North Carolina School of Science and Mathematics

Well-posedness and singularity formation beyond the Yudovich class

We introduce a local-in-time existence and uniqueness class for solutions to the 2d Euler equation with unbounded vorticity. Furthermore, we show that solutions belonging to this class can develop stronger singularities in finite time, meaning that they experience finite time blo...

Development of a STEAP1-targeted prostate cancer specific antibody drug conjugate platform with immunostimulatory properties

Background: Patients with prostate cancer who develop androgen pathway modulation resistant (APMR) disease face lethal outcomes despite advances in androgen receptor-pathway inhibitors, chemotherapy, and PSMA-directed radioligands. Antibody-drug conjugates (ADCs) have demonstrate...