North Sichuan Medical University

Evaluation of the safety and efficacy of 225Ac-PSMA-CY313 in metastatic castration-resistant prostate cancer: preliminary results

Abstract Objective Metastatic castration-resistant prostate cancer (mCRPC) remains associated with poor long-term outcomes, and survival under current treatment is modest. Prostate-specific membrane antigen (PSMA)-targeted alpha therapy using 225 Ac exhibits superior cytotoxicity...

MRI-based radiomic models of subchondral bone for predicting the occurrence of knee osteoarthritis

To extract the MRI-based radiomic features of subchondral bone, and establish multi-regional radiomic models and delta-radiomic models for predicting the 2-year risk of knee osteoarthritis (KOA). The data used in this study were obtained from the osteoarthritis initiative (OAI)....

The effect of informational content redundancy in short instructional videos on the ESD teaching effectiveness

With the advancement of digital education, short videos have emerged as a powerful teaching and learning, demonstrating unprecedented potential for education for sustainable development (ESD). This study examines how learners’ perceived information content redundancy in ESD-relat...

Preoperative enhanced CT lymph node parameters and postoperative pathology for predicting regional control failure after neck dissection for oral cancer

Background Regional control failure (RCF) after neck dissection (ND) remains a major determinant of poor survival in oral squamous cell carcinoma (OSCC). The objective of this research was to devise and confirm a combined predictive model incorporating preoperative contrast-enhan...

A machine learning model based on mPASS and imaging features for early assessment of clinically relevant outcomes in acute pancreatitis

To develop and validate a machine learning (ML) model based on the modified pancreatitis activity scoring system (mPASS) and imaging features for the early assessment of multiple clinically relevant outcomes in acute pancreatitis (AP). A retrospective cohort of 420 AP patients wa...