older adults: the HUNT study

Abstract Background Key daily physical activities (e.g., standing and walking), postures (sitting and lying), and sleep constitute the 24-h day and have distinct health effects and functional implications. Traditionally studied separately, the distribution of these movement behav...

Genetic clusters of BMI reveal symptom-specific causal effects on depression

Abstract While BMI is phenotypically and genetically associated with depression, the extent to which BMI causes depression and the mechanisms underlying this effect remain unclear. We estimated the causal effect of BMI on depression symptoms, accounting for complexity in both the...

Molecular Structure–TribologicalPerformanceRelationship in Tungsten-Based Polyoxometalate Ionic Liquid LubricantAdditives

Abstract Polyoxometalate ionic liquids (POM-ILs) represent a class of multifunctional materials combining the structural tunability of polyoxometalates (POMs) with the versatile properties of ionic liquids (ILs). In this work, a series of POM-ILs were designed, synthesized, and e...