Northwest University

Discovery of Symmetrical o ‐Methylpyridine Substituted Tertiary Amines and Dy(III) Complexes as Metallo‐β‐Lactamase Inhibitor and Antimicrobial

Due to the lack of metallo‐β‐lactamase (MβL) inhibitors for clinical purposes, the antibiotic resistance mediated by MβL poses a clear threat to public health. In this work, twelve symmetrical o ‐methylpyridine substituted tertiary amines P1 – P6 and their Dy(III) complexes D1 –...

Targeting chondroitin synthase 1 attenuates hyperplastic arterial remodeling via gene therapy

Chondroitin sulfate glycosaminoglycans accumulate excessively in the extracellular matrix during pathological remodeling and exacerbate cardiovascular deterioration. Here we show that chondroitin synthase 1 (CHSY1) is the primary enzyme responsible for chondroitin sulfate synthes...

AI knowledge capability and innovation: the power of cognitive processing and empowerment

Purpose This study aims to integrate ideas from organizational learning theory with new AI capabilities to investigate how AI-driven knowledge processes may improve innovation performance. Specifically, this study explores the process in which AI-based (AI Ba) knowledge productio...

An illustrated key to the species of Gasteruption Latreille (Hymenoptera, Gasteruptiidae) from Palaearctic China, with description of four new species

(Tournier, 1877),

Overpressure Prediction of Reservoirs Based on Multiple Regression of Geological Factors—A Case Study of Bohai Bay, Bozhong Depression, China

Accurate prediction of overpressure in deep reservoirs is critical for hydrocarbon ex-ploration and development. Conventional approaches, such as interpolation of sin-gle-well pressure data and seismic inversion, often produce considerable errors and uncertainty when predicting o...

Predicting Engineering-Defined Failure Risk Levels of Metal-Loss-Related Pipeline Girth Weld Defects Under Incomplete Engineering Data

Predicting engineering-defined failure risk levels for pipeline girth welds …is challenging because engineering records may be incomplete Conventional models often struggle with incomplete engineering inputs, as standard imputation pipelines tend to treat estimated values as equa...

Polyzwitterion grafted onto PET microfiltration membrane via surface-initiated ATRP for enhanced antifouling performance

To address the challenges of membrane fouling, we present a surface modification strategy that combines the high efficiency of surface-initiated atom transfer radical polymerization (SI-ATRP) with the excellent antifouling properties of zwitterionic polymers. A poly(St- co -VBC)...

Multi-Analytical Characterization of the Earthen Plaster and Ground Layer from the Nirvana Platform in Cave No. 47 of the Kizil Grottoes, Xinjiang, China

The Nirvana platform in Cave No. 47 of the Kizil Grottoes preserves an important example of early Buddhist earthen plaster and ground layer manufacture along the Silk Roads. This study investigated the material composition and stratigraphic sequence of its earthen plaster and gro...

Nonlinear and lagged associations between active-layer thickness and vegetation greenness in the source reach of the Yangtze River basin from 1990 to 2024

Permafrost degradation can alter alpine vegetation through changing hydrothermal conditions, but nonlinear relationships between active-layer thickness (ALT) and vegetation and their temporal lags remain poorly quantified on the Qinghai–Tibet Plateau. We integrated a cross-sensor...

A Shallow‐Marine Ecosystem Before Initial Tibetan Plateau Uplift

Abstract The uplift of the Tibetan Plateau profoundly influences global atmospheric circulation, sediment transport, and biodiversity, but its pre‐uplift marine paleoenvironment remains poorly understood. Here we report the first discovery of an in situ benthic fossil assemblage...

Afforestation enhances ecosystem stability in the farming-pastoral ecotone of northern China, but its effects are constrained by water availability

Abstract The farming-pastoral ecotone of northern China (FPENC), a typical semi-agricultural and semi-pastoral ecologically fragile zone, has long faced controversy over afforestation due to its water-limited environment, raising concerns about how afforestation affects this frag...

Topological Reinforcement of Rhizosphere Microbial Networks Facilitates the Invasive Superiority of Spartina anglica

Rhizosphere microbial interaction patterns underpin the resilience and dominance of invasive plants in fluctuating coastal salt marshes. We compared the rhizosphere microbial communities of the invasive Spartina anglica and the native Spartina maritima across varying distances fr...

Flexible Room‐Temperature Phosphorescent Materials With Matrix‐Independent Luminescence Enabled by Host–Guest Encapsulation

ABSTRACT Flexible room‐temperature phosphorescence (RTP) materials hold great promise for a wide range of optical applications. However, the strong interdependence between luminescent and mechanical properties severely hampers further advances in this field. Herein, we report a γ...

Morpho-functional innovations in Shibantan fossils fuel Ediacaran frond debates

The Ediacara biota represents Earth’s earliest complex macroscopic organisms, but their biology and ecology remain poorly understood. Here we report Dengyingia pennata gen. et sp. nov., an exceptionally preserved frondose fossil from the late Ediacaran ( ~550–543 Ma) Shibantan li...

Multi-analytical investigation on materials and techniques of wall paintings in Kizil Giant Buddha Cave

This study investigates the wall paintings in Cave No. 47 of the Kizil Grottoes, the earliest surviving Giant Buddha cave. p-XRF, SEM-EDX, XRD, and micro-Raman spectroscopy were used to characterize the painting materials, stratigraphy, and alteration products. Three plaster and...

Research on a Differential Game Considering Endurance and Marketing Effort for eVTOL Under a Subsidy Policy

Electric vertical takeoff and landing (eVTOL) represents a novel mode of transportation emerging within the low-altitude economy framework, exhibiting extensive development prospects. As a widely adopted incentive policy, government subsidy constitutes a crucial method for suppor...

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

Pathological cartilage calcification represents a pivotal pathological alteration in osteoarthritis (OA), yet its underlying mechanisms remain poorly understood. Exosomes are involved in facilitating calcification, and their biogenesis may be linked to autophagy disruption. Howev...

Genomic predisposition is associated with the direction of sex chromosome evolution

Sex chromosome evolution is among the most dynamic genomic innovations in vertebrates, yet why some lineages evolve XY while others evolve ZW remains unclear. Using chromosome-level genomes from 19 geckos, we found that gecko sex chromosomes originated independently from 16 ances...

Complete genome-derived metabolic interactions reveal the impact of gut ecology on human health

Abstract Metabolic interactions govern gut microbiome assembly, yet functional rules remain obscured by genomic incompleteness and fragmentation. Here, we leverage 1,150 complete genomes to construct genome-scale metabolic models, demonstrating that draft genomes introduce system...

Evaluation of modal density for fluid-loaded composite cylindrical shells

Abstract A modified modal-density evaluation method is proposed for fluid-loaded composite cylindrical shells within the Statistical Energy Analysis (SEA) framework. The surrounding-fluid effect is represented by an in-band added surface density (ASD), which is obtained by averag...